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Fan Wu
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Computer modeling of mitochondrial tricarboxylic acid cycle, oxidative phosphorylation, metabolite transport, and electrophysiology
F Wu, F Yang, KC Vinnakota, DA Beard
Journal of Biological Chemistry 282 (34), 24525-24537, 2007
2232007
Phosphate metabolite concentrations and ATP hydrolysis potential in normal and ischaemic hearts
F Wu, EY Zhang, J Zhang, RJ Bache, DA Beard
The Journal of physiology 586 (17), 4193-4208, 2008
1232008
Oxidative ATP synthesis in skeletal muscle is controlled by substrate feedback
F Wu, JAL Jeneson, DA Beard
American Journal of Physiology-Cell Physiology 292 (1), C115-C124, 2007
1042007
Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism
F Wu, J Zhang, DA Beard
Proceedings of the National Academy of Sciences 106 (17), 7143-7148, 2009
782009
Preclinical QSP modeling in the pharmaceutical industry: an IQ consortium survey examining the current landscape
MJMA Nijsen, F Wu, L Bansal, E Bradshaw‐Pierce, JR Chan, BM Liederer, ...
CPT: pharmacometrics & systems pharmacology 7 (3), 135-146, 2018
522018
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results
A Margolskee, AS Darwich, X Pepin, L Aarons, A Galetin, ...
European Journal of Pharmaceutical Sciences 96, 610-625, 2017
502017
Spatial heterogeneity in skeletal muscle microvascular blood flow distribution is increased in the metabolic syndrome
JC Frisbee, F Wu, AG Goodwill, JT Butcher, DA Beard
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2011
472011
A database of thermodynamic properties of the reactions of glycolysis, the tricarboxylic acid cycle, and the pentose phosphate pathway
X Li, F Wu, F Qi, DA Beard
Database 2011, 2011
452011
Blood flow in microvascular networks: a study in nonlinear biology
JB Geddes, RT Carr, F Wu, Y Lao, M Maher
Chaos: An Interdisciplinary Journal of Nonlinear Science 20 (4), 045123, 2010
412010
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across …
AS Darwich, A Margolskee, X Pepin, L Aarons, A Galetin, ...
European Journal of Pharmaceutical Sciences 96, 626-642, 2017
382017
Microvascular perfusion heterogeneity contributes to peripheral vascular disease in metabolic syndrome
JC Frisbee, AG Goodwill, SJ Frisbee, JT Butcher, F Wu, PD Chantler
The Journal of physiology 594 (8), 2233-2243, 2016
372016
A database of thermodynamic quantities for the reactions of glycolysis and the tricarboxylic acid cycle
X Li, RK Dash, RK Pradhan, F Qi, M Thompson, KC Vinnakota, F Wu, ...
The Journal of Physical Chemistry B 114 (49), 16068-16082, 2010
362010
Oscillations in a simple microvascular network
RT Carr, JB Geddes, F Wu
Annals of biomedical engineering 33 (6), 764-771, 2005
352005
Roles of the creatine kinase system and myoglobin in maintaining energetic state in the working heart
F Wu, DA Beard
BMC Systems Biology 3 (1), 1-16, 2009
282009
The onset of oscillations in microvascular blood flow
JB Geddes, RT Carr, NJ Karst, F Wu
SIAM Journal on Applied Dynamical Systems 6 (4), 694-727, 2007
282007
Detailed enzyme kinetics in terms of biochemical species: study of citrate synthase
DA Beard, KC Vinnakota, F Wu
PLoS One 3 (3), e1825, 2008
272008
Modeling of cellular metabolism and microcirculatory transport
DA Beard, F Wu, ME Cabrera, RK Dash
Microcirculation 15 (8), 777-793, 2008
262008
Analysis of the kinetics and bistability of ubiquinol: cytochrome c oxidoreductase
JN Bazil, KC Vinnakota, F Wu, DA Beard
Biophysical journal 105 (2), 343-355, 2013
252013
Identification of the kinetic mechanism of succinyl-CoA synthetase
X Li, F Wu, DA Beard
Bioscience reports 33 (1), 2013
252013
Multiple ion binding equilibria, reaction kinetics, and thermodynamics in dynamic models of biochemical pathways
KC Vinnakota, F Wu, MJ Kushmerick, DA Beard
Methods in enzymology 454, 29-68, 2009
242009
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Articles 1–20