Marc Ostermeier
Marc Ostermeier
Professor of Chemical and Biomolecular Engineering, Johns Hopkins University
Verified email at - Homepage
Cited by
Cited by
A combinatorial approach to hybrid enzymes independent of DNA homology
M Ostermeier, JH Shim, SJ Benkovic
Nature biotechnology 17 (12), 1205-1209, 1999
A comprehensive, high-resolution map of a gene’s fitness landscape
E Firnberg, JW Labonte, JJ Gray, M Ostermeier
Molecular biology and evolution 31 (6), 1581-1592, 2014
Directed evolution of protein switches and their application to the creation of ligand-binding proteins
G Guntas, TJ Mansell, JR Kim, M Ostermeier
Proceedings of the National Academy of Sciences 102 (32), 11224-11229, 2005
Creating multiple-crossover DNA libraries independent of sequence identity
S Lutz, M Ostermeier, GL Moore, CD Maranas, SJ Benkovic
Proceedings of the National Academy of Sciences 98 (20), 11248-11253, 2001
Combinatorial protein engineering by incremental truncation
M Ostermeier, AE Nixon, JH Shim, SJ Benkovic
Proceedings of the National Academy of Sciences 96 (7), 3562-3567, 1999
An externally tunable bacterial band-pass filter
T Sohka, RA Heins, RM Phelan, JM Greisler, CA Townsend, M Ostermeier
Proceedings of the National Academy of Sciences 106 (25), 10135-10140, 2009
Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells
G Georgiou, M Ostermeier
US Patent 6,027,888, 2000
Creation of an allosteric enzyme by domain insertion
G Guntas, M Ostermeier
Journal of molecular biology 336 (1), 263-273, 2004
Engineering allosteric protein switches by domain insertion
M Ostermeier
Protein Engineering Design and Selection 18 (8), 359-364, 2005
Rapid generation of incremental truncation libraries for protein engineering using α-phosphothioate nucleotides
S Lutz, M Ostermeier, SJ Benkovic
Nucleic Acids Research 29 (4), e16-e16, 2001
A molecular switch created by in vitro recombination of nonhomologous genes
G Guntas, SF Mitchell, M Ostermeier
Chemistry & biology 11 (11), 1483-1487, 2004
PFunkel: efficient, expansive, user-defined mutagenesis
E Firnberg, M Ostermeier
PloS one 7 (12), e52031, 2012
Eukaryotic protein disulfide isomerase complements Escherichia coli dsbA mutants and increases the yield of a heterologous secreted protein with disulfide bonds
M Ostermeier, K De Sutter, G Georgiou
Journal of Biological Chemistry 271 (18), 10616-10622, 1996
Mathematical expressions useful in the construction, description and evaluation of protein libraries
AD Bosley, M Ostermeier
Biomolecular engineering 22 (1-3), 57-61, 2005
Incremental truncation as a strategy in the engineering of novel biocatalysts
M Ostermeier, AE Nixon, SJ Benkovic
Bioorganic & medicinal chemistry 7 (10), 2139-2144, 1999
Hybrid enzymes: manipulating enzyme design
AE Nixon, M Ostermeier, SJ Benkovic
Trends in biotechnology 16 (6), 258-264, 1998
Environmental changes bridge evolutionary valleys
B Steinberg, M Ostermeier
Science advances 2 (1), e1500921, 2016
Evolution of protein function by domain swapping
M Ostermeier, SJ Benkovic
Advances in protein chemistry 55, 29-77, 2001
Folding and aggregation of TEM β‐lactamase: Analogies with the formation of inclusion bodies in Escherichia coli
G Georgiou, P Valax, M Ostermeier, PM Horowitz
Protein Science 3 (11), 1953-1960, 1994
Targeted DNA methylation in human cells using engineered dCas9-methyltransferases
T Xiong, GE Meister, RE Workman, NC Kato, MJ Spellberg, F Turker, ...
Scientific reports 7 (1), 6732, 2017
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