The mechanisms of alloxan-and streptozotocin-induced diabetes S Lenzen Diabetologia 51 (2), 216-226, 2008 | 3450 | 2008 |
Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities M Cnop, N Welsh, JC Jonas, A Jorns, S Lenzen, DL Eizirik Diabetes 54 (suppl_2), S97-S107, 2005 | 1950 | 2005 |
Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells M Tiedge, S Lortz, J Drinkgern, S Lenzen Diabetes 46 (11), 1733-1742, 1997 | 1517 | 1997 |
Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues S Lenzen, J Drinkgern, M Tiedge Free Radical Biology and Medicine 20 (3), 463-466, 1996 | 1395 | 1996 |
Oxidative stress: the vulnerable β-cell S Lenzen Biochemical Society Transactions 36 (3), 343-347, 2008 | 642 | 2008 |
Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin M Elsner, B Guldbakke, M Tiedge, R Munday, S Lenzen Diabetologia 43, 1528-1533, 2000 | 588 | 2000 |
Alloxan: history and mechanism of action S Lenzen, U Panten Diabetologia 31, 337-342, 1988 | 427 | 1988 |
Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells BJ Zünkler, S Lenzen, K Manner, U Panten, G Trube Naunyn-Schmiedeberg's archives of pharmacology 337, 225-230, 1988 | 271 | 1988 |
Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species. M Tiedge, S Lortz, R Munday, S Lenzen Diabetes 47 (10), 1578-1585, 1998 | 262 | 1998 |
Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes. S Lortz, M Tiedge, T Nachtwey, AE Karlsen, J Nerup, S Lenzen Diabetes 49 (7), 1123-1130, 2000 | 245 | 2000 |
Peroxisome-generated hydrogen peroxide as important mediator of lipotoxicity in insulin-producing cells M Elsner, W Gehrmann, S Lenzen Diabetes 60 (1), 200-208, 2011 | 237 | 2011 |
A fresh view of glycolysis and glucokinase regulation: history and current status S Lenzen Journal of Biological Chemistry 289 (18), 12189-12194, 2014 | 210 | 2014 |
Control of insulin secretion by sulfonylureas, meglitinide and diazoxide in relation to their binding to the sulfonylurea receptor in pancreatic islets U Panten, J Burgfeld, F Goerke, M Rennicke, M Schwanstecher, ... Biochemical pharmacology 38 (8), 1217-1229, 1989 | 210 | 1989 |
Role of metabolically generated reactive oxygen species for lipotoxicity in pancreatic β‐cells W Gehrmann, M Elsner, S Lenzen Diabetes, Obesity and Metabolism 12, 149-158, 2010 | 209 | 2010 |
Thiol-group reactivity, hydrophilicity and stability of alloxan, its reduction products and its N-methyl derivatives and a comparison with ninhydrin S Lenzen, R Munday Biochemical pharmacology 42 (7), 1385-1391, 1991 | 202 | 1991 |
Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-κB activation in insulin-producing cells AK Azevedo-Martins, S Lortz, S Lenzen, R Curi, DL Eizirik, M Tiedge Diabetes 52 (1), 93-101, 2003 | 201 | 2003 |
Thyroid hormones, gonadal and adrenocortical steroids and the function of the islets of Langerhans S Lenzen, CJ Bailey Endocrine Reviews 5 (3), 411-434, 1984 | 198 | 1984 |
Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan M Elsner, M Tiedge, B Guldbakke, R Munday, S Lenzen Diabetologia 45, 1542-1549, 2002 | 185 | 2002 |
Comparative toxicity of alloxan, N-alkylalloxans and ninhydrin to isolated pancreatic islets in vitro A Jorns, R Munday, M Tiedge, S Lenzen Journal of endocrinology 155 (2), 283-294, 1997 | 168 | 1997 |
Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines E Gurgul, S Lortz, M Tiedge, A Jorns, S Lenzen Diabetes 53 (9), 2271-2280, 2004 | 167 | 2004 |