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Rikke Nielsen
Rikke Nielsen
Verified email at biomed.au.dk
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Megalin and cubilin in proximal tubule protein reabsorption: from experimental models to human disease
R Nielsen, EI Christensen, H Birn
Kidney international 89 (1), 58-67, 2016
4292016
Attenuation of c GAS‐STING signaling is mediated by a p62/SQSTM 1‐dependent autophagy pathway activated by TBK1
T Prabakaran, C Bodda, C Krapp, B Zhang, MH Christensen, C Sun, ...
The EMBO journal 37 (8), e97858, 2018
3362018
Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules
EI Christensen, O Devuyst, G Dom, R Nielsen, P Van Der Smissen, ...
Proceedings of the National Academy of Sciences 100 (14), 8472-8477, 2003
3352003
Cubilin is essential for albumin reabsorption in the renal proximal tubule
S Amsellem, J Gburek, G Hamard, R Nielsen, TE Willnow, O Devuyst, ...
Journal of the American Society of Nephrology 21 (11), 1859-1867, 2010
3312010
Endocytic receptors in the renal proximal tubule
EI Christensen, H Birn, T Storm, K Weyer, R Nielsen
Physiology 27 (4), 223-236, 2012
3082012
Receptor-mediated endocytosis in renal proximal tubule
EI Christensen, PJ Verroust, R Nielsen
Pflügers Archiv-European Journal of Physiology 458, 1039-1048, 2009
2822009
Listeria monocytogenes induces IFNβ expression through an IFI16‐, cGAS‐ and STING‐dependent pathway
K Hansen, T Prabakaran, A Laustsen, SE Jørgensen, SH Rahbæk, ...
The EMBO journal 33 (15), 1654-1666, 2014
2642014
Cubilin-and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney
XY Zhai, R Nielsen, H Birn, K Drumm, S Mildenberger, R Freudinger, ...
Kidney international 58 (4), 1523-1533, 2000
2582000
The tandem endocytic receptors megalin and cubilin are important proteins in renal pathology
PJ Verroust, H Birn, R Nielsen, R Kozyraki, EI Christensen
Kidney international 62 (3), 745-756, 2002
1852002
Transforming growth factor‐β1 reduces megalin‐ and cubilin‐mediated endocytosis of albumin in proximal‐tubule‐derived opossum kidney cells
M Gekle, P Knaus, R Nielsen, S Mildenberger, R Freudinger, V Wohlfarth, ...
The Journal of physiology 552 (2), 471-481, 2003
1462003
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease
T Prabakaran, R Nielsen, JV Larsen, SS Sørensen, UF Rasmussen, ...
PloS one 6 (9), e25065, 2011
1312011
Proteinuria and events beyond the slit
R Nielsen, EI Christensen
Pediatric nephrology 25, 813-822, 2010
1262010
Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells
R Nielsen, PJ Courtoy, C Jacobsen, G Dom, WR Lima, M Jadot, ...
Proceedings of the National Academy of Sciences 104 (13), 5407-5412, 2007
1162007
Megalin antagonizes activation of the parathyroid hormone receptor
J Hilpert, A Nykjaer, C Jacobsen, G Wallukat, R Nielsen, SK Moestrup, ...
Journal of Biological Chemistry 274 (9), 5620-5625, 1999
1151999
Mutually dependent localization of megalin and Dab2 in the renal proximal tubule
J Nagai, EI Christensen, SM Morris, TE Willnow, JA Cooper, R Nielsen
American Journal of Physiology-Renal Physiology 289 (3), F569-F576, 2005
1102005
Megalin is essential for renal proximal tubule reabsorption and accumulation of transcobalamin-B12
H Birn, TE Willnow, R Nielsen, AGW Norden, C Bönsch, SK Moestrup, ...
American Journal of Physiology-Renal Physiology 282 (3), F408-F416, 2002
1042002
Megalin-mediated specific uptake of chitosan/siRNA nanoparticles in mouse kidney proximal tubule epithelial cells enables AQP1 gene silencing
S Gao, S Hein, F Dagnæs-Hansen, K Weyer, C Yang, R Nielsen, ...
Theranostics 4 (10), 1039, 2014
1032014
Characterization of a kidney proximal tubule cell line, LLC-PK1, expressing endocytotic active megalin.
R Nielsen, H Birn, SK Moestrup, M Nielsen, P Verroust, EI Christensen
Journal of the American Society of Nephrology 9 (10), 1767-1776, 1998
1011998
Renal phenotypic investigations of megalin-deficient patients: novel insights into tubular proteinuria and albumin filtration
T Storm, L Tranebjærg, C Frykholm, H Birn, PJ Verroust, T Nevéus, ...
Nephrology Dialysis Transplantation 28 (3), 585-591, 2013
872013
Renal uptake of 99mTc-dimercaptosuccinic acid is dependent on normal proximal tubule receptor–mediated endocytosis
K Weyer, R Nielsen, SV Petersen, EI Christensen, M Rehling, H Birn
Journal of Nuclear Medicine 54 (1), 159-165, 2013
842013
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