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Bradley Spicer
Bradley Spicer
Verified email at monash.edu
Title
Cited by
Cited by
Year
Conformational changes during pore formation by the perforin-related protein pleurotolysin
N Lukoyanova, SC Kondos, I Farabella, RHP Law, CF Reboul, ...
PLoS biology 13 (2), e1002049, 2015
1392015
Structure of the poly-C9 component of the complement membrane attack complex
NV Dudkina, BA Spicer, CF Reboul, PJ Conroy, N Lukoyanova, ...
Nature communications 7 (1), 10588, 2016
1252016
The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1
SS Pang, C Bayly-Jones, M Radjainia, BA Spicer, RHP Law, AW Hodel, ...
Nature communications 10 (1), 4288, 2019
642019
The first transmembrane region of complement component-9 acts as a brake on its self-assembly
BA Spicer, RHP Law, TT Caradoc-Davies, SM Ekkel, C Bayly-Jones, ...
Nature Communications 9 (1), 3266, 2018
512018
Delivery of femtolitre droplets using surface acoustic wave based atomisation for cryo-EM grid preparation
D Ashtiani, H Venugopal, M Belousoff, B Spicer, J Mak, A Neild, ...
Journal of structural biology 203 (2), 94-101, 2018
392018
Perforin—A key (shaped) weapon in the immunological arsenal
BA Spicer, PJ Conroy, RHP Law, I Voskoboinik, JC Whisstock
Seminars in cell & developmental biology 72, 117-123, 2017
352017
Evaluation of serum glycoprotein biomarker candidates for detection of esophageal adenocarcinoma and surveillance of barrett's esophagus
AK Shah, G Hartel, I Brown, C Winterford, R Na, KA Le Cao, BA Spicer, ...
Molecular & Cellular Proteomics 17 (12), 2324-2334, 2018
262018
Ancient but not forgotten: new insights into MPEG1, a macrophage perforin-like immune effector
C Bayly-Jones, SS Pang, BA Spicer, JC Whisstock, MA Dunstone
Frontiers in Immunology 11, 581906, 2020
212020
Branching out the aerolysin, ETX/MTX-2 and Toxin_10 family of pore forming proteins
CJ Lacomel, MA Dunstone, BA Spicer
Journal of Invertebrate Pathology 186, 107570, 2021
132021
Going full circle: determining the structures of complement component 9
BA Spicer, MA Dunstone
Methods in Enzymology 649, 103-123, 2021
42021
The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
C Bayly-Jones, BHT Ho, C Lau, EWW Leung, L D’Andrea, CJ Lupton, ...
Communications Biology 6 (1), 42, 2023
32023
160 CD59, C9-lock and horse C9 all inhibit MAC assembly through similar mechanisms
W Zelek, B Spicer, R Harrison, M Dunstone, P Morgan
Immunobiology 228 (5), 152610, 2023
2023
Mechanism of inhibition of membrane attack complex by disulphide-locked C9
W Zelek, BA Spicer, MA Dunstone, BP Morgan
MOLECULAR IMMUNOLOGY 141, 198-198, 2022
2022
A biochemical characterisation of the MACPF/CDC pore assembly
BA SPICER
Monash University, 2018
2018
Protein conformation of C9 controls the final membrane complex assembly
BAC Spicer, C Bayly-Jones, RHP Law, TT Caradox-Davies, PJ Conroy, ...
Society of Crystallographers in Australia and New Zealand, 2017
2017
How do MACPF/CDC pore forming protein punch holes in cells?
M Dunstone, B Spicer, SS Pang, C Bayly-Jones, J Whisstock
Acta Crystallographica Section A: Foundations and Advances 73, C832-C832, 2017
2017
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