Hyperpolarized 13C MRI: path to clinical translation in oncology J Kurhanewicz, DB Vigneron, JH Ardenkjaer-Larsen, JA Bankson, ... Neoplasia 21 (1), 1-16, 2019 | 432 | 2019 |
Chemistry and biochemistry of 13 C hyperpolarized magnetic resonance using dynamic nuclear polarization KR Keshari, DM Wilson Chemical Society Reviews 43 (5), 1627-1659, 2014 | 388 | 2014 |
Quantitative analysis of prostate metabolites using 1H HR‐MAS spectroscopy MG Swanson, AS Zektzer, ZL Tabatabai, J Simko, S Jarso, KR Keshari, ... Magnetic Resonance in Medicine: An Official Journal of the International …, 2006 | 296 | 2006 |
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin L Chen, Y Shu, X Liang, EC Chen, SW Yee, AA Zur, S Li, L Xu, ... Proceedings of the National Academy of Sciences 111 (27), 9983-9988, 2014 | 240 | 2014 |
Metabolic Imaging of the Human Brain with Hyperpolarized 13C Pyruvate Demonstrates 13C Lactate Production in Brain Tumor Patients VZ Miloushev, KL Granlund, R Boltyanskiy, SK Lyashchenko, ... Cancer research 78 (14), 3755-3760, 2018 | 238 | 2018 |
Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using 1H HR‐MAS spectroscopy of biopsy tissues MB Tessem, MG Swanson, KR Keshari, MJ Albers, D Joun, ZL Tabatabai, ... Magnetic resonance in medicine 60 (3), 510-516, 2008 | 232 | 2008 |
Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo DM Wilson, KR Keshari, PEZ Larson, AP Chen, S Hu, M Van Criekinge, ... Journal of magnetic resonance 205 (1), 141-147, 2010 | 209 | 2010 |
Limited environmental serine and glycine confer brain metastasis sensitivity to PHGDH inhibition B Ngo, E Kim, V Osorio-Vasquez, S Doll, S Bustraan, RJ Liang, A Luengo, ... Cancer discovery 10 (9), 1352-1373, 2020 | 187 | 2020 |
Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging KR Keshari, J Kurhanewicz, R Bok, PEZ Larson, DB Vigneron, DM Wilson Proceedings of the National Academy of Sciences 108 (46), 18606-18611, 2011 | 181 | 2011 |
Lactic acid and proteoglycans as metabolic markers for discogenic back pain KR Keshari, JC Lotz, TM Link, S Hu, S Majumdar, J Kurhanewicz Spine 33 (3), 312-317, 2008 | 144 | 2008 |
Quantification of choline‐ and ethanolamine‐containing metabolites in human prostate tissues using 1H HR‐MAS total correlation spectroscopy MG Swanson, KR Keshari, ZL Tabatabai, JP Simko, K Shinohara, ... Magnetic Resonance in Medicine: An Official Journal of the International …, 2008 | 140 | 2008 |
Hyperpolarized [2-13C]-Fructose: A Hemiketal DNP Substrate for In Vivo Metabolic Imaging KR Keshari, DM Wilson, AP Chen, R Bok, PEZ Larson, S Hu, ... Journal of the American Chemical Society 131 (48), 17591-17596, 2009 | 134 | 2009 |
Imaging of blood flow using hyperpolarized [13C]Urea in preclinical cancer models C Von Morze, PEZ Larson, S Hu, K Keshari, DM Wilson, ... Journal of Magnetic Resonance Imaging 33 (3), 692-697, 2011 | 133 | 2011 |
Metabolic Reprogramming and Validation of Hyperpolarized 13C Lactate as a Prostate Cancer Biomarker Using a Human Prostate Tissue Slice Culture Bioreactor KR Keshari, R Sriram, M Van Criekinge, DM Wilson, ZJ Wang, ... The Prostate 73 (11), 1171-1181, 2013 | 132 | 2013 |
Hyperpolarized 13C-Pyruvate Magnetic Resonance Reveals Rapid Lactate Export in Metastatic Renal Cell Carcinomas KR Keshari, R Sriram, BL Koelsch, M Van Criekinge, DM Wilson, ... Cancer research 73 (2), 529-538, 2013 | 131 | 2013 |
Hyperpolarized MRI of human prostate cancer reveals increased lactate with tumor grade driven by monocarboxylate transporter 1 KL Granlund, SS Tee, HA Vargas, SK Lyashchenko, E Reznik, S Fine, ... Cell metabolism 31 (1), 105-114. e3, 2020 | 129 | 2020 |
A Boronate-Caged [18F]FLT Probe for Hydrogen Peroxide Detection Using Positron Emission Tomography V Carroll, BW Michel, J Blecha, H VanBrocklin, K Keshari, D Wilson, ... Journal of the American Chemical Society 136 (42), 14742-14745, 2014 | 127 | 2014 |
A Hydrogen Peroxide-Responsive Hyperpolarized 13C MRI Contrast Agent AR Lippert, KR Keshari, J Kurhanewicz, CJ Chang Journal of the American Chemical Society 133 (11), 3776-3779, 2011 | 116 | 2011 |
In vivo imaging of glutamine metabolism to the oncometabolite 2-hydroxyglutarate in IDH1/2 mutant tumors L Salamanca-Cardona, H Shah, AJ Poot, FM Correa, V Di Gialleonardo, ... Cell metabolism 26 (6), 830-841. e3, 2017 | 100 | 2017 |
Hyperpolarized 13C spectroscopy and an NMR‐compatible bioreactor system for the investigation of real‐time cellular metabolism KR Keshari, J Kurhanewicz, RE Jeffries, DM Wilson, BJ Dewar, ... Magnetic Resonance in Medicine: An Official Journal of the International …, 2010 | 93 | 2010 |