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David Maag
David Maag
Scientific Director, AbbVie
Verified email at abbvie.com
Title
Cited by
Cited by
Year
The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen
S Crotty, D Maag, JJ Arnold, W Zhong, JYN Lau, Z Hong, R Andino, ...
Nature medicine 6 (12), 1375-1379, 2000
10652000
Addition of the PARP inhibitor veliparib plus carboplatin or carboplatin alone to standard neoadjuvant chemotherapy in triple-negative breast cancer (BrighTNess): a randomised …
S Loibl, J O'Shaughnessy, M Untch, WM Sikov, HS Rugo, MD McKee, ...
The lancet oncology 19 (4), 497-509, 2018
6822018
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome
LA Passmore, TM Schmeing, D Maag, DJ Applefield, MG Acker, MA Algire, ...
Molecular cell 26 (1), 41-50, 2007
4242007
Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin
D Maag, C Castro, Z Hong, CE Cameron
Journal of biological chemistry 276 (49), 46094-46098, 2001
3942001
Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain
A Chakraborty, MA Koldobskiy, NT Bello, M Maxwell, JJ Potter, KR Juluri, ...
Cell 143 (6), 897-910, 2010
3842010
Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation
MA Algire, D Maag, JR Lorsch
Molecular cell 20 (2), 251-262, 2005
3362005
Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer (BROCADE3): a randomised, double-blind, placebo-controlled, phase 3 trial
V Diéras, HS Han, B Kaufman, H Wildiers, M Friedlander, JP Ayoub, ...
The lancet oncology 21 (10), 1269-1282, 2020
2672020
A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon
D Maag, CA Fekete, Z Gryczynski, JR Lorsch
Molecular cell 17 (2), 265-275, 2005
2562005
Mechanistic Dissection of PARP1 Trapping and the Impact on In Vivo Tolerability and Efficacy of PARP Inhibitors
TA Hopkins, Y Shi, LE Rodriguez, LR Solomon, CK Donawho, ...
Molecular Cancer Research 13 (11), 1465-1477, 2015
2362015
Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1
AY Kim, Z Tang, Q Liu, KN Patel, D Maag, Y Geng, X Dong
Cell 133 (3), 475-485, 2008
2202008
Iniparib Nonselectively Modifies Cysteine-Containing Proteins in Tumor Cells and Is Not a Bona Fide PARP Inhibitor
X Liu, Y Shi, DX Maag, JP Palma, MJ Patterson, PA Ellis, BW Surber, ...
Clinical Cancer Research 18 (2), 510-523, 2012
2182012
Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo
YN Cheung, D Maag, SF Mitchell, CA Fekete, MA Algire, JE Takacs, ...
Genes & development 21 (10), 1217-1230, 2007
2072007
The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex
Y He, S Selvaraju, ML Curtin, CG Jakob, H Zhu, KM Comess, B Shaw, ...
Nature chemical biology 13 (4), 389-395, 2017
2052017
PARP1 trapping by PARP inhibitors drives cytotoxicity in both cancer cells and healthy bone marrow
TA Hopkins, WB Ainsworth, PA Ellis, CK Donawho, EL DiGiammarino, ...
Molecular Cancer Research 17 (2), 409-419, 2019
1992019
Discovery and development of potent and selective inhibitors of histone methyltransferase g9a
RF Sweis, M Pliushchev, PJ Brown, J Guo, F Li, D Maag, AM Petros, ...
ACS medicinal chemistry letters 5 (2), 205-209, 2014
1862014
Development and characterization of a reconstituted yeast translation initiation system
MA Algire, D Maag, P Savio, MG Acker, SZ Tarun, AB Sachs, K Asano, ...
Rna 8 (3), 382-397, 2002
1842002
Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity
BS Shin, D Maag, A Roll-Mecak, MS Arefin, SK Burley, JR Lorsch, ...
Cell 111 (7), 1015-1025, 2002
1712002
Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase
S Kim, SF Kim, D Maag, MJ Maxwell, AC Resnick, KR Juluri, ...
Cell metabolism 13 (2), 215-221, 2011
1592011
Template/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase
W Zhong, E Ferrari, CA Lesburg, D Maag, SKB Ghosh, CE Cameron, ...
Journal of virology 74 (19), 9134-9143, 2000
1512000
N‐and C‐terminal residues of eIF1A have opposing effects on the fidelity of start codon selection
CA Fekete, SF Mitchell, VA Cherkasova, D Applefield, MA Algire, D Maag, ...
The EMBO journal 26 (6), 1602-1614, 2007
1482007
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