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Emmett M. Leddin
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Year
Advances in Protein Chemistry and Structural Biology
EM Leddin, GA Cisneros
Elsevier, 2019
382019
The impact of inflammation-induced tumor plasticity during myeloid transformation
A Yeaton, G Cayanan, S Loghavi, I Dolgalev, EM Leddin, CE Loo, ...
Cancer Discovery 12 (10), 2392-2413, 2022
352022
Selectivity and Promiscuity in TET-Mediated Oxidation of 5-Methylcytosine in DNA and RNA
JE DeNizio, MY Liu, EM Leddin, GA Cisneros, RM Kohli
Biochemistry 58 (5), 411-421, 2018
352018
Characterization of nine cancer-associated variants in human DNA polymerase κ
NM Antczak, AR Walker, HR Stern, EM Leddin, C Palad, TA Coulther, ...
Chemical research in toxicology 31 (8), 697-711, 2018
102018
Impact of Remdesivir Incorporation along the Primer Strand on SARS-CoV-2 RNA-Dependent RNA Polymerase
S Naseem-Khan, MB Berger, EM Leddin, Y Maghsoud, GA Cisneros
Journal of Chemical Information and Modeling 62 (10), 2456-2465, 2022
92022
Combining Evolutionary Conservation and Quantum Topological Analyses To Determine Quantum Mechanics Subsystems for Biomolecular Quantum Mechanics/Molecular Mechanics Simulations
MA Hix, EM Leddin, GA Cisneros
Journal of Chemical Theory and Computation 17 (7), 4524-4537, 2021
82021
Comparison of DNA and RNA substrate effects on TET2 structure
EM Leddin, GA Cisneros
Advances in Protein Chemistry and Structural Biology 117, 91-112, 2019
52019
Population-based analysis of POT1 variants in a cutaneous melanoma case–control cohort
I Simonin-Wilmer, R Ossio, EM Leddin, M Harland, KA Pooley, ...
Journal of Medical Genetics 60 (7), 692-696, 2023
42023
Computational Compensatory Mutation Discovery Approach: Predicting a PARP1 Variant Rescue Mutation
K Ravishankar, X Jiang, EM Leddin, F Morcos, GA Cisneros
bioRxiv, 2021
42021
Computational drug discovery of an inhibitor of APOBEC3B as a treatment for epithelial cancers
DA Caputa, QP Blankenship, ZD Smith, MM Huebner, ZA Vetter, ...
Journal of Biomolecular Structure and Dynamics, 1-14, 2023
2023
Computational investigation of single nucleotide polymorphisms in human DNA polymerase kappa
E Leddin, A Walker, N Antczak, H Stern, C Palad, T Coulther, R Swett, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Computational investigation of TET2 activity on RNA-containing substrates
E Leddin, J DeNizio, M Liu, R Kohli, G Cisneros
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Computational investigation of cancer-related single nucleotide polymorphisms in TET2
P Camacho, E Leddin, G Cisneros
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
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