Jakub Mieczkowski
Jakub Mieczkowski
International Research Agenda 3P, Medical University of Gdańsk
Verified email at - Homepage
Cited by
Cited by
SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation
X Wang, RS Lee, BH Alver, JR Haswell, S Wang, J Mieczkowski, Y Drier, ...
Nature genetics 49 (2), 289-295, 2017
MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
J Mieczkowski, A Cook, SK Bowman, B Mueller, BH Alver, S Kundu, ...
Nature communications 7 (1), 11485, 2016
Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
N Ochocka, P Segit, KA Walentynowicz, K Wojnicki, S Cyranowski, ...
Nature communications 12 (1), 1151, 2021
The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia
P Przanowski, M Dabrowski, A Ellert-Miklaszewska, M Kloss, ...
Journal of molecular medicine 92, 239-254, 2014
Widespread changes in nucleosome accessibility without changes in nucleosome occupancy during a rapid transcriptional induction
B Mueller, J Mieczkowski, S Kundu, P Wang, R Sadreyev, MY Tolstorukov, ...
Genes & development 31 (5), 451-462, 2017
Enhancer regions show high histone H3. 3 turnover that changes during differentiation
AM Deaton, M Gomez-Rodriguez, J Mieczkowski, MY Tolstorukov, ...
elife 5, e15316, 2016
Immune microenvironment of experimental rat C6 gliomas resembles human glioblastomas
A Gieryng, D Pszczolkowska, K Bocian, M Dabrowski, WD Rajan, M Kloss, ...
Scientific reports 7 (1), 17556, 2017
Novel proteins regulated by mTOR in subependymal giant cell astrocytomas of patients with tuberous sclerosis complex and new therapeutic implications
ME Tyburczy, K Kotulska, P Pokarowski, J Mieczkowski, J Kucharska, ...
The American Journal of Pathology 176 (4), 1878-1890, 2010
Down-regulation of IKKβ expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in glioblastoma
J Mieczkowski, M Kocyk, P Nauman, K Gabrusiewicz, M Sielska, ...
Oncotarget 6 (32), 33077, 2015
Environmental stimuli shape microglial plasticity in glioma
S Garofalo, A Porzia, F Mainiero, S Di Angelantonio, B Cortese, B Basilico, ...
Elife 6, e33415, 2017
In search for reliable markers of glioma-induced polarization of microglia
KA Walentynowicz, N Ochocka, M Pasierbinska, K Wojnicki, K Stepniak, ...
Frontiers in immunology 9, 369842, 2018
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
J Mieczkowski, ME Tyburczy, M Dabrowski, P Pokarowski
BMC bioinformatics 11, 1-10, 2010
Novel small molecular inhibitors disrupt the JAK/STAT3 and FAK signaling pathways and exhibit a potent antitumor activity in glioma cells
K Swiatek-Machado, J Mieczkowski, A Ellert-Miklaszewska, P Swierk, ...
Cancer biology & therapy 13 (8), 657-670, 2012
EGFR/FOXO3a/BIM signaling pathway determines chemosensitivity of BMP4-differentiated glioma stem cells to temozolomide
IA Ciechomska, B Gielniewski, B Wojtas, B Kaminska, J Mieczkowski
Experimental & molecular medicine 52 (8), 1326-1340, 2020
Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells
J Ulanska-Poutanen, J Mieczkowski, C Zhao, K Konarzewska, B Kaza, ...
Elife 7, e30325, 2018
Search for novel STAT3-dependent genes reveals SERPINA3 as a new STAT3 target that regulates invasion of human melanoma cells
DW Kulesza, K Ramji, M Maleszewska, J Mieczkowski, M Dabrowski, ...
Laboratory Investigation 99 (11), 1607-1621, 2019
Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas
K Stępniak, MA Machnicka, J Mieczkowski, A Macioszek, B Wojtaś, ...
Nature Communications 12 (1), 3621, 2021
Identification of pathway deregulation–gene expression based analysis of consistent signal transduction
J Mieczkowski, K Swiatek-Machado, B Kaminska
PLoS One 7 (7), e41541, 2012
Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells
M Kruczyk, P Przanowski, M Dabrowski, K Swiatek-Machado, ...
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (11 …, 2014
Emerging advances in combinatorial treatments of epigenetically altered pediatric high-grade H3K27M gliomas
KB Leszczynska, C Jayaprakash, B Kaminska, J Mieczkowski
Frontiers in Genetics 12, 742561, 2021
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