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Omar O. Abudayyeh
Omar O. Abudayyeh
McGovern Fellow, MIT
Verified email at mit.edu - Homepage
Title
Cited by
Cited by
Year
Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system
B Zetsche, JS Gootenberg, OO Abudayyeh, IM Slaymaker, KS Makarova, ...
cell 163 (3), 759-771, 2015
46162015
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ...
Nature 517 (7536), 583-588, 2015
28572015
Nucleic acid detection with CRISPR-Cas13a/C2c2
JS Gootenberg, OO Abudayyeh, JW Lee, P Essletzbichler, AJ Dy, J Joung, ...
Science 356 (6336), 438-442, 2017
27032017
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
OO Abudayyeh, JS Gootenberg, S Konermann, J Joung, IM Slaymaker, ...
Science 353 (6299), aaf5573, 2016
20762016
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
JS Gootenberg, OO Abudayyeh, MJ Kellner, J Joung, JJ Collins, F Zhang
Science 360 (6387), 439-444, 2018
19132018
RNA targeting with CRISPR–Cas13
OO Abudayyeh, JS Gootenberg, P Essletzbichler, S Han, J Joung, ...
Nature 550 (7675), 280-284, 2017
17452017
RNA editing with CRISPR-Cas13
DBT Cox, JS Gootenberg, OO Abudayyeh, B Franklin, MJ Kellner, J Joung, ...
Science 358 (6366), 1019-1027, 2017
16872017
Discovery and functional characterization of diverse class 2 CRISPR-Cas systems
S Shmakov, OO Abudayyeh, KS Makarova, YI Wolf, JS Gootenberg, ...
Molecular cell 60 (3), 385-397, 2015
13072015
Field-deployable viral diagnostics using CRISPR-Cas13
C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh, HC Metsky, ...
Science 360 (6387), 444-448, 2018
11072018
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
J Joung, S Konermann, JS Gootenberg, OO Abudayyeh, RJ Platt, ...
Nature protocols 12 (4), 828-863, 2017
10712017
Diversity and evolution of class 2 CRISPR–Cas systems
S Shmakov, A Smargon, D Scott, D Cox, N Pyzocha, W Yan, ...
Nature reviews microbiology 15 (3), 169-182, 2017
10172017
SHERLOCK: nucleic acid detection with CRISPR nucleases
MJ Kellner, JG Koob, JS Gootenberg, OO Abudayyeh, F Zhang
Nature protocols 14 (10), 2986-3012, 2019
9802019
Engineered CRISPR-Cas9 nuclease with expanded targeting space
H Nishimasu, X Shi, S Ishiguro, L Gao, S Hirano, S Okazaki, T Noda, ...
Science 361 (6408), 1259-1262, 2018
9612018
Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array
B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ...
Nature biotechnology 35 (1), 31-34, 2017
9042017
Detection of SARS-CoV-2 with SHERLOCK one-pot testing
J Joung, A Ladha, M Saito, NG Kim, AE Woolley, M Segel, RPJ Barretto, ...
New England Journal of Medicine 383 (15), 1492-1494, 2020
5832020
Cas13b is a type VI-B CRISPR-associated RNA-guided RNase differentially regulated by accessory proteins Csx27 and Csx28
AA Smargon, DBT Cox, NK Pyzocha, K Zheng, IM Slaymaker, ...
Molecular cell 65 (4), 618-630. e7, 2017
5642017
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors
DJ Konieczkowski, CM Johannessen, O Abudayyeh, JW Kim, ZA Cooper, ...
Cancer discovery 4 (7), 816-827, 2014
5362014
CRISPR-based diagnostics
MM Kaminski, OO Abudayyeh, JS Gootenberg, F Zhang, JJ Collins
Nature Biomedical Engineering 5 (7), 643-656, 2021
5342021
Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA
M Patchsung, K Jantarug, A Pattama, K Aphicho, S Suraritdechachai, ...
Nature biomedical engineering 4 (12), 1140-1149, 2020
4842020
CRISPR enzymes and systems
F Zhang, B Zetsche, I Slaymaker, J Gootenberg, OO Abudayyeh
US Patent 9,790,490, 2017
4842017
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