The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen S Crotty, D Maag, JJ Arnold, W Zhong, JYN Lau, Z Hong, R Andino, ... Nature medicine 6 (12), 1375-1379, 2000 | 1065 | 2000 |
Addition of the PARP inhibitor veliparib plus carboplatin or carboplatin alone to standard neoadjuvant chemotherapy in triple-negative breast cancer (BrighTNess): a randomised … S Loibl, J O'Shaughnessy, M Untch, WM Sikov, HS Rugo, MD McKee, ... The lancet oncology 19 (4), 497-509, 2018 | 682 | 2018 |
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome LA Passmore, TM Schmeing, D Maag, DJ Applefield, MG Acker, MA Algire, ... Molecular cell 26 (1), 41-50, 2007 | 424 | 2007 |
Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin D Maag, C Castro, Z Hong, CE Cameron Journal of biological chemistry 276 (49), 46094-46098, 2001 | 394 | 2001 |
Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain A Chakraborty, MA Koldobskiy, NT Bello, M Maxwell, JJ Potter, KR Juluri, ... Cell 143 (6), 897-910, 2010 | 384 | 2010 |
Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation MA Algire, D Maag, JR Lorsch Molecular cell 20 (2), 251-262, 2005 | 336 | 2005 |
Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer (BROCADE3): a randomised, double-blind, placebo-controlled, phase 3 trial V Diéras, HS Han, B Kaufman, H Wildiers, M Friedlander, JP Ayoub, ... The lancet oncology 21 (10), 1269-1282, 2020 | 267 | 2020 |
A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon D Maag, CA Fekete, Z Gryczynski, JR Lorsch Molecular cell 17 (2), 265-275, 2005 | 256 | 2005 |
Mechanistic Dissection of PARP1 Trapping and the Impact on In Vivo Tolerability and Efficacy of PARP Inhibitors TA Hopkins, Y Shi, LE Rodriguez, LR Solomon, CK Donawho, ... Molecular Cancer Research 13 (11), 1465-1477, 2015 | 236 | 2015 |
Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1 AY Kim, Z Tang, Q Liu, KN Patel, D Maag, Y Geng, X Dong Cell 133 (3), 475-485, 2008 | 220 | 2008 |
Iniparib Nonselectively Modifies Cysteine-Containing Proteins in Tumor Cells and Is Not a Bona Fide PARP Inhibitor X Liu, Y Shi, DX Maag, JP Palma, MJ Patterson, PA Ellis, BW Surber, ... Clinical Cancer Research 18 (2), 510-523, 2012 | 218 | 2012 |
Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo YN Cheung, D Maag, SF Mitchell, CA Fekete, MA Algire, JE Takacs, ... Genes & development 21 (10), 1217-1230, 2007 | 207 | 2007 |
The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex Y He, S Selvaraju, ML Curtin, CG Jakob, H Zhu, KM Comess, B Shaw, ... Nature chemical biology 13 (4), 389-395, 2017 | 205 | 2017 |
PARP1 trapping by PARP inhibitors drives cytotoxicity in both cancer cells and healthy bone marrow TA Hopkins, WB Ainsworth, PA Ellis, CK Donawho, EL DiGiammarino, ... Molecular Cancer Research 17 (2), 409-419, 2019 | 199 | 2019 |
Discovery and development of potent and selective inhibitors of histone methyltransferase g9a RF Sweis, M Pliushchev, PJ Brown, J Guo, F Li, D Maag, AM Petros, ... ACS medicinal chemistry letters 5 (2), 205-209, 2014 | 186 | 2014 |
Development and characterization of a reconstituted yeast translation initiation system MA Algire, D Maag, P Savio, MG Acker, SZ Tarun, AB Sachs, K Asano, ... Rna 8 (3), 382-397, 2002 | 184 | 2002 |
Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity BS Shin, D Maag, A Roll-Mecak, MS Arefin, SK Burley, JR Lorsch, ... Cell 111 (7), 1015-1025, 2002 | 171 | 2002 |
Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase S Kim, SF Kim, D Maag, MJ Maxwell, AC Resnick, KR Juluri, ... Cell metabolism 13 (2), 215-221, 2011 | 159 | 2011 |
Template/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase W Zhong, E Ferrari, CA Lesburg, D Maag, SKB Ghosh, CE Cameron, ... Journal of virology 74 (19), 9134-9143, 2000 | 151 | 2000 |
N‐and C‐terminal residues of eIF1A have opposing effects on the fidelity of start codon selection CA Fekete, SF Mitchell, VA Cherkasova, D Applefield, MA Algire, D Maag, ... The EMBO journal 26 (6), 1602-1614, 2007 | 148 | 2007 |