| Dengue virus activates cGAS through the release of mitochondrial DNA B Sun, KB Sundström, JJ Chew, P Bist, ES Gan, HC Tan, KC Goh, ... Scientific reports 7 (1), 3594, 2017 | 211 | 2017 |
| Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development R De Alwis, S Chen, ES Gan, EE Ooi EBioMedicine 55, 2020 | 164 | 2020 |
| A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice R De Alwis, ES Gan, S Chen, YS Leong, HC Tan, SL Zhang, C Yau, ... Molecular Therapy 29 (6), 1970-1983, 2021 | 141 | 2021 |
| Cross-reactive antibodies enhance live attenuated virus infection for increased immunogenicity KR Chan, X Wang, WAA Saron, ES Gan, HC Tan, DZL Mok, SLX Zhang, ... Nature microbiology 1 (12), 1-10, 2016 | 90 | 2016 |
| Molecular determinants of plaque size as an indicator of dengue virus attenuation KCM Goh, CK Tang, DC Norton, ES Gan, HC Tan, B Sun, A Syenina, ... Scientific reports 6 (1), 26100, 2016 | 65 | 2016 |
| Dengue virus induces PCSK9 expression to alter antiviral responses and disease outcomes ES Gan, HC Tan, DHT Le, TT Huynh, B Wills, NG Seidah, EE Ooi, ... The Journal of Clinical Investigation 130 (10), 5223-5234, 2020 | 44 | 2020 |
| Metabolic perturbations and cellular stress underpin susceptibility to symptomatic live-attenuated yellow fever infection KR Chan, ES Gan, CYY Chan, C Liang, JZH Low, SLX Zhang, EZ Ong, ... Nature Medicine 25 (8), 1218-1224, 2019 | 39 | 2019 |
| A systematic approach to the development of a safe live attenuated Zika vaccine SS Kwek, S Watanabe, KR Chan, EZ Ong, HC Tan, WC Ng, MTX Nguyen, ... Nature communications 9 (1), 1031, 2018 | 39 | 2018 |
| The mechanistic role of antibodies to dengue virus in protection and disease pathogenesis ES Gan, DHR Ting, KR Chan Expert Review of Anti-Infective Therapy 15 (2), 111-119, 2017 | 37 | 2017 |
| Rational engineering and characterization of an mAb that neutralizes Zika virus by targeting a mutationally constrained quaternary epitope K Tharakaraman, S Watanabe, KR Chan, J Huan, V Subramanian, ... Cell host & microbe 23 (5), 618-627. e6, 2018 | 31 | 2018 |
| Dengue virus compartmentalization during antibody-enhanced infection EZ Ong, SL Zhang, HC Tan, ES Gan, KR Chan, EE Ooi Scientific Reports 7 (1), 40923, 2017 | 31 | 2017 |
| Adverse effects following anti–COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T … A Syenina, ES Gan, JZN Toh, R de Alwis, LZ Lin, CYL Tham, JX Yee, ... PLoS Biology 20 (5), e3001643, 2022 | 28 | 2022 |
| Identification and in vivo Efficacy Assessment of Approved Orally Bioavailable Human Host Protein-Targeting Drugs With Broad Anti-influenza A Activity T Enkirch, S Sauber, DE Anderson, ES Gan, D Kenanov, S Maurer-Stroh, ... Frontiers in immunology 10, 1097, 2019 | 26 | 2019 |
| Positive epistasis between viral polymerase and the 3′ untranslated region of its genome reveals the epidemiologic fitness of dengue virus A Syenina, D Vijaykrishna, ES Gan, HC Tan, MM Choy, ... Proceedings of the National Academy of Sciences 117 (20), 11038-11047, 2020 | 24 | 2020 |
| Antibody-Dependent dengue virus entry modulates cell intrinsic responses for enhanced infection CYY Chan, JZH Low, ES Gan, EZ Ong, SLX Zhang, HC Tan, X Chai, ... Msphere 4 (5), 10.1128/msphere. 00528-19, 2019 | 24 | 2019 |
| Hypoxia enhances antibody‐dependent dengue virus infection ES Gan, WF Cheong, KR Chan, EZ Ong, X Chai, HC Tan, S Ghosh, ... The EMBO Journal 36 (10), 1348-1363, 2017 | 23 | 2017 |
| Dysregulated metabolism underpins Zika-virus-infection-associated impairment in fetal development C Yau, JZH Low, ES Gan, SS Kwek, L Cui, HC Tan, DZL Mok, CYY Chan, ... Cell Reports 37 (11), 2021 | 22 | 2021 |
| Oxygen: viral friend or foe? ES Gan, EE Ooi Virology Journal 17 (1), 115, 2020 | 20 | 2020 |
| Hypoxia and viral infectious diseases R Huang, M Huestis, ES Gan, EE Ooi, M Ohh JCI insight 6 (7), 2021 | 18 | 2021 |
| A mouse model of lethal respiratory dysfunction for SARS-CoV-2 infection ES Gan, A Syenina, M Linster, B Ng, SL Zhang, S Watanabe, ... Antiviral Research 193, 105138, 2021 | 14 | 2021 |
Chan Kuan RongDuke-NUSVerified email at duke-nus.edu.sg
