Molecular and clinical significance of fibroblast growth factor 2 (FGF2/bFGF) in malignancies of solid and hematological cancers for personalized therapies MR Akl, P Nagpal, NM Ayoub, B Tai, SA Prabhu, CM Capac, M Gliksman, ... Oncotarget 7 (28), 44735, 2016 | 189 | 2016 |
Olive phenolics as c-Met inhibitors:(-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models MR Akl, NM Ayoub, MM Mohyeldin, BA Busnena, AI Foudah, YY Liu, ... PloS one 9 (5), e97622, 2014 | 135 | 2014 |
Evaluation of cytotoxic compounds from Calligonum comosum L. growing in Egypt FA Badria, M Ameen, MR Akl Zeitschrift für Naturforschung C 62 (9-10), 656-660, 2007 | 119 | 2007 |
Molecular and clinical profiles of syndecan-1 in solid and hematological cancer for prognosis and precision medicine MR Akl, P Nagpal, NM Ayoub, SA Prabhu, M Gliksman, B Tai, A Hatipoglu, ... Oncotarget 6 (30), 28693, 2015 | 89 | 2015 |
Olive oil‐derived oleocanthal as potent inhibitor of mammalian target of rapamycin: biological evaluation and molecular modeling studies MA Khanfar, SK Bardaweel, MR Akl, KA El Sayed Phytotherapy research 29 (11), 1776-1782, 2015 | 73 | 2015 |
Potential role of tocotrienols in the treatment and prevention of breast cancer PW Sylvester, MR Akl, A Malaviya, P Parajuli, S Ananthula, RV Tiwari, ... Biofactors 40 (1), 49-58, 2014 | 59 | 2014 |
Sesamin synergistically potentiates the anticancer effects of γ-tocotrienol in mammary cancer cell lines MR Akl, NM Ayoub, BS Abuasal, A Kaddoumi, PW Sylvester Fitoterapia 84, 347-359, 2013 | 57 | 2013 |
Norstictic Acid Inhibits Breast Cancer Cell Proliferation, Migration, Invasion, and In Vivo Invasive Growth Through Targeting C‐Met HY Ebrahim, HE Elsayed, MM Mohyeldin, MR Akl, J Bhattacharjee, ... Phytotherapy Research 30 (4), 557-566, 2016 | 55 | 2016 |
Pediatric Hodgkin lymphoma–biomarkers, drugs, and clinical trials for translational science and medicine P Nagpal, MR Akl, NM Ayoub, T Tomiyama, T Cousins, B Tai, N Carroll, ... Oncotarget 7 (41), 67551, 2016 | 47 | 2016 |
Araguspongine C induces autophagic death in breast cancer cells through suppression of c-Met and HER2 receptor tyrosine kinase signaling MR Akl, NM Ayoub, HY Ebrahim, MM Mohyeldin, KY Orabi, AI Foudah, ... Marine drugs 13 (1), 288-311, 2015 | 46 | 2015 |
Tocotrienol combination therapy results in synergistic anticancer response PW Sylvester, VB Wali, SV Bachawal, AB Shirode, NM Ayoub, MR Akl Front Biosci 17, 3183-3195, 2011 | 46 | 2011 |
Mechanisms mediating the synergistic anticancer effects of combined γ-tocotrienol and sesamin treatment MR Akl, NM Ayoub, PW Sylvester Planta medica, 1731-1739, 2012 | 45 | 2012 |
Redox-silent tocotrienol esters as breast cancer proliferation and migration inhibitors FA Behery, AY Elnagar, MR Akl, VB Wali, B Abuasal, A Kaddoumi, ... Bioorganic & medicinal chemistry 18 (22), 8066-8075, 2010 | 44 | 2010 |
Discovery, optimization, and pharmacophore modeling of oleanolic acid and analogues as breast cancer cell migration and invasion inhibitors through targeting Brk/Paxillin/Rac1 axis HE Elsayed, MR Akl, HY Ebrahim, AA Sallam, EG Haggag, AM Kamal, ... Chemical biology & drug design 85 (2), 231-243, 2015 | 32 | 2015 |
3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells MR Akl, HE Elsayed, HY Ebrahim, EG Haggag, AM Kamal, KA El Sayed European Journal of Pharmacology 740, 209-217, 2014 | 32 | 2014 |
(−)-Oleocanthal combined with lapatinib treatment synergized against HER-2 positive breast cancer in vitro and in vivo AB Siddique, HY Ebrahim, MR Akl, NM Ayoub, AA Goda, MM Mohyeldin, ... Nutrients 11 (2), 412, 2019 | 30 | 2019 |
Combined γ‐tocotrienol and Met inhibitor treatment suppresses mammary cancer cell proliferation, epithelial‐to‐mesenchymal transition and migration NM Ayoub, MR Akl, PW Sylvester Cell Proliferation 46 (5), 538-553, 2013 | 30 | 2013 |
Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling AA Sallam, MM Mohyeldin, AI Foudah, MR Akl, S Nazzal, SA Meyer, ... Organic & biomolecular chemistry 12 (28), 5295-5303, 2014 | 28 | 2014 |
Optimization of tocotrienols as antiproliferative and antimigratory leads FA Behery, MR Akl, S Ananthula, P Parajuli, PW Sylvester, KA El Sayed European journal of medicinal chemistry 59, 329-341, 2013 | 27 | 2013 |
Usnic acid benzylidene analogues as potent mechanistic target of rapamycin inhibitors for the control of breast malignancies HY Ebrahim, MR Akl, HE Elsayed, RA Hill, KA El Sayed Journal of natural products 80 (4), 932-952, 2017 | 26 | 2017 |