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Hisham Qosa
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Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer’s disease: In vitro and in vivo studies
AH Abuznait, H Qosa, BA Busnena, KA El Sayed, A Kaddoumi
ACS chemical neuroscience 4 (6), 973-982, 2013
2972013
Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders
H Qosa, DS Miller, P Pasinelli, D Trotti
Brain research 1628, 298-316, 2015
2382015
Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease
H Qosa, AH Abuznait, RA Hill, A Kaddoumi
Journal of Alzheimer's Disease 31 (1), 151-165, 2012
1942012
Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier model
H Qosa, YS Batarseh, MM Mohyeldin, KA El Sayed, JN Keller, ...
ACS chemical neuroscience 6 (11), 1849-1859, 2015
1512015
Differences in amyloid-β clearance across mouse and human blood–brain barrier models: kinetic analysis and mechanistic modeling
H Qosa, BS Abuasal, IA Romero, B Weksler, PO Couraud, JN Keller, ...
Neuropharmacology 79, 668-678, 2014
1462014
Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice
H Qosa, LA Mohamed, YS Batarseh, S Alqahtani, B Ibrahim, H LeVine III, ...
The Journal of Nutritional Biochemistry 26 (12), 1479-1490, 2015
972015
Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood–brain …
H Qosa, H LeVine III, JN Keller, A Kaddoumi
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (9 …, 2014
712014
Allele and genotype frequencies of the polymorphic cytochrome P450 genes (CYP1A1, CYP3A4, CYP3A5, CYP2C9 and CYP2C19) in the Jordanian population
AM Yousef, NR Bulatova, W Newman, N Hakooz, S Ismail, H Qusa, ...
Molecular biology reports 39, 9423-9433, 2012
662012
Astrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P‐Glycoprotein) in endothelial cells of the blood–brain barrier in mutant superoxide dismutase 1 …
H Qosa, J Lichter, M Sarlo, SS Markandaiah, K McAvoy, JP Richard, ...
Glia 64 (8), 1298-1313, 2016
642016
Age-related decline in brain and hepatic clearance of amyloid-beta is rectified by the cholinesterase inhibitors donepezil and rivastigmine in rats
LA Mohamed, H Qosa, A Kaddoumi
ACS chemical neuroscience 6 (5), 725-736, 2015
592015
High-throughput screening for identification of blood-brain barrier integrity enhancers: a drug repurposing opportunity to rectify vascular amyloid toxicity
H Qosa, LA Mohamed, SB Al Rihani, YS Batarseh, QV Duong, JN Keller, ...
Journal of Alzheimer's Disease 53 (4), 1499-1516, 2016
532016
FDA Approval Summary: Gilteritinib for Relapsed or Refractory Acute Myeloid Leukemia with a FLT3 Mutation
ED Pulte, KJ Norsworthy, Y Wang, Q Xu, H Qosa, R Gudi, D Przepiorka, ...
Clinical Cancer Research 27 (13), 3515-3521, 2021
522021
Comparison of the intestinal absorption and bioavailability of γ‐tocotrienol and α‐tocopherol: in vitro, in situ and in vivo studies
BS Abuasal, H Qosa, PW Sylvester, A Kaddoumi
Biopharmaceutics & drug disposition 33 (5), 246-256, 2012
512012
Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products
AH Abuznait, H Qosa, ND O’Connell, J Akbarian-Tefaghi, PW Sylvester, ...
Food and chemical toxicology 49 (11), 2765-2772, 2011
432011
In vitro UGT1A1 inhibition by tyrosine kinase inhibitors and association with drug-induced hyperbilirubinemia
H Qosa, BR Avaritt, NR Hartman, DA Volpe
Cancer chemotherapy and pharmacology 82, 795-802, 2018
362018
FDA approval summary: nivolumab in combination with ipilimumab for the treatment of unresectable malignant pleural mesothelioma
EC Nakajima, PJ Vellanki, E Larkins, S Chatterjee, PS Mishra-Kalyani, ...
Clinical Cancer Research 28 (3), 446-451, 2022
352022
Transporters as drug targets in neurological diseases
H Qosa, LA Mohamed, S Alqahtani, BS Abuasal, RA Hill, A Kaddoumi
Clinical Pharmacology & Therapeutics 100 (5), 441-453, 2016
342016
Adverse effects of tacrolimus in renal transplant patients from living donors
N Bulatova, AM Yousef, G Al-Khayyat, H Qosa
Current drug safety 6 (1), 3-11, 2011
332011
Orlistat limits cholesterol intestinal absorption by Niemann-pick C1-like 1 (NPC1L1) inhibition
S Alqahtani, H Qosa, B Primeaux, A Kaddoumi
European journal of pharmacology 762, 263-269, 2015
292015
Effect of mouse strain as a background for Alzheimer’s disease models on the clearance of amyloid-β
H Qosa, A Kaddoumi
Journal of systems and integrative neuroscience 2 (2), 135, 2016
192016
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