Iannis Aifantis
Iannis Aifantis
NYU Grossman School of Medicine
Verified email at - Homepage
Cited by
Cited by
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
K Moran-Crusio, L Reavie, A Shih, O Abdel-Wahab, D Ndiaye-Lobry, ...
Cancer cell 20 (1), 11-24, 2011
The bone marrow microenvironment at single-cell resolution
AN Tikhonova, I Dolgalev, H Hu, KK Sivaraj, E Hoxha, ...
Nature 569 (7755), 222-228, 2019
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
O Abdel-Wahab, M Adli, LM LaFave, J Gao, T Hricik, AH Shih, S Pandey, ...
Cancer cell 22 (2), 180-193, 2012
Restoration of TET2 function blocks aberrant self-renewal and leukemia progression
L Cimmino, I Dolgalev, Y Wang, A Yoshimi, GH Martin, J Wang, V Ng, ...
Cell 170 (6), 1079-1095. e20, 2017
SRSF2 mutations contribute to myelodysplasia by mutant-specific effects on exon recognition
E Kim, JO Ilagan, Y Liang, GM Daubner, SCW Lee, A Ramakrishnan, Y Li, ...
Cancer cell 27 (5), 617-630, 2015
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
P Ntziachristos, A Tsirigos, PV Vlierberghe, J Nedjic, T Trimarchi, ...
Nature medicine 18 (2), 298-302, 2012
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
BJ Thompson, S Buonamici, ML Sulis, T Palomero, T Vilimas, G Basso, ...
The Journal of experimental medicine 204 (8), 1825-1835, 2007
Molecular pathogenesis of T-cell leukaemia and lymphoma
I Aifantis, E Raetz, S Buonamici
Nature Reviews Immunology 8 (5), 380-390, 2008
γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
PJ Real, V Tosello, T Palomero, M Castillo, E Hernando, E De Stanchina, ...
Nature medicine 15 (1), 50-58, 2009
Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML
CD DiNardo, IS Tiong, A Quaglieri, S MacRaild, S Loghavi, FC Brown, ...
Blood, The Journal of the American Society of Hematology 135 (11), 791-803, 2020
Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia
T Trimarchi, E Bilal, P Ntziachristos, G Fabbri, R Dalla-Favera, A Tsirigos, ...
Cell 158 (3), 593-606, 2014
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma
X Bonilla, L Parmentier, B King, F Bezrukov, G Kaya, V Zoete, ...
Nature genetics 48 (4), 398-406, 2016
From fly wings to targeted cancer therapies: a centennial for notch signaling
P Ntziachristos, JS Lim, J Sage, I Aifantis
Cancer cell 25 (3), 318-334, 2014
Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think
C Lobry, P Oh, I Aifantis
Journal of Experimental Medicine 208 (10), 1931-1935, 2011
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia
A Klinakis, C Lobry, O Abdel-Wahab, P Oh, H Haeno, S Buonamici, ...
Nature 473 (7346), 230-233, 2011
Targeting the NF-κB signaling pathway in Notch1-induced T-cell leukemia
T Vilimas, J Mascarenhas, T Palomero, M Mandal, S Buonamici, F Meng, ...
Nature medicine 13 (1), 70-77, 2007
Requirement for cyclin D3 in lymphocyte development and T cell leukemias
E Sicinska, I Aifantis, L Le Cam, W Swat, C Borowski, Q Yu, AA Ferrando, ...
Cancer cell 4 (6), 451-461, 2003
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
P Ntziachristos, A Tsirigos, GG Welstead, T Trimarchi, S Bakogianni, L Xu, ...
Nature 514 (7523), 513-517, 2014
Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo
O Abdel-Wahab, J Gao, M Adli, A Dey, T Trimarchi, YR Chung, C Kuscu, ...
Journal of Experimental Medicine 210 (12), 2641-2659, 2013
The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability
B King, T Trimarchi, L Reavie, L Xu, J Mullenders, P Ntziachristos, ...
Cell 153 (7), 1552-1566, 2013
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