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Douglas Tilley
Douglas Tilley
Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University
Verified email at temple.edu - Homepage
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Cited by
Cited by
Year
β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection
T Noma, A Lemaire, SVN Prasad, L Barki-Harrington, DG Tilley, J Chen, ...
The Journal of clinical investigation 117 (9), 2445-2458, 2007
5352007
Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system
DH Maurice, D Palmer, DG Tilley, HA Dunkerley, SJ Netherton, ...
Molecular pharmacology 64 (3), 533-546, 2003
4112003
β-Blockers alprenolol and carvedilol stimulate β-arrestin-mediated EGFR transactivation
IM Kim, DG Tilley, J Chen, NC Salazar, EJ Whalen, JD Violin, ...
Proceedings of the National Academy of Sciences 105 (38), 14555-14560, 2008
3132008
Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway
Y Yin, X Li, X Sha, H Xi, YF Li, Y Shao, J Mai, A Virtue, J Lopez-Pastrana, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (4), 804-816, 2015
1962015
G protein–dependent and G protein–independent signaling pathways and their impact on cardiac function
DG Tilley
Circulation research 109 (2), 217-230, 2011
1842011
β-Arrestin mediates β1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling
DG Tilley, IM Kim, PA Patel, JD Violin, HA Rockman
Journal of biological chemistry 284 (30), 20375-20386, 2009
1212009
β-arrestin–biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction
R Carr III, J Schilling, J Song, RL Carter, Y Du, SM Yoo, CJ Traynham, ...
Proceedings of the National Academy of Sciences 113 (28), E4107-E4116, 2016
1172016
BAG3: a new player in the heart failure paradigm
T Knezevic, VD Myers, J Gordon, DG Tilley, TE Sharp, JF Wang, K Khalili, ...
Heart failure reviews 20, 423-434, 2015
1062015
Expression of phosphodiesterase 4D (PDE4D) is regulated by both the cyclic AMP-dependent protein kinase and mitogen-activated protein kinase signaling pathways: a potential …
H Liu, D Palmer, SL Jimmo, DG Tilley, HA Dunkerley, SC Pang, ...
Journal of Biological Chemistry 275 (34), 26615-26624, 2000
1062000
Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II
T Takayanagi, T Kawai, SJ Forrester, T Obama, T Tsuji, Y Fukuda, ...
Hypertension 65 (6), 1349-1355, 2015
1022015
Role of β-adrenergic receptor signaling and desensitization in heart failure: new concepts and prospects for treatment
DG Tilley, HA Rockman
Expert review of cardiovascular therapy 4 (3), 417-432, 2006
1002006
Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy
AM Feldman, RL Begay, T Knezevic, VD Myers, DB Slavov, W Zhu, ...
Journal of cellular physiology 229 (11), 1697-1702, 2014
902014
GRK5-mediated exacerbation of pathological cardiac hypertrophy involves facilitation of nuclear NFAT activity
JE Hullmann, LA Grisanti, CA Makarewich, E Gao, JI Gold, JK Chuprun, ...
Circulation research 115 (12), 976-985, 2014
882014
BAG3 regulates contractility and Ca2+ homeostasis in adult mouse ventricular myocytes
AM Feldman, J Gordon, JF Wang, J Song, XQ Zhang, VD Myers, DG Tilley, ...
Journal of molecular and cellular cardiology 92, 10-20, 2016
762016
Nuclear translocation of cardiac G protein-coupled receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process
JI Gold, JS Martini, J Hullmann, E Gao, JK Chuprun, L Lee, DG Tilley, ...
PloS one 8 (3), e57324, 2013
762013
Interleukin-10 inhibits bone marrow fibroblast progenitor cell–mediated cardiac fibrosis in pressure-overloaded myocardium
SK Verma, VNS Garikipati, P Krishnamurthy, SM Schumacher, LA Grisanti, ...
Circulation 136 (10), 940-953, 2017
722017
Vascular smooth muscle cell phosphodiesterase (PDE) 3 and PDE4 activities and levels are regulated by cyclic AMP in vivo
DG Tilley, DH Maurice
Molecular pharmacology 62 (3), 497-506, 2002
692002
The role of leukocytes in diabetic cardiomyopathy
A Bajpai, DG Tilley
Frontiers in Physiology 9, 414651, 2018
682018
β-Adrenergic regulation of cardiac progenitor cell death versus survival and proliferation
M Khan, S Mohsin, D Avitabile, S Siddiqi, J Nguyen, K Wallach, P Quijada, ...
Circulation research 112 (3), 476-486, 2013
682013
Leukocyte-Expressed β2-Adrenergic Receptors Are Essential for Survival After Acute Myocardial Injury
LA Grisanti, AM Gumpert, CJ Traynham, JE Gorsky, AA Repas, E Gao, ...
Circulation 134 (2), 153-167, 2016
662016
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