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Madhuri Chattopadhyay
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The octarepeat domain of the prion protein binds Cu (II) with three distinct coordination modes at pH 7.4
M Chattopadhyay, ED Walter, DJ Newell, PJ Jackson, E Aronoff-Spencer, ...
Journal of the American Chemical Society 127 (36), 12647-12656, 2005
2522005
Initiation and elongation in fibrillation of ALS-linked superoxide dismutase
M Chattopadhyay, A Durazo, SH Sohn, CD Strong, EB Gralla, ...
Proceedings of the National Academy of Sciences 105 (48), 18663-18668, 2008
2472008
Aggregation of copper–zinc superoxide dismutase in familial and sporadic ALS
M Chattopadhyay, JS Valentine
Antioxidants & redox signaling 11 (7), 1603-1614, 2009
1892009
IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patients
M Fiala, M Chattopadhay, A La Cava, E Tse, G Liu, E Lourenco, A Eskin, ...
J Neuroinflammation 7, 76, 2010
1682010
The affinity of copper binding to the prion protein octarepeat domain: evidence for negative cooperativity
ED Walter, M Chattopadhyay, GL Millhauser
Biochemistry 45 (43), 13083-13092, 2006
1542006
Copper and zinc metallation status of copper-zinc superoxide dismutase from amyotrophic lateral sclerosis transgenic mice
HL Lelie, A Liba, MW Bourassa, M Chattopadhyay, PK Chan, EB Gralla, ...
Journal of Biological Chemistry 286 (4), 2795-2806, 2011
1372011
SOD1 aggregation and ALS: role of metallation states and disulfide status.
Y Sheng, M Chattopadhyay, J Whitelegge, JS Valentine.
Curr Top Med Chem, 2013
1052013
Neuronal phagocytosis by inflammatory macrophages in ALS spinal cord: inhibition of inflammation by resolvin D1
G Liu, M Fiala, MT Mizwicki, J Sayre, L Magpantay, A Siani, M Mahanian, ...
American journal of neurodegenerative disease 1 (1), 60, 2012
822012
Tocilizumab attenuates inflammation in ALS patients through inhibition of IL6 receptor signaling
MT Mizwicki, M Fiala, L Magpantay, N Aziz, J Sayre, G Liu, A Siani, ...
American journal of neurodegenerative disease 1 (3), 305, 2012
712012
The disulfide bond, but not zinc or dimerization, controls initiation and seeded growth in amyotrophic lateral sclerosis-linked Cu, Zn superoxide dismutase (SOD1) fibrillation
M Chattopadhyay, E Nwadibia, CD Strong, EB Gralla, JS Valentine, ...
Journal of Biological Chemistry 290 (51), 30624-30636, 2015
562015
Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy
PK Chan, M Chattopadhyay, S Sharma, P Souda, EB Gralla, DR Borchelt, ...
Proceedings of the National Academy of Sciences 110 (27), 10934-10939, 2013
512013
Electron spin relaxation of copper (II) complexes in glassy solution between 10 and 120 K
AJ Fielding, S Fox, GL Millhauser, M Chattopadhyay, PMH Kroneck, ...
Journal of Magnetic Resonance 179 (1), 92-104, 2006
482006
Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded β-barrel at physiological temperature
A Durazo, BF Shaw, M Chattopadhyay, KF Faull, AM Nersissian, ...
Journal of Biological Chemistry 284 (49), 34382-34389, 2009
462009
Probing the role of PrP repeats in conformational conversion and amyloid assembly of chimeric yeast prions
J Dong, JD Bloom, V Goncharov, M Chattopadhyay, GL Millhauser, ...
Journal of Biological Chemistry 282 (47), 34204-34212, 2007
392007
Nanoengineered analytical immobilized metal affinity chromatography stationary phase by atom transfer radical polymerization: Separation of synthetic prion peptides
P McCarthy, M Chattopadhyay, GL Millhauser, NV Tsarevsky, ...
Analytical biochemistry 366 (1), 1-8, 2007
292007
VE-1902—A direct thrombin inhibitor with reversible covalent mechanism of action shows efficacy with reduced bleeding in rodent models of thrombosis
M Sivaraja, DM Clemens, S Sizikov, S Dash, C Xu, M Rienzo, B Yang, ...
Thrombosis research 190, 112-121, 2020
52020
Metal-free superoxide dismutase-1 and three different ALS variants share a similar partially unfolded {beta}-barrel at physiological temperature
A Durazo, BF Shaw, M Chattopadhyay, KF Faull, AM Nersissian, ...
J Biol Chem 284, 34382-34389, 2009
52009
Copper and Zinc Metallation Status of Copper Zinc Superoxide Dismutase form Amyotrophic Lateral Sclerosis Transgenic Mice
HL Lelie, L Miller, A Liba, MW Bourassa, M Chattopadhyay, PK Chan, ...
The Journal of Biological Chemistry 286 (BNL-94908-2011-JA), 2010
12010
Abstract TMP98: A New Class of Precision Oral Anticoagulants (proacs) That Mostly Preserves Platelet Activity in vitro and in vivo
M Sivaraja, D Clemens, S Sizikov, C Xu, B Yang, L Igoudin, ...
Stroke 50 (Suppl_1), ATMP98-ATMP98, 2019
2019
Potent cell cycle inhibitors suitable for treatment of multidrug-resistant tumors
M Sivaraja, S Sizikov, N Sirisoma, T Kirtadze, M Chattopadhyay, M Ewald, ...
Cancer Research 78 (13_Supplement), 4851-4851, 2018
2018
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