Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing KA Birdwell, B Decker, JM Barbarino, JF Peterson, CM Stein, W Sadee, ... Clinical Pharmacology & Therapeutics 98 (1), 19-24, 2015 | 702 | 2015 |
Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C> T affects mRNA stability D Wang, AD Johnson, AC Papp, DL Kroetz, W Sadee Pharmacogenetics and genomics 15 (10), 693-704, 2005 | 645 | 2005 |
Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G Y Zhang, D Wang, AD Johnson, AC Papp, W Sadée Journal of Biological Chemistry 280 (38), 32618-32624, 2005 | 636 | 2005 |
Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs D Wang, Y Guo, SA Wrighton, GE Cooke, W Sadee The pharmacogenomics journal 11 (4), 274-286, 2011 | 608 | 2011 |
Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory Y Zhang, A Bertolino, L Fazio, G Blasi, A Rampino, R Romano, MLT Lee, ... Proceedings of the National Academy of Sciences 104 (51), 20552-20557, 2007 | 508 | 2007 |
Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement D Wang, H Chen, KM Momary, LH Cavallari, JA Johnson, W Sadée Blood, The Journal of the American Society of Hematology 112 (4), 1013-1021, 2008 | 238 | 2008 |
Opioid receptor homo-and heterodimerization in living cells by quantitative bioluminescence resonance energy transfer D Wang, X Sun, LM Bohn, W Sadee Molecular pharmacology 67 (6), 2173-2184, 2005 | 227 | 2005 |
Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia A Bertolino, L Fazio, G Caforio, G Blasi, A Rampino, R Romano, ... Brain 132 (2), 417-425, 2009 | 184 | 2009 |
Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse RA Moyer, D Wang, AC Papp, RM Smith, L Duque, DC Mash, W Sadee Neuropsychopharmacology 36 (4), 753-762, 2011 | 170 | 2011 |
μ-Opioid receptor-mediated ERK activation involves calmodulin-dependent epidermal growth factor receptor transactivation MM Belcheva, M Szùcs, D Wang, W Sadee, CJ Coscia Journal of Biological Chemistry 276 (36), 33847-33853, 2001 | 168 | 2001 |
Calmodulin binding to G protein-coupling domain of opioid receptors D Wang, W Sadée, JM Quillan Journal of Biological Chemistry 274 (31), 22081-22088, 1999 | 162 | 1999 |
Searching for polymorphisms that affect gene expression and mRNA processing: example ABCB1 (MDR1) D Wang, W Sadée The AAPS journal 8, E515-E520, 2006 | 159 | 2006 |
Inverse agonists and neutral antagonists at µ opioid receptor (MOR): possible role of basal receptor signaling in narcotic dependence D Wang, KM Raehal, EJ Bilsky, W Sadée Journal of neurochemistry 77 (6), 1590-1600, 2001 | 157 | 2001 |
Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity D Wang, MJ Poi, X Sun, A Gaedigk, JS Leeder, W Sadee Human molecular genetics 23 (1), 268-278, 2014 | 127 | 2014 |
Different effects of opioid antagonists on μ-, δ-, and κ-opioid receptors with and without agonist pretreatment D Wang, X Sun, W Sadee Journal of Pharmacology and Experimental Therapeutics 321 (2), 544-552, 2007 | 127 | 2007 |
Basal opioid receptor activity, neutral antagonists, and therapeutic opportunities W Sadée, D Wang, EJ Bilsky Life sciences 76 (13), 1427-1437, 2005 | 119 | 2005 |
Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics AD Johnson, D Wang, W Sadee Pharmacology & therapeutics 106 (1), 19-38, 2005 | 113 | 2005 |
G-protein coupling of μ-opioid receptors (OP3): elevated basal signalling activity NT Burford, D Wang, W Sadée Biochemical Journal 348 (3), 531-537, 2000 | 113 | 2000 |
Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues AD Johnson, Y Zhang, AC Papp, JK Pinsonneault, JE Lim, D Saffen, Z Dai, ... Pharmacogenetics and genomics 18 (9), 781-791, 2008 | 111 | 2008 |
Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy W Sadee, D Wang, AC Papp, JK Pinsonneault, RM Smith, RA Moyer, ... Clinical Pharmacology & Therapeutics 89 (3), 355-365, 2011 | 110 | 2011 |