Wim Vanden Berghe
Wim Vanden Berghe
Professor Epigenetic Signaling, University Antwerp & University Gent
Verified email at - Homepage
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Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1
P Delerive, K De Bosscher, S Besnard, WV Berghe, JM Peters, ...
Journal of Biological Chemistry 274 (45), 32048-32054, 1999
The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: molecular mechanisms for gene repression
K De Bosscher, W Vanden Berghe, G Haegeman
Endocrine reviews 24 (4), 488-522, 2003
Transcriptional activation of the NF-κB p65 subunit by mitogen-and stress-activated protein kinase-1 (MSK1)
L Vermeulen, G De Wilde, P Van Damme, WV Berghe, G Haegeman
The EMBO journal 22 (6), 1313-1324, 2003
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor
WV Berghe, S Plaisance, E Boone, K De Bosscher, ML Schmitz, W Fiers, ...
Journal of Biological Chemistry 273 (6), 3285-3290, 1998
The p38/RK mitogen‐activated protein kinase pathway regulates interleukin‐6 synthesis response to tumor necrosis factor.
R Beyaert, A Cuenda, W Vanden Berghe, S Plaisance, JC Lee, ...
The EMBO journal 15 (8), 1914-1923, 1996
Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation
K De Bosscher, ML Schmitz, W Vanden Berghe, S Plaisance, W Fiers, ...
Proceedings of the National Academy of Sciences 94 (25), 13504-13509, 1997
The nuclear factor-κB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
WV Berghe, K De Bosscher, E Boone, S Plaisance, G Haegeman
Journal of Biological Chemistry 274 (45), 32091-32098, 1999
Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell
K De Bosscher, W Vanden Berghe, L Vermeulen, S Plaisance, E Boone, ...
Proceedings of the National Academy of Sciences 97 (8), 3919-3924, 2000
How glucocorticoid receptors modulate the activity of other transcription factors: a scope beyond tethering
D Ratman, WV Berghe, L Dejager, C Libert, J Tavernier, IM Beck, ...
Molecular and cellular endocrinology 380 (1-2), 41-54, 2013
Regulation of the transcriptional activity of the nuclear factor-κB p65 subunit
L Vermeulen, G De Wilde, S Notebaert, WV Berghe, G Haegeman
Biochemical pharmacology 64 (5-6), 963-970, 2002
Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6
WV Berghe, L Vermeulen, G De Wilde, K De Bosscher, E Boone, ...
Biochemical pharmacology 60 (8), 1185-1195, 2000
Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors
K De Bosscher, WV Berghe, G Haegeman
Journal of neuroimmunology 109 (1), 16-22, 2000
The zinc finger protein A20 inhibits TNF-induced NF-κB–dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal and directly binds to a …
K Heyninck, D De Valck, WV Berghe, W Van Criekinge, R Contreras, ...
The Journal of cell biology 145 (7), 1471-1482, 1999
Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases
IME Beck, W Vanden Berghe, L Vermeulen, KR Yamamoto, G Haegeman, ...
Endocrine reviews 30 (7), 830-882, 2009
Cross-talk between nuclear receptors and nuclear factor κB
K De Bosscher, W Vanden Berghe, G Haegeman
Oncogene 25 (51), 6868-6886, 2006
Withaferin A strongly elicits IκB kinase β hyperphosphorylation concomitant with potent inhibition of its kinase activity
M Kaileh, WV Berghe, A Heyerick, J Horion, J Piette, C Libert, ...
Journal of Biological Chemistry 282 (7), 4253-4264, 2007
A fully dissociated compound of plant origin for inflammatory gene repression
K De Bosscher, WV Berghe, IME Beck, W Van Molle, N Hennuyer, ...
Proceedings of the National Academy of Sciences 102 (44), 15827-15832, 2005
A paradigm for gene regulation: inflammation, NF-κB and PPAR
WV Berghe, L Vermeulen, P Delerive, KD Bosscher, B Staels, ...
Peroxisomal disorders and regulation of genes, 181-196, 2003
N-acetyl-l-cysteine inhibits primary human T cell responses at the dendritic cell level: association with NF-κB inhibition
V Verhasselt, WV Berghe, N Vanderheyde, F Willems, G Haegeman, ...
The Journal of immunology 162 (5), 2569-2574, 1999
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
B Hassannia, B Wiernicki, I Ingold, K Declerck, CS Chirumamilla, ...
The journal of clinical investigation., 1-16, 2018
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