Recruitment of DNA methyltransferase I to DNA repair sites O Mortusewicz, L Schermelleh, J Walter, MC Cardoso, H Leonhardt Proceedings of the National Academy of Sciences 102 (25), 8905-8909, 2005 | 425 | 2005 |
Feedback-regulated poly (ADP-ribosyl) ation by PARP-1 is required for rapid response to DNA damage in living cells O Mortusewicz, JC Ame, V Schreiber, H Leonhardt Nucleic acids research 35 (22), 7665-7675, 2007 | 362 | 2007 |
Poly (ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression C Boehler, LR Gauthier, O Mortusewicz, DS Biard, JM Saliou, A Bresson, ... Proceedings of the National Academy of Sciences 108 (7), 2783-2788, 2011 | 321 | 2011 |
Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress RM Jones, O Mortusewicz, I Afzal, M Lorvellec, P Garcia, T Helleday, ... Oncogene 32 (32), 3744, 2013 | 308 | 2013 |
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation T Visnes, A Cázares-Körner, W Hao, O Wallner, G Masuyer, O Loseva, ... Science 362 (6416), 834-839, 2018 | 194 | 2018 |
Cancer-specific synthetic lethality between ATR and CHK1 kinase activities K Sanjiv, A Hagenkort, JM Calderón-Montaño, T Koolmeister, PM Reaper, ... Cell reports 14 (2), 298-309, 2016 | 150 | 2016 |
PARG is recruited to DNA damage sites through poly (ADP-ribose)-and PCNA-dependent mechanisms O Mortusewicz, E Fouquerel, JC Ame, H Leonhardt, V Schreiber Nucleic acids research 39 (12), 5045-5056, 2011 | 145 | 2011 |
Differential recruitment of DNA Ligase I and III to DNA repair sites O Mortusewicz, U Rothbauer, MC Cardoso, H Leonhardt Nucleic acids research 34 (12), 3523-3532, 2006 | 129 | 2006 |
Timeless interacts with PARP-1 to promote homologous recombination repair S Xie, O Mortusewicz, HT Ma, P Herr, RYC Poon, T Helleday, C Qian Molecular cell 60 (1), 163-176, 2015 | 120 | 2015 |
A fluorescent two-hybrid assay for direct visualization of protein interactions in living cells K Zolghadr, O Mortusewicz, U Rothbauer, R Kleinhans, H Goehler, ... Molecular & Cellular Proteomics 7 (11), 2279-2287, 2008 | 107 | 2008 |
XRCC1 and PCNA are loading platforms with distinct kinetic properties and different capacities to respond to multiple DNA lesions O Mortusewicz, H Leonhardt BMC molecular biology 8 (1), 81, 2007 | 93 | 2007 |
DNA-PKcs and PARP1 bind to unresected stalled DNA replication forks where they recruit XRCC1 to mediate repair S Ying, Z Chen, AL Medhurst, JA Neal, Z Bao, O Mortusewicz, ... Cancer research 76 (5), 1078-1088, 2016 | 89 | 2016 |
Role for hACF1 in the G2/M damage checkpoint S Sanchez-Molina, O Mortusewicz, B Bieber, S Auer, M Eckey, ... Nucleic acids research 39 (19), 8445-8456, 2011 | 76 | 2011 |
Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen P Perucca, O Cazzalini, O Mortusewicz, D Necchi, M Savio, T Nardo, ... J Cell Sci 119 (8), 1517-1527, 2006 | 72 | 2006 |
Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites O Mortusewicz, W Roth, N Li, MC Cardoso, M Meisterernst, H Leonhardt The Journal of cell biology 183 (5), 769-776, 2008 | 65 | 2008 |
The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing M Tanikawa, K Sanjiv, T Helleday, P Herr, O Mortusewicz Oncogenesis 5 (12), e280, 2016 | 53 | 2016 |
PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites O Mortusewicz, B Evers, T Helleday Oncogene 35 (6), 761, 2016 | 49 | 2016 |
Early replication fragile sites: where replication–transcription collisions cause genetic instability O Mortusewicz, P Herr, T Helleday The EMBO journal 32 (4), 493-495, 2013 | 47 | 2013 |
CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair CE Ström, O Mortusewicz, D Finch, JL Parsons, A Lagerqvist, ... DNA repair 10 (9), 961-969, 2011 | 47 | 2011 |
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress T Visnes, C Benítez-Buelga, A Cázares-Körner, K Sanjiv, BMF Hanna, ... Nucleic acids research 48 (21), 12234-12251, 2020 | 43 | 2020 |