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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes DJ Klionsky, H Abeliovich, P Agostinis, DK Agrawal, G Aliev, DS Askew, ... Autophagy 4 (2), 151-175, 2008 | 2665 | 2008 |
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors SB Joseph, BA Laffitte, PH Patel, MA Watson, KE Matsukuma, R Walczak, ... Journal of Biological Chemistry 277 (13), 11019-11025, 2002 | 891 | 2002 |
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway WA Freed-Pastor, H Mizuno, X Zhao, A Langerød, SH Moon, ... Cell 148 (1-2), 244-258, 2012 | 832 | 2012 |
Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action TF Osborne Journal of Biological Chemistry 275 (42), 32379-32382, 2000 | 663 | 2000 |
HMG CoA reductase: a negatively regulated gene with unusual promoter and 5′ untranslated regions GA Reynolds, SK Basu, TF Osborne, DJ Chin, G Gil, MS Brown, ... Cell 38 (1), 275-285, 1984 | 567 | 1984 |
SREBPs: metabolic integrators in physiology and metabolism TI Jeon, TF Osborne Trends in Endocrinology & Metabolism 23 (2), 65-72, 2012 | 521 | 2012 |
Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity Y Kidani, H Elsaesser, MB Hock, L Vergnes, KJ Williams, JP Argus, ... Nature immunology 14 (5), 489-499, 2013 | 425 | 2013 |
Sterol Regulation of Fatty Acid Synthase Promoter: COORDINATE FEEDBACK REGULATION OF TWO MAJOR LIPID PATHWAYS (∗) MK Bennett, JM Lopez, HB Sanchez, TF Osborne Journal of Biological Chemistry 270 (43), 25578-25583, 1995 | 421 | 1995 |
Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter MM Magaña, TF Osborne Journal of Biological Chemistry 271 (51), 32689-32694, 1996 | 394 | 1996 |
A feed-forward loop amplifies nutritional regulation of PNPLA3 Y Huang, S He, JZ Li, YK Seo, TF Osborne, JC Cohen, HH Hobbs Proceedings of the National Academy of Sciences 107 (17), 7892-7897, 2010 | 390 | 2010 |
Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein TS Worgall, SL Sturley, T Seo, TF Osborne, RJ Deckelbaum Journal of Biological Chemistry 273 (40), 25537-25540, 1998 | 358 | 1998 |
Thyroid hormone regulation and cholesterol metabolism are connected through sterol regulatory element-binding protein-2 (SREBP-2) DJ Shin, TF Osborne Journal of Biological Chemistry 278 (36), 34114-34118, 2003 | 354 | 2003 |
Cooperation by Sterol Regulatory Element-binding Protein and Sp1 in Sterol Regulation of Low Density Lipoprotein Receptor Gene (∗) HB Sanchez, L Yieh, TF Osborne Journal of Biological Chemistry 270 (3), 1161-1169, 1995 | 353 | 1995 |
Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a SS Im, L Yousef, C Blaschitz, JZ Liu, RA Edwards, SG Young, M Raffatellu, ... Cell metabolism 13 (5), 540-549, 2011 | 336 | 2011 |
Identification of nucleotides responsible for enhancer activity of sterol regulatory element in low density lipoprotein receptor gene. JR Smith, TF Osborne, JL Goldstein, MS Brown Journal of Biological Chemistry 265 (4), 2306-2310, 1990 | 301 | 1990 |
A Direct Role for Sterol Regulatory Element Binding Protein in Activation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Gene (∗) SM Vallett, HB Sanchez, JM Rosenfeld, TF Osborne Journal of Biological Chemistry 271 (21), 12247-12253, 1996 | 277 | 1996 |
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis M Blanc, WY Hsieh, KA Robertson, S Watterson, G Shui, P Lacaze, ... PLoS biology 9 (3), e1000598, 2011 | 274 | 2011 |
Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism S Masri, P Rigor, M Cervantes, N Ceglia, C Sebastian, C Xiao, ... Cell 158 (3), 659-672, 2014 | 265 | 2014 |
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been TF Osborne, PJ Espenshade Genes & development 23 (22), 2578-2591, 2009 | 258 | 2009 |