Immune checkpoint inhibitors: recent progress and potential biomarkers P Darvin, SM Toor, VS Nair, E Elkord Experimental & molecular medicine 50 (12), 1-11, 2018 | 1866 | 2018 |
Immune checkpoint inhibitors in cancer therapy: a focus on T‐regulatory cells V Sasidharan Nair, E Elkord Immunology and cell biology 96 (1), 21-33, 2018 | 289 | 2018 |
T‐cell responses and therapies against SARS‐CoV‐2 infection SM Toor, R Saleh, V Sasidharan Nair, RZ Taha, E Elkord Immunology 162 (1), 30-43, 2021 | 202 | 2021 |
Immune Checkpoints in the Tumor Microenvironment SM Toor, VS Nair, J Decock, E Elkord Semin Cancer Biology, 2019 | 180 | 2019 |
Vitamin C facilitates demethylation of the Foxp3 enhancer in a Tet-dependent manner V Sasidharan Nair, MH Song, KI Oh The journal of immunology 196 (5), 2119-2131, 2016 | 173 | 2016 |
DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer V Sasidharan Nair, H El Salhat, RZ Taha, A John, BR Ali, E Elkord Clinical epigenetics 10, 1-12, 2018 | 124 | 2018 |
Dual inhibition of STAT1 and STAT3 activation downregulates expression of PD-L1 in human breast cancer cells V Sasidharan Nair, SM Toor, BR Ali, E Elkord Expert opinion on therapeutic targets 22 (6), 547-557, 2018 | 103 | 2018 |
Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer R Saleh, RZ Taha, SM Toor, V Sasidharan Nair, K Murshed, M Khawar, ... Cancer Immunology, Immunotherapy 69, 1989-1999, 2020 | 91 | 2020 |
DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer V Sasidharan Nair, SM Toor, RZ Taha, H Shaath, E Elkord Clinical epigenetics 10, 1-9, 2018 | 85 | 2018 |
Role of epigenetic modifications in inhibitory immune checkpoints in cancer development and progression R Saleh, SM Toor, V Sasidharan Nair, E Elkord Frontiers in immunology 11, 544793, 2020 | 67 | 2020 |
PD-L1 blockade by atezolizumab downregulates signaling pathways associated with tumor growth, metastasis, and hypoxia in human triple negative breast cancer R Saleh, RZ Taha, V Sasidharan Nair, NM Alajez, E Elkord Cancers 11 (8), 1050, 2019 | 67 | 2019 |
DNA demethylation of the Foxp3 enhancer is maintained through modulation of ten-eleven-translocation and DNA methyltransferases VS Nair, MH Song, M Ko, KI Oh Molecules and cells 39 (12), 888-897, 2016 | 67 | 2016 |
DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients AA Elashi, V Sasidharan Nair, RZ Taha, H Shaath, E Elkord Oncoimmunology 8 (2), e1542918, 2019 | 57 | 2019 |
PD-L1 expression in human breast cancer stem cells is epigenetically regulated through posttranslational histone modifications P Darvin, V Sasidharan Nair, E Elkord Journal of oncology 2019, 2019 | 56 | 2019 |
Vitamin C enhances the expression of IL17 in a Jmjd2–dependent manner MH Song, VS Nair, KI Oh BMB reports 50 (1), 49, 2017 | 54 | 2017 |
Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer V Sasidharan Nair, R Saleh, SM Toor, RZ Taha, AA Ahmed, MA Kurer, ... Clinical epigenetics 12, 1-15, 2020 | 52 | 2020 |
Down-regulation of Tet2 prevents TSDR demethylation in IL2 deficient regulatory T cells VS Nair, KI Oh Biochemical and biophysical research communications 450 (1), 918-924, 2014 | 52 | 2014 |
Integrated transcriptome and pathway analyses revealed multiple activated pathways in breast cancer R Vishnubalaji, V Sasidharan Nair, K Ouararhni, E Elkord, NM Alajez Frontiers in oncology 9, 910, 2019 | 38 | 2019 |
Transcriptomic analyses revealed systemic alterations in gene expression in circulation and tumor microenvironment of colorectal cancer patients H Shaath, S Toor, VS Nair, E Elkord, NM Alajez Cancers 11 (12), 1994, 2019 | 33 | 2019 |
Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment V Sasidharan Nair, R Saleh, SM Toor, FS Cyprian, E Elkord Cancer immunology, immunotherapy 70, 2103-2121, 2021 | 27 | 2021 |