Sophie de Carné Trécesson

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Julian DownwardFrancis Crick InstituteVerified email at crick.ac.uk
Phil EastDeputy Head Bioinformatics & Biostatistics, The Francis Crick InstituteVerified email at crick.ac.uk
Philippe Paul JUINTeam 8 "Stress adaptation and tumor escape" CRCINA, UMR 1232 INSERM, Université de NantesVerified email at univ-nantes.fr
Snijders apThe Francis Crick InstituteVerified email at crick.ac.uk
Karin BarnouinUCB BioPharmaVerified email at ucb.com
Matthew A. CoelhoWellcome Sanger InstituteVerified email at sanger.ac.uk
Miriam Molina ArcasThe Francis Crick InstituteVerified email at crick.ac.uk
Kristopher A. SarosiekHarvard School of Public Health (Dana-Farber Cancer Institute; Harvard Medical School)Verified email at hsph.harvard.edu
Anthony LetaiProfessor of Medicine, Dana-Farber Cancer InstituteVerified email at dfci.harvard.edu
gautier fabieninsermVerified email at univ-nantes.fr
agnes bassevilleresearch biologist, Institut de Cancérologie de l'OuestVerified email at inserm.fr
Catherine GuetteVerified email at ico.unicancer.fr
Arnaud VigneronCancer Research Center of Lyon. UMR INSERM1052, CNRS5286, Université Claude Bernard Lyon1, CentreVerified email at lyon.unicancer.fr
Stephen TaitCancer Research UK Beatson Institute and University of GlasgowVerified email at glasgow.ac.uk
Florian BockDepartment of Radiotherapy, Maastricht UniversityVerified email at maastrichtuniversity.nl
vuillier celineATER Université de NantesVerified email at etu.univ-nantes.fr
Alain MorelProfesseur émérite de biochimie et biologie moléculaireVerified email at univ-angers.fr
Charles SwantonFrancis Crick InstituteVerified email at crick.ac.uk
Frédérique Souazéuniversity of Nantes, CRCI2NA, INSERM U1307Verified email at inserm.fr
mario camponeInstitut De cancérologie de l'OuestVerified email at ico.unicancer.fr

Sophie de Carné Trécesson

Other namesSophie de Carné, Sophie de Carne

Francis Crick Institute

Verified email at crick.ac.uk

cancer immunology cancer stem cells RAS immunotherapy lung adenocarcinoma


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Oncogenic RAS signaling promotes tumor immunoresistance by stabilizing PD-L1 mRNA MA Coelho, S de Carné Trécesson, S Rana, D Zecchin, C Moore, ... Immunity 47 (6), 1083-1099. e6, 2017	522	2017
The cdk5 kinase regulates the STAT3 transcription factor to prevent DNA damage upon topoisomerase I inhibition S Courapied, H Sellier, S de Carné Trécesson, A Vigneron, AC Bernard, ... Journal of Biological Chemistry 285 (35), 26765-26778, 2010	95	2010
Antibodies against endogenous retroviruses promote lung cancer immunotherapy KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ... Nature 616 (7957), 563-573, 2023	81	2023
Tight sequestration of BH3 proteins by BCL-xL at subcellular membranes contributes to apoptotic resistance J Pécot, L Maillet, J Le Pen, C Vuillier, S de Carné Trécesson, A Fétiveau, ... Cell reports 17 (12), 3347-3358, 2016	63	2016
Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells A Basseville, L Preisser, S de Carné Trécesson, M Boisdron-Celle, ... Molecular cancer 10, 1-12, 2011	61	2011
Escape from p21-mediated oncogene-induced senescence leads to cell dedifferentiation and dependence on anti-apoptotic Bcl-xL and MCL1 proteins S de Carné Trécesson, Y Guillemin, A Bélanger, AC Bernard, L Preisser, ... Journal of Biological Chemistry 286 (15), 12825-12838, 2011	55	2011
Genomic–transcriptomic evolution in lung cancer and metastasis C Martínez-Ruiz, JRM Black, C Puttick, MS Hill, J Demeulemeester, ... Nature 616 (7957), 543-552, 2023	45	2023
Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1 B Jonchère, A Vétillard, B Toutain, D Lam, AC Bernard, C Henry, ... Oncotarget 6 (1), 409, 2015	45	2015
BCL-X_L directly modulates RAS signalling to favour cancer cell stemness S Carné Trécesson, F Souazé, A Basseville, AC Bernard, J Pécot, ... Nature Communications 8 (1), 1123, 2017	42	2017
Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival F Braun, S de Carné Trécesson, J Bertin-Ciftci, P Juin Cell Cycle 12 (18), 2937-2947, 2013	42	2013
An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations J Boumelha, S de Carné Trécesson, EK Law, P Romero-Clavijo, ... Cancer research 82 (19), 3435-3448, 2022	37*	2022
Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin) A Breiman, MDL Robles, S de Carné Trécesson, K Echasserieau, ... Oncotarget 7 (12), 14064, 2016	24	2016
RAS oncogenic activity predicts response to chemotherapy and outcome in lung adenocarcinoma P East, GP Kelly, D Biswas, M Marani, DC Hancock, T Creasy, ... Nature communications 13 (1), 5632, 2022	17	2022
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance DR Caswell, P Gui, MK Mayekar, EK Law, O Pich, C Bailey, J Boumelha, ... Nature Genetics 56 (1), 60-73, 2024	9	2024
Combining RAS^G12C(ON) inhibitor with SHP2 inhibition sensitises immune excluded lung tumours to immune checkpoint blockade: a strategy for turning cold … P Anastasiou, C Moore, S Rana, A de Castro, M Tomaschko, J Boumelha, ... bioRxiv, 2024.01. 15.575765, 2024	1	2024
In vivo CRISPR screen identifies KRAS-induced COX-2 as a driver of immune evasion and immunotherapy resistance in lung cancer J Boumelha, A de Castro, N Bah, H Cha, S de Carné Trécesson, S Rana, ... bioRxiv, 2023.04. 13.536740, 2023	1	2023
Oncogène RAS et Cancer Colorectal: Étude de la Réponse au Stress Oncogénique et de l'Échappement à la Sénescence S de Carné Trécesson Université d'Angers, 2010	1	2010
RAS orchestrates an increase of interstitial adenosine in lung adenocarcinoma to promote immune evasion S de Carné Trécesson, J Boumhela, C Moore, D Caswell, ... European Journal of Cancer 138, S20-S21, 2020		2020

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