| 5'-Triphosphate RNA is the ligand for RIG-I V Hornung, J Ellegast, S Kim, K Brzózka, A Jung, H Kato, H Poeck, ... science 314 (5801), 994-997, 2006 | 3083 | 2006 |
| The C-terminal regulatory domain is the RNA 5′-triphosphate sensor of RIG-I S Cui, K Eisenächer, A Kirchhofer, K Brzózka, A Lammens, K Lammens, ... Molecular cell 29 (2), 169-179, 2008 | 655 | 2008 |
| Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3 K Brzózka, S Finke, KK Conzelmann Journal of virology 79 (12), 7673-7681, 2005 | 395 | 2005 |
| Inhibition of toll-like receptor 7-and 9-mediated alpha/beta interferon production in human plasmacytoid dendritic cells by respiratory syncytial virus and measles virus J Schlender, V Hornung, S Finke, M Günthner-Biller, S Marozin, ... Journal of virology 79 (9), 5507-5515, 2005 | 307 | 2005 |
| Inhibition of interferon signaling by rabies virus phosphoprotein P: activation-dependent binding of STAT1 and STAT2 K Brzózka, S Finke, KK Conzelmann Journal of virology 80 (6), 2675-2683, 2006 | 290 | 2006 |
| Genetic dissection of interferon-antagonistic functions of rabies virus phosphoprotein: inhibition of interferon regulatory factor 3 activation is important for pathogenicity M Rieder, K Brzózka, CK Pfaller, JH Cox, L Stitz, KK Conzelmann Journal of virology 85 (2), 842-852, 2011 | 121 | 2011 |
| Tracking fluorescence-labeled rabies virus: enhanced green fluorescent protein-tagged phosphoprotein P supports virus gene expression and formation of infectious particles S Finke, K Brzózka, KK Conzelmann Journal of virology 78 (22), 12333-12343, 2004 | 103 | 2004 |
| SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains T Rzymski, M Mikula, E Żyłkiewicz, A Dreas, K Wiklik, A Gołas, K Wójcik, ... Oncotarget 8 (20), 33779, 2017 | 83 | 2017 |
| CDK8 kinase—An emerging target in targeted cancer therapy T Rzymski, M Mikula, K Wiklik, K Brzózka Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (10), 1617-1629, 2015 | 79 | 2015 |
| Mitogen-activated protein kinase (MAPK) interacting kinases 1 and 2 (MNK1 and MNK2) as targets for cancer therapy: recent progress in the development of MNK inhibitors A Dreas, M Mikulski, M Milik, CH Fabritius, K Brzózka, T Rzymski Current medicinal chemistry 24 (28), 3025-3053, 2017 | 76 | 2017 |
| MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma Y Zhan, J Guo, W Yang, C Goncalves, T Rzymski, A Dreas, E Żyłkiewicz, ... The Journal of clinical investigation 127 (11), 4179-4192, 2017 | 70 | 2017 |
| Expression of PIM kinases in Reed-Sternberg cells fosters immune privilege and tumor cell survival in Hodgkin lymphoma M Szydłowski, M Prochorec-Sobieszek, A Szumera-Ciećkiewicz, ... Blood, The Journal of the American Society of Hematology 130 (12), 1418-1429, 2017 | 54 | 2017 |
| Serine biosynthesis pathway supports MYC–miR-494–EZH2 feed-forward circuit necessary to maintain metabolic and epigenetic reprogramming of Burkitt Lymphoma Cells E Białopiotrowicz, M Noyszewska-Kania, N Kachamakova-Trojanowska, ... Cancers 12 (3), 580, 2020 | 37 | 2020 |
| A novel, dual pan-PIM/FLT3 inhibitor SEL24 exhibits broad therapeutic potential in acute myeloid leukemia W Czardybon, R Windak, A Gołas, M Gałęzowski, A Sabiniarz, I Dolata, ... Oncotarget 9 (24), 16917, 2018 | 33 | 2018 |
| Development and characterization of a new inhibitor of heme oxygenase activity for cancer treatment O Mucha, P Podkalicka, M Mikulski, S Barwacz, K Andrysiak, A Biela, ... Archives of biochemistry and biophysics 671, 130-142, 2019 | 28 | 2019 |
| Compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine … K Brzózka, W Czardybon, A Sabiniarz, M Millik, R Windak, A Zarebski, ... US Patent 8,604,217, 2013 | 26 | 2013 |
| Inhibition of PIM kinases in DLBCL targets MYC transcriptional program and augments the efficacy of anti-CD20 antibodies M Szydłowski, F Garbicz, E Jabłońska, P Górniak, D Komar, B Pyrzyńska, ... Cancer Research 81 (23), 6029-6043, 2021 | 23 | 2021 |
| Discovery of a series of ester-substituted NLRP3 inflammasome inhibitors D Harrison, N Boutard, K Brzozka, M Bugaj, S Chmielewski, A Cierpich, ... Bioorganic & Medicinal Chemistry Letters 30 (23), 127560, 2020 | 21 | 2020 |
| Synthesis of amide and sulfonamide substituted N-aryl 6-aminoquinoxalines as PFKFB3 inhibitors with improved physicochemical properties N Boutard, A Białas, A Sabiniarz, P Guzik, K Banaszak, A Biela, M Bień, ... Bioorganic & Medicinal Chemistry Letters 29 (4), 646-653, 2019 | 20 | 2019 |
| Microenvironment‐induced PIM kinases promote CXCR 4‐triggered mTOR pathway required for chronic lymphocytic leukaemia cell migration E Białopiotrowicz, P Górniak, M Noyszewska‐Kania, B Puła, ... Journal of cellular and molecular medicine 22 (7), 3548-3559, 2018 | 20 | 2018 |
