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Joseph A Toonen
Joseph A Toonen
Verified email at northwestern.edu
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Year
NF1 mutation drives neuronal activity-dependent initiation of optic glioma
Y Pan, JD Hysinger, T Barron, NF Schindler, O Cobb, X Guo, B Yalçın, ...
Nature 594 (7862), 277-282, 2021
1022021
RNA sequencing of tumor-associated microglia reveals Ccl5 as a stromal chemokine critical for neurofibromatosis-1 glioma growth
AC Solga, WW Pong, KY Kim, PJ Cimino, JA Toonen, J Walker, T Wylie, ...
Neoplasia 17 (10), 776-788, 2015
942015
Akt- or MEK-mediated mTOR inhibition suppresses Nf1 optic glioma growth
A Kaul, JA Toonen, PJ Cimino, SM Gianino, DH Gutmann
Neuro-oncology 17 (6), 843-853, 2015
892015
NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1
JA Toonen, C Anastasaki, LJ Smithson, SM Gianino, K Li, RA Kesterson, ...
Human molecular genetics 25 (9), 1703-1713, 2016
762016
Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma–induced retinal pathology
JA Toonen, AC Solga, Y Ma, DH Gutmann
Journal of Experimental Medicine 214 (1), 17-25, 2017
622017
Defining the temporal course of murine neurofibromatosis-1 optic gliomagenesis reveals a therapeutic window to attenuate retinal dysfunction
JA Toonen, Y Ma, DH Gutmann
Neuro-oncology 19 (6), 808-819, 2017
422017
The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation
AC Solga, JA Toonen, Y Pan, PJ Cimino, Y Ma, GA Castillon, SM Gianino, ...
Oncotarget 8 (29), 47206, 2017
302017
Waved with open eyelids 2 (woe2) is a novel spontaneous mouse mutation in the protein phosphatase 1, regulatory (inhibitor) subunit 13 like (Ppp1r13l)gene
J Toonen, L Liang, DJ Sidjanin
BMC genetics 13, 1-10, 2012
262012
Increased tissue stiffness in tumors from mice with neurofibromatosis-1 optic glioma
C Walter, L Crawford, M Lai, JA Toonen, Y Pan, S Sakiyama-Elbert, ...
Biophysical journal 112 (8), 1535-1538, 2017
242017
The impact of coexisting genetic mutations on murine optic glioma biology
A Kaul, JA Toonen, SM Gianino, DH Gutmann
Neuro-oncology 17 (5), 670-677, 2015
222015
ADAM17 transactivates EGFR signaling during embryonic eyelid closure
EL Hassemer, B Endres, JA Toonen, A Ronchetti, R Dubielzig, ...
Investigative ophthalmology & visual science 54 (1), 132-140, 2013
222013
Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature
Y Pan, EC Bush, JA Toonen, Y Ma, AC Solga, PA Sims, DH Gutmann
Oncotarget 8 (32), 52474, 2017
212017
A Disintegrin and metalloproteinase10 (ADAM10) regulates NOTCH signaling during early retinal development
JA Toonen, A Ronchetti, DJ Sidjanin
PLoS One 11 (5), e0156184, 2016
212016
Contextual signaling in cancer
LJ Smithson, C Anastasaki, R Chen, JA Toonen, SB Williams, ...
Seminars in cell & developmental biology 58, 118-126, 2016
102016
Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature. Oncotarget. 2017; 8: 52474–87
Y Pan, EC Bush, JA Toonen, Y Ma, AC Solga, PA Sims, DH Gutmann, ...
Impact Journals, 0
5
The role of ADAM10 in retinal development
J Toonen, D Sidjanin
Investigative Ophthalmology & Visual Science 54 (15), 5151-5151, 2013
22013
TAMI-69. NF1 MUTATION DRIVES NEURONAL ACTIVITY-DEPENDENT OPTIC GLIOMA INITIATION
Y Pan, J Hysinger, T Barron, N Schindler, O Cobb, X Guo, B Yalçın, ...
Neuro-Oncology 23 (Suppl 6), vi212, 2021
12021
LGG-01. NF1 MUTATION DRIVES NEURONAL ACTIVITY-DEPENDENT OPTIC GLIOMA INITIATION
Y Pan, J Hysinger, N Schindler, O Cobb, X Guo, B Yalçın, C Anastasaki, ...
Neuro-Oncology 23 (Suppl 1), i31, 2021
2021
Abstract P1-08-01: Regulation of estrogen receptor-α by NF1
ZY Zheng, B Cakar, P Lavere, J Cao, J Yao, P Singh, JT Lei, JA Toonen, ...
Cancer Research 77 (4_Supplement), P1-08-01-P1-08-01, 2017
2017
Adisintegrin and metalloproteinase 10 (ADAM10) is a regulator of lens development
DJ Sidjanin, J Toonen
Investigative Ophthalmology & Visual Science 56 (7), 4007-4007, 2015
2015
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