Cheril Tapia Rojas
Cheril Tapia Rojas
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Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics
A Carreras-Sureda, F Jaña, H Urra, S Durand, DE Mortenson, A Sagredo, ...
Nature cell biology 21 (6), 755-767, 2019
Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of A lzheimer's Disease
C Tapia‐Rojas, F Aranguiz, L Varela‐Nallar, NC Inestrosa
Brain Pathology 26 (1), 62-74, 2016
It’s all about tau
C Tapia-Rojas, F Cabezas-Opazo, CA Deaton, EH Vergara, ...
Progress in neurobiology 175, 54-76, 2019
Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer’s disease
ÁO Ardiles, CC Tapia-Rojas, M Mandal, F Alexandre, A Kirkwood, ...
Proceedings of the National Academy of Sciences 109 (34), 13835-13840, 2012
Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents
E Viayna, I Sola, M Bartolini, A De Simone, C Tapia-Rojas, FG Serrano, ...
Journal of medicinal chemistry 57 (6), 2549-2567, 2014
Loss of canonical Wnt signaling is involved in the pathogenesis of Alzheimer's disease
C Tapia-Rojas, NC Inestrosa
Neural regeneration research 13 (10), 1705, 2018
Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice
FG Serrano, C Tapia-Rojas, FJ Carvajal, J Hancke, W Cerpa, ...
Molecular neurodegeneration 9 (1), 61, 2014
Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral …
C Tapia-Rojas, CB Lindsay, C Montecinos-Oliva, MS Arrazola, ...
Molecular neurodegeneration 10 (1), 62, 2015
Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3β: autoregulation of GSK-3β in vivo
C Tapia-Rojas, A Schüller, CB Lindsay, RC Ureta, C Mejías-Reyes, ...
Biochemical Journal 466 (2), 415-430, 2015
Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20‐APP transgenic and wild‐type mice
C Tapia‐Rojas, NC Inestrosa
Journal of neurochemistry 144 (4), 443-465, 2018
Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid‐β (Aβ)42 peptides
C Tapia‐Rojas, PV Burgos, NC Inestrosa
Journal of neurochemistry 139 (6), 1175-1191, 2016
Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus
C Jara, A Aránguiz, W Cerpa, C Tapia-Rojas, RA Quintanilla
Redox biology 18, 279-294, 2018
Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect …
NC Inestrosa, C Tapia-Rojas, TN Griffith, FJ Carvajal, MJ Benito, ...
Translational psychiatry 1 (7), e20-e20, 2011
Peroxisome proliferators reduce spatial memory impairment, synaptic failure, and neurodegeneration in brains of a double transgenic mice model of Alzheimer's disease
NC Inestrosa, FJ Carvajal, JM Zolezzi, C Tapia-Rojas, F Serrano, ...
Journal of Alzheimer's Disease 33 (4), 941-959, 2013
Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss
MA Olesen, AK Torres, C Jara, MP Murphy, C Tapia-Rojas
Redox Biology, 101558, 2020
Adolescent binge alcohol exposure affects the brain function through mitochondrial impairment
C Tapia-Rojas, FJ Carvajal, RG Mira, C Arce, JM Lerma-Cabrera, ...
Molecular neurobiology 55 (5), 4473-4491, 2018
Andrographolide stimulates neurogenesis in the adult hippocampus
L Varela-Nallar, SB Arredondo, C Tapia-Rojas, J Hancke, NC Inestrosa
Neural plasticity 2015, 2015
Alzheimer’s disease-related protein expression in the retina of Octodon degus
LY Du, LYL Chang, AO Ardiles, C Tapia-Rojas, J Araya, NC Inestrosa, ...
PLoS One 10 (8), 2015
Pathologically phosphorylated tau at S396/404 (PHF-1) is accumulated inside of hippocampal synaptic mitochondria of aged Wild-type mice
AK Torres, C Jara, MA Olesen, C Tapia-Rojas
Scientific Reports 11 (1), 1-17, 2021
Alcohol impairs hippocampal function: From NMDA receptor synaptic transmission to mitochondrial function
RG Mira, C Tapia-Rojas, MJ Pérez, C Jara, EH Vergara, RA Quintanilla, ...
Drug and Alcohol Dependence, 107628, 2019
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