Essential metabolism for a minimal cell M Breuer, TM Earnest, C Merryman, KS Wise, L Sun, MR Lynott, ... Elife 8, e36842, 2019 | 146 | 2019 |
Fundamental behaviors emerge from simulations of a living minimal cell ZR Thornburg, DM Bianchi, TA Brier, BR Gilbert, TM Earnest, MCR Melo, ... Cell 185 (2), 345-360. e28, 2022 | 96 | 2022 |
DNA looping increases the range of bistability in a stochastic model of the lac genetic switch TM Earnest, E Roberts, M Assaf, K Dahmen, Z Luthey-Schulten Physical biology 10 (2), 026002, 2013 | 51 | 2013 |
Simulating biological processes: stochastic physics from whole cells to colonies TM Earnest, JA Cole, Z Luthey-Schulten Reports on Progress in Physics 81 (5), 052601, 2018 | 37 | 2018 |
Toward a whole-cell model of ribosome biogenesis: kinetic modeling of SSU assembly TM Earnest, J Lai, K Chen, MJ Hallock, JR Williamson, Z Luthey-Schulten Biophysical journal 109 (6), 1117-1135, 2015 | 31 | 2015 |
Single-molecule packaging initiation in real time by a viral DNA packaging machine from bacteriophage T4 R Vafabakhsh, K Kondabagil, T Earnest, KS Lee, Z Zhang, L Dai, ... Proceedings of the National Academy of Sciences 111 (42), 15096-15101, 2014 | 27 | 2014 |
Challenges of integrating stochastic dynamics and cryo-electron tomograms in whole-cell simulations TM Earnest, R Watanabe, JE Stone, J Mahamid, W Baumeister, E Villa, ... The Journal of Physical Chemistry B 121 (15), 3871-3881, 2017 | 17 | 2017 |
Ribosome biogenesis in replicating cells: integration of experiment and theory TM Earnest, JA Cole, JR Peterson, MJ Hallock, TE Kuhlman, ... Biopolymers 105 (10), 735-751, 2016 | 17 | 2016 |
Hybrid CME–ODE method for efficient simulation of the galactose switch in yeast DM Bianchi, JR Peterson, TM Earnest, MJ Hallock, Z Luthey‐Schulten IET Systems Biology 12 (4), 170-176, 2018 | 9 | 2018 |
Highly accurate response prediction in high-risk early breast cancer patients using a biophysical simulation platform FM Howard, G He, JR Peterson, JR Pfeiffer, T Earnest, AT Pearson, H Abe, ... Breast Cancer Research and Treatment 196 (1), 57-66, 2022 | 5 | 2022 |
Reverse-chaperoning activity of an AAA+ protein C Liu, MC McKinney, YH Chen, TM Earnest, X Shi, LJ Lin, Y Ishino, ... Biophysical journal 100 (5), 1344-1352, 2011 | 5 | 2011 |
SimBioSys TumorScope: Spatio-temporal modeling of the tumor microenvironment to predict chemotherapeutic response. JA Cole, JR Peterson, TM Earnest, MJ Hallock, JR Pfeiffer, T Pandey, ... Journal of Clinical Oncology 38 (15_suppl), e12650-e12650, 2020 | 3 | 2020 |
Nonlinear Sigma Model CC Chen, T Earnest University of Illinois, 1995 | 2 | 1995 |
Abstract P1-08-31: Simbiosys tumorscope: Biophysical modeling of patient-specific response to chemotherapy JA Cole Jr, JR Peterson, TM Earnest, MJ Hallock, DJ Cook, E Braun, ... Cancer Research 82 (4_Supplement), P1-08-31-P1-08-31, 2022 | 1 | 2022 |
Need for systematic de-escalation of care in HER2+ breast cancer patients. T Pandey, TM Earnest, JA Cole, E Braun Journal of Clinical Oncology 38 (15_suppl), e12657-e12657, 2020 | 1 | 2020 |
Abstract P1-06-04: SimBioSys TumorScope: Spatio-temporal modeling of the breast tumor microenvironment accurately predicts chemotherapeutic response JA Cole Jr, JR Peterson, TM Earnest, MJ Hallock, E Braun Cancer Research 80 (4_Supplement), P1-06-04-P1-06-04, 2020 | 1 | 2020 |
Stochastic and physical modeling of fundamental biological processes TM Earnest University of Illinois at Urbana-Champaign, 2016 | 1 | 2016 |
Corrigendum: DNA looping increases the range of bistability in a stochastic model of the lac genetic switch (2013 Phys. Biol. 10 026002) TM Earnest, E Roberts, M Assaf, K Dahmen, Z Luthey-Schulten Physical Biology 11 (2), 029501, 2014 | 1 | 2014 |
Seeing beyond cancer: multi-institutional validation of object localization and 3D semantic segmentation using deep learning for breast MRI A Pekis, V Kannan, E Kaklamanos, A Antony, S Patel, T Earnest Medical Imaging 2024: Computer-Aided Diagnosis 12927, 91-99, 2024 | | 2024 |
Learning to target CDK4/6 inhibitor resistance via a breast cancer-specific atlas of cellular mechanisms A Yaari, E Farias, F Guedes, O Priebe, L McDaniel, T Earnest, T Ideker, ... Cancer Research 84 (6_Supplement), 3287-3287, 2024 | | 2024 |