A map of human genome variation from population scale sequencing 1000 Genomes Project Consortium Nature 467 (7319), 1061, 2010 | 8760 | 2010 |
Demographic history and rare allele sharing among human populations S Gravel, BM Henn, RN Gutenkunst, AR Indap, GT Marth, AG Clark, F Yu, ... Proceedings of the National Academy of Sciences 108 (29), 11983-11988, 2011 | 707 | 2011 |
Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis KM Backus, HI Boshoff, CS Barry, O Boutureira, MK Patel, F D'hooge, ... Nature chemical biology 7 (4), 228-235, 2011 | 242 | 2011 |
Mechanistic and structural analysis of a family 31 α-glycosidase and its glycosyl-enzyme intermediate AL Lovering, SS Lee, YW Kim, SG Withers, NCJ Strynadka Journal of Biological Chemistry 280 (3), 2105-2115, 2005 | 217 | 2005 |
Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase SS Lee, SY Hong, JC Errey, A Izumi, GJ Davies, BG Davis Nature chemical biology 7 (9), 631-638, 2011 | 206 | 2011 |
Directed evolution of a glycosynthase from Agrobacterium sp. increases its catalytic activity dramatically and expands its substrate repertoire YW Kim, SS Lee, RAJ Warren, SG Withers Journal of Biological Chemistry 279 (41), 42787-42793, 2004 | 171 | 2004 |
Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors JC Errey, SS Lee, RP Gibson, C Martinez Fleites, CS Barry, PMJ Jung, ... Angewandte Chemie International Edition 49 (7), 1234-1237, 2010 | 118 | 2010 |
Composition and pharmaceutical dosage form for colonic drug delivery using polysaccharides SS Lee, CB Lim, CM Pai, S Lee, I Park, MG Seo, H Park US Patent 6,413,494, 2002 | 91 | 2002 |
Biosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediates FJ Wyszynski, SS Lee, T Yabe, H Wang, JP Gomez-Escribano, MJ Bibb, ... Nature chemistry 4 (7), 539-546, 2012 | 82 | 2012 |
Detailed dissection of a new mechanism for glycoside cleavage: α-1, 4-glucan lyase SS Lee, S Yu, SG Withers Biochemistry 42 (44), 13081-13090, 2003 | 81 | 2003 |
ABX-EGF in combination with paclitaxel and carboplatin for advanced non-small cell lung cancer (NSCLC) J Crawford, AB Sandler, LA Hammond, J Schiller, C Belani, M Kozloff, ... Journal of Clinical Oncology 22 (14_suppl), 7083-7083, 2004 | 74 | 2004 |
Identification of the catalytic nucleophile of the Family 31 α-glucosidase from Aspergillus niger via trapping of a 5-fluoroglycosyl–enzyme intermediate SS Lee, S He, SG Withers Biochemical Journal 359 (2), 381-386, 2001 | 66 | 2001 |
Duration of second complete remission compared with first complete remission in patients with acute myeloid leukemia S Lee, MS Tallman, MM Oken, PA Cassileth, JM Bennett, PH Wiernik, ... Leukemia 14 (8), 1345-1348, 2000 | 41 | 2000 |
α-1, 4-Glucan lyase performs a trans-elimination via a nucleophilic displacement followed by a syn-elimination SS Lee, S Yu, SG Withers Journal of the American Chemical Society 124 (18), 4948-4949, 2002 | 39 | 2002 |
Interferon alfa-induced autoimmunity and serum S100 levels as predictive and prognostic biomarkers in high-risk melanoma in the ECOG-intergroup phase II trial E2696 JJ Stuckert, AA Tarhini, S Lee, C Sander, JM Kirkwood Journal of Clinical Oncology 25 (18_suppl), 8506-8506, 2007 | 32 | 2007 |
Structural, mechanistic, and computational analysis of the effects of anomeric fluorines on anomeric fluoride departure in 5-fluoroxylosyl fluorides SS Lee, IR Greig, DJ Vocadlo, JD McCarter, BO Patrick, SG Withers Journal of the American Chemical Society 133 (40), 15826-15829, 2011 | 28 | 2011 |
Phase II study of carboplatin in blast crisis of chronic myeloid leukemia: Eastern Cooperative Oncology Group Study E1992 JP Dutcher, S Lee, E Paietta, JM Bennett, JA Stewart, PH Wiernik Leukemia 12 (7), 1037-1040, 1998 | 25 | 1998 |
Clostridium difficile plasmid isolation as an epidemiologic tool C Clabots, S Lee, D Gerding, M Mulligan, R Kwok, D Schaberg, R Fekety, ... European Journal of Clinical Microbiology and Infectious Diseases 7, 312-315, 1988 | 24 | 1988 |
Eastern Cooperative Oncology Group Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with … MB Atkins, J Hsu, S Lee, GI Cohen, LE Flaherty, JA Sosman, VK Sondak, ... J Clin Oncol 26 (35), 5748-5754, 2008 | 20 | 2008 |
E1696: Final analysis of the clinical and immunological results of a multicenter ECOG phase II trial of multi-epitope peptide vaccination for stage IV melanoma with MART-1 (27 … JM Kirkwood, S Lee, S Land, C Sander, R Mascari, LM Weiner, ... Journal of Clinical Oncology 22 (14_suppl), 7502-7502, 2004 | 19 | 2004 |