Scavenger receptor class B type I–mediated protection against atherosclerosis in LDL receptor–negative mice involves its expression in bone marrow–derived cells SD Covey, M Krieger, W Wang, M Penman, BL Trigatti Arteriosclerosis, thrombosis, and vascular biology 23 (9), 1589-1594, 2003 | 272 | 2003 |
The pancreatic β cell is a key site for mediating the effects of leptin on glucose homeostasis SD Covey, RD Wideman, C McDonald, S Unniappan, F Huynh, A Asadi, ... Cell metabolism 4 (4), 291-302, 2006 | 243 | 2006 |
Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling HC Denroche, J Levi, RD Wideman, RM Sequeira, FK Huynh, SD Covey, ... Diabetes 60 (5), 1414-1423, 2011 | 133 | 2011 |
Tissue-specific effects of leptin on glucose and lipid metabolism S Pereira, DL Cline, MM Glavas, SD Covey, TJ Kieffer Endocrine reviews 42 (1), 1-28, 2021 | 122 | 2021 |
Hyperinsulinemia precedes insulin resistance in mice lacking pancreatic β-cell leptin signaling SL Gray, C Donald, A Jetha, SD Covey, TJ Kieffer Endocrinology 151 (9), 4178-4186, 2010 | 122 | 2010 |
Disruption of hepatic leptin signaling protects mice from age-and diet-related glucose intolerance FK Huynh, J Levi, HC Denroche, SL Gray, PJ Voshol, UH Neumann, ... Diabetes 59 (12), 3032-3040, 2010 | 89 | 2010 |
FGF21-mediated improvements in glucose clearance require uncoupling protein 1 MM Kwon, SM O’Dwyer, RK Baker, SD Covey, TJ Kieffer Cell reports 13 (8), 1521-1527, 2015 | 85 | 2015 |
A role for hepatic leptin signaling in lipid metabolism via altered very low density lipoprotein composition and liver lipase activity in mice FK Huynh, UH Neumann, Y Wang, B Rodrigues, TJ Kieffer, SD Covey Hepatology 57 (2), 543-554, 2013 | 78 | 2013 |
A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted α-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis … RD Wideman, SD Covey, GC Webb, DJ Drucker, TJ Kieffer Diabetes 56 (11), 2744-2752, 2007 | 75 | 2007 |
Scavenger receptor class B type I in high-density lipoprotein metabolism, atherosclerosis and heart disease: lessons from gene-targeted mice B Trigatti, S Covey, A Rizvi Biochemical Society Transactions 32 (1), 116-120, 2004 | 73 | 2004 |
Leptin resistance following over-expression of protein tyrosine phosphatase 1B in liver NT Lam, SD Covey, JT Lewis, S Oosman, T Webber, EC Hsu, AT Cheung, ... Journal of Molecular Endocrinology 36 (1), 163-174, 2006 | 64 | 2006 |
The deubiquitinase activity of the Salmonella pathogenicity island 2 effector, SseL, prevents accumulation of cellular lipid droplets ET Arena, SD Auweter, LCM Antunes, AW Vogl, J Han, JA Guttman, ... Infection and Immunity 79 (11), 4392-4400, 2011 | 58 | 2011 |
Leptin deficiency in rats results in hyperinsulinemia and impaired glucose homeostasis AM D'souza, A Asadi, JD Johnson, SD Covey, TJ Kieffer Endocrinology 155 (4), 1268-1279, 2014 | 35 | 2014 |
Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival UH Neumann, JSS Ho, M Mojibian, SD Covey, MJ Charron, TJ Kieffer Molecular metabolism 5 (8), 731-736, 2016 | 33 | 2016 |
Hepatic leptin signalling and subdiaphragmatic vagal efferents are not required for leptin-induced increases of plasma IGF binding protein-2 (IGFBP-2) in ob/ob mice J Levi, FK Huynh, HC Denroche, UH Neumann, MM Glavas, SD Covey, ... Diabetologia 55, 752-762, 2012 | 32 | 2012 |
Leptin induces fasting hypoglycaemia in a mouse model of diabetes through the depletion of glycerol HC Denroche, MM Kwon, WL Quong, UH Neumann, JE Kulpa, ... Diabetologia 58, 1100-1108, 2015 | 30 | 2015 |
Insulin knockout mice have extended survival but volatile blood glucose levels on leptin therapy UH Neumann, HC Denroche, M Mojibian, SD Covey, TJ Kieffer Endocrinology 157 (3), 1007-1012, 2016 | 29 | 2016 |
IGFBP2 Is Neither Sufficient nor Necessary for the Physiological Actions of Leptin on Glucose Homeostasis in Male ob/ob Mice UH Neumann, S Chen, YYC Tam, RK Baker, SD Covey, PR Cullis, ... Endocrinology 155 (3), 716-725, 2014 | 29 | 2014 |
Transplantation of PC1/3-Expressing α-cells improves glucose handling and cold tolerance in leptin-resistant mice RD Wideman, SL Gray, SD Covey, GC Webb, TJ Kieffer Molecular Therapy 17 (1), 191-198, 2009 | 26 | 2009 |
Cholesterol depletion inhibits fatty acid uptake without affecting CD36 or caveolin-1 distribution in adipocytes SD Covey, RH Brunet, SG Gandhi, N McFarlane, DR Boreham, ... Biochemical and biophysical research communications 355 (1), 67-71, 2007 | 25 | 2007 |