Exploiting lymphatic transport and complement activation in nanoparticle vaccines ST Reddy, AJ Van Der Vlies, E Simeoni, V Angeli, GJ Randolph, ... Nature biotechnology 25 (10), 1159-1164, 2007 | 1328 | 2007 |
Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance RA Maldonado, RA LaMothe, JD Ferrari, AH Zhang, RJ Rossi, PN Kolte, ... Proceedings of the National Academy of Sciences 112 (2), E156-E165, 2015 | 392 | 2015 |
Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage DA Rothenfluh, H Bermudez, CP O’Neil, JA Hubbell Nature materials 7 (3), 248-254, 2008 | 330 | 2008 |
Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine … PO Ilyinskii, CJ Roy, CP O’Neil, EA Browning, LA Pittet, DH Altreuter, ... Vaccine 32 (24), 2882-2895, 2014 | 173 | 2014 |
Improving the efficacy and safety of biologic drugs with tolerogenic nanoparticles TK Kishimoto, JD Ferrari, RA LaMothe, PN Kolte, AP Griset, C O'Neil, ... Nature nanotechnology 11 (10), 890-899, 2016 | 164 | 2016 |
Synthesis of pyridyl disulfide-functionalized nanoparticles for conjugating thiol-containing small molecules, peptides, and proteins AJ Van Der Vlies, CP O’Neil, U Hasegawa, N Hammond, JA Hubbell Bioconjugate chemistry 21 (4), 653-662, 2010 | 136 | 2010 |
Engineering complement activation on polypropylene sulfide vaccine nanoparticles SN Thomas, AJ van der Vlies, CP O’Neil, ST Reddy, SY Shann, ... Biomaterials 32 (8), 2194-2203, 2011 | 128 | 2011 |
A novel method for the encapsulation of biomolecules into polymersomes via direct hydration CP O’Neil, T Suzuki, D Demurtas, A Finka, JA Hubbell Langmuir 25 (16), 9025-9029, 2009 | 122 | 2009 |
Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival KY Dane, C Nembrini, AA Tomei, JK Eby, CP O'Neil, D Velluto, MA Swartz, ... Journal of controlled release 156 (2), 154-160, 2011 | 108 | 2011 |
Precision intracellular delivery based on optofluidic polymersome rupture AE Vasdekis, EA Scott, CP O’Neil, D Psaltis, JA Hubbell ACS nano 6 (9), 7850-7857, 2012 | 103 | 2012 |
Nanoparticles for immunotherapy JA Hubbell, CP O'neil, ST Reddy, MA Swartz, D Velluto, A van Der Vlies, ... US Patent 8,323,696, 2012 | 88 | 2012 |
Aggregation Behavior of Poly(ethylene glycol-bl-propylene sulfide) Di- and Triblock Copolymers in Aqueous Solution S Cerritelli, CP O’Neil, D Velluto, A Fontana, M Adrian, J Dubochet, ... Langmuir 25 (19), 11328-11335, 2009 | 87 | 2009 |
TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25 EA Thompson, S Ols, K Miura, K Rausch, DL Narum, M Spångberg, ... JCI insight 3 (10), 2018 | 64 | 2018 |
Extracellular matrix binding mixed micelles for drug delivery applications CP O'Neil, AJ van der Vlies, D Velluto, C Wandrey, D Demurtas, ... Journal of controlled release 137 (2), 146-151, 2009 | 64 | 2009 |
A benzene-core trinuclear Gd III complex: towards the optimization of relaxivity for MRI contrast agent applications at high magnetic field JB Livramento, L Helm, A Sour, C O'Neil, AE Merbach, É Tóth Dalton Transactions, 1195-1202, 2008 | 56 | 2008 |
Methods for administering synthetic nanocarriers that generate humoral and cytotoxic T lymphocyte responses DH Altreuter, C O'neil, P Ilyinskii US Patent 10,933,129, 2021 | 50 | 2021 |
Superparamagnetic nanoparticles as a powerful systems biology characterization tool in the physiological context J Salaklang, B Steitz, A Finka, CP O'Neil, M Moniatte, AJ Van Der Vlies, ... Angewandte Chemie International Edition 47 (41), 7857-7860, 2008 | 45 | 2008 |
Polymer micelles with pyridyl disulfide-coupled antigen travel through lymphatics and show enhanced cellular responses following immunization JK Eby, KY Dane, CP O’Neil, S Hirosue, MA Swartz, JA Hubbell Acta biomaterialia 8 (9), 3210-3217, 2012 | 40 | 2012 |
Enzymatic-and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs) SS Yu, RL Scherer, RA Ortega, CS Bell, CP O'Neil, JA Hubbell, ... Journal of nanobiotechnology 9, 1-10, 2011 | 37 | 2011 |
Assessing the Role of Poly(ethylene glycol-bl-propylene sulfide) (PEG-PPS) Block Copolymers in the Preparation of Carbon Nanotube Biocompatible Dispersions EM Di Meo, A Di Crescenzo, D Velluto, CP O’Neil, D Demurtas, ... Macromolecules 43 (7), 3429-3437, 2010 | 36 | 2010 |