| PARP inhibitors: clinical relevance, mechanisms of action and tumor resistance M Rose, JT Burgess, K O’Byrne, DJ Richard, E Bolderson Frontiers in cell and developmental biology 8, 564601, 2020 | 415 | 2020 |
| Single-stranded DNA-binding protein hSSB1 is critical for genomic stability DJ Richard, E Bolderson, L Cubeddu, RIM Wadsworth, K Savage, ... Nature 453 (7195), 677-681, 2008 | 280 | 2008 |
| Nucleophosmin: from structure and function to disease development JK Box, N Paquet, MN Adams, D Boucher, E Bolderson, KJ O’Byrne, ... BMC molecular biology 17, 1-12, 2016 | 258 | 2016 |
| Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair E Bolderson, DJ Richard, BBS Zhou, KK Khanna Clinical Cancer Research 15 (20), 6314-6320, 2009 | 250 | 2009 |
| Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks E Bolderson, N Tomimatsu, DJ Richard, D Boucher, R Kumar, TK Pandita, ... Nucleic acids research 38 (6), 1821-1831, 2010 | 224 | 2010 |
| Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions N Tomimatsu, B Mukherjee, K Deland, A Kurimasa, E Bolderson, ... DNA repair 11 (4), 441-448, 2012 | 157 | 2012 |
| Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising C Jekimovs, E Bolderson, A Suraweera, M Adams, KJ O’Byrne, ... Frontiers in oncology 4, 86, 2014 | 135 | 2014 |
| HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response Y Li, E Bolderson, R Kumar, PA Muniandy, Y Xue, DJ Richard, ... Journal of biological chemistry 284 (35), 23525-23531, 2009 | 128 | 2009 |
| Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis DJ Richard, E Bolderson, KK Khanna Critical reviews in biochemistry and molecular biology 44 (2-3), 98-116, 2009 | 121 | 2009 |
| Human single-stranded DNA binding proteins are essential for maintaining genomic stability NW Ashton, E Bolderson, L Cubeddu, KJ O’Byrne, DJ Richard BMC molecular biology 14, 1-20, 2013 | 115 | 2013 |
| ATM is required for the cellular response to thymidine induced replication fork stress E Bolderson, J Scorah, T Helleday, C Smythe, M Meuth Human molecular genetics 13 (23), 2937-2945, 2004 | 106 | 2004 |
| Rad51 supports triple negative breast cancer metastasis AP Wiegmans, F Al-Ejeh, N Chee, PY Yap, JJ Gorski, L Da Silva, ... Oncotarget 5 (10), 3261, 2014 | 105 | 2014 |
| INTS3 controls the hSSB1-mediated DNA damage response JR Skaar, DJ Richard, A Saraf, A Toschi, E Bolderson, L Florens, ... Journal of cell biology 187 (1), 25-32, 2009 | 103 | 2009 |
| hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex DJ Richard, K Savage, E Bolderson, L Cubeddu, S So, M Ghita, DJ Chen, ... Nucleic acids research 39 (5), 1692-1702, 2011 | 98 | 2011 |
| hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity DJ Richard, L Cubeddu, AJ Urquhart, A Bain, E Bolderson, D Menon, ... Nucleic acids research 39 (9), 3643-3651, 2011 | 96 | 2011 |
| ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1 AW Kijas, YC Lim, E Bolderson, K Cerosaletti, M Gatei, B Jakob, F Tobias, ... Nucleic acids research 43 (17), 8352-8367, 2015 | 73 | 2015 |
| Multifocal urothelial cancers with the mutator phenotype are of monoclonal origin and require panurothelial treatment for tumor clearance JWF Catto, A Hartmann, R Stoehr, E Bolderson, I Rehman, DJ Rosario, ... The Journal of urology 175 (6), 2323-2330, 2006 | 68 | 2006 |
| Krüppel-associated box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1β (HP1-β) mobilization and DNA repair in heterochromatin E Bolderson, KI Savage, R Mahen, V Pisupati, ME Graham, DJ Richard, ... Journal of Biological Chemistry 287 (33), 28122-28131, 2012 | 67 | 2012 |
| Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks E Bolderson, E Petermann, L Croft, A Suraweera, RK Pandita, TK Pandita, ... Nucleic acids research 42 (10), 6326-6336, 2014 | 60 | 2014 |
| Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation N Paquet, JK Box, NW Ashton, A Suraweera, LV Croft, AJ Urquhart, ... BMC molecular biology 15, 1-11, 2014 | 52 | 2014 |
