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Mohamed (Mo) Akl, Ph.D, MBA
Mohamed (Mo) Akl, Ph.D, MBA
Parexel/ Pfizer
Verified email at pfizer.com - Homepage
Title
Cited by
Cited by
Year
Molecular and clinical significance of fibroblast growth factor 2 (FGF2/bFGF) in malignancies of solid and hematological cancers for personalized therapies
MR Akl, P Nagpal, NM Ayoub, B Tai, SA Prabhu, CM Capac, M Gliksman, ...
Oncotarget 7 (28), 44735, 2016
1892016
Olive phenolics as c-Met inhibitors:(-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models
MR Akl, NM Ayoub, MM Mohyeldin, BA Busnena, AI Foudah, YY Liu, ...
PloS one 9 (5), e97622, 2014
1352014
Evaluation of cytotoxic compounds from Calligonum comosum L. growing in Egypt
FA Badria, M Ameen, MR Akl
Zeitschrift für Naturforschung C 62 (9-10), 656-660, 2007
1192007
Molecular and clinical profiles of syndecan-1 in solid and hematological cancer for prognosis and precision medicine
MR Akl, P Nagpal, NM Ayoub, SA Prabhu, M Gliksman, B Tai, A Hatipoglu, ...
Oncotarget 6 (30), 28693, 2015
892015
Olive oil‐derived oleocanthal as potent inhibitor of mammalian target of rapamycin: biological evaluation and molecular modeling studies
MA Khanfar, SK Bardaweel, MR Akl, KA El Sayed
Phytotherapy research 29 (11), 1776-1782, 2015
732015
Potential role of tocotrienols in the treatment and prevention of breast cancer
PW Sylvester, MR Akl, A Malaviya, P Parajuli, S Ananthula, RV Tiwari, ...
Biofactors 40 (1), 49-58, 2014
592014
Sesamin synergistically potentiates the anticancer effects of γ-tocotrienol in mammary cancer cell lines
MR Akl, NM Ayoub, BS Abuasal, A Kaddoumi, PW Sylvester
Fitoterapia 84, 347-359, 2013
572013
Norstictic Acid Inhibits Breast Cancer Cell Proliferation, Migration, Invasion, and In Vivo Invasive Growth Through Targeting C‐Met
HY Ebrahim, HE Elsayed, MM Mohyeldin, MR Akl, J Bhattacharjee, ...
Phytotherapy Research 30 (4), 557-566, 2016
552016
Pediatric Hodgkin lymphoma–biomarkers, drugs, and clinical trials for translational science and medicine
P Nagpal, MR Akl, NM Ayoub, T Tomiyama, T Cousins, B Tai, N Carroll, ...
Oncotarget 7 (41), 67551, 2016
472016
Araguspongine C induces autophagic death in breast cancer cells through suppression of c-Met and HER2 receptor tyrosine kinase signaling
MR Akl, NM Ayoub, HY Ebrahim, MM Mohyeldin, KY Orabi, AI Foudah, ...
Marine drugs 13 (1), 288-311, 2015
462015
Tocotrienol combination therapy results in synergistic anticancer response
PW Sylvester, VB Wali, SV Bachawal, AB Shirode, NM Ayoub, MR Akl
Front Biosci 17, 3183-3195, 2011
462011
Mechanisms mediating the synergistic anticancer effects of combined γ-tocotrienol and sesamin treatment
MR Akl, NM Ayoub, PW Sylvester
Planta medica, 1731-1739, 2012
452012
Redox-silent tocotrienol esters as breast cancer proliferation and migration inhibitors
FA Behery, AY Elnagar, MR Akl, VB Wali, B Abuasal, A Kaddoumi, ...
Bioorganic & medicinal chemistry 18 (22), 8066-8075, 2010
442010
Discovery, optimization, and pharmacophore modeling of oleanolic acid and analogues as breast cancer cell migration and invasion inhibitors through targeting Brk/Paxillin/Rac1 axis
HE Elsayed, MR Akl, HY Ebrahim, AA Sallam, EG Haggag, AM Kamal, ...
Chemical biology & drug design 85 (2), 231-243, 2015
322015
3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells
MR Akl, HE Elsayed, HY Ebrahim, EG Haggag, AM Kamal, KA El Sayed
European Journal of Pharmacology 740, 209-217, 2014
322014
(−)-Oleocanthal combined with lapatinib treatment synergized against HER-2 positive breast cancer in vitro and in vivo
AB Siddique, HY Ebrahim, MR Akl, NM Ayoub, AA Goda, MM Mohyeldin, ...
Nutrients 11 (2), 412, 2019
302019
Combined γ‐tocotrienol and Met inhibitor treatment suppresses mammary cancer cell proliferation, epithelial‐to‐mesenchymal transition and migration
NM Ayoub, MR Akl, PW Sylvester
Cell Proliferation 46 (5), 538-553, 2013
302013
Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling
AA Sallam, MM Mohyeldin, AI Foudah, MR Akl, S Nazzal, SA Meyer, ...
Organic & biomolecular chemistry 12 (28), 5295-5303, 2014
282014
Optimization of tocotrienols as antiproliferative and antimigratory leads
FA Behery, MR Akl, S Ananthula, P Parajuli, PW Sylvester, KA El Sayed
European journal of medicinal chemistry 59, 329-341, 2013
272013
Usnic acid benzylidene analogues as potent mechanistic target of rapamycin inhibitors for the control of breast malignancies
HY Ebrahim, MR Akl, HE Elsayed, RA Hill, KA El Sayed
Journal of natural products 80 (4), 932-952, 2017
262017
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Articles 1–20