Jaap Middeldorp
Jaap Middeldorp
professor @ VU University medical center and CEO @ Cyto-Barr BV
Verified email at vumc.nl - Homepage
Title
Cited by
Cited by
Year
Functional delivery of viral miRNAs via exosomes
DM Pegtel, K Cosmopoulos, DA Thorley-Lawson, MAJ van Eijndhoven, ...
Proceedings of the National Academy of Sciences 107 (14), 6328-6333, 2010
12642010
Exosomes: fit to deliver small RNA
A Zomer, T Vendrig, ES Hopmans, M van Eijndhoven, JM Middeldorp, ...
Communicative & integrative biology 3 (5), 447-450, 2010
3192010
Nontemplated nucleotide additions distinguish the small RNA composition in cells from exosomes
D Koppers-Lalic, M Hackenberg, IV Bijnsdorp, MAJ van Eijndhoven, ...
Cell reports 8 (6), 1649-1658, 2014
3122014
Frequent monitoring of Epstein-Barr virus DNA load in unfractionated whole blood is essential for early detection of posttransplant lymphoproliferative disease in high-risk …
SJC Stevens, EAM Verschuuren, I Pronk, W van der Bij, MC Harmsen, ...
Blood, The Journal of the American Society of Hematology 97 (5), 1165-1171, 2001
3112001
Demonstration of the Burkitt's lymphoma Epstein-Barr virus phenotype in dividing latently infected memory cells in vivo
D Hochberg, JM Middeldorp, M Catalina, JL Sullivan, K Luzuriaga, ...
Proceedings of the National Academy of Sciences 101 (1), 239-244, 2004
2902004
Unique transcription pattern of Epstein-Barr virus (EBV) in EBV-carrying gastric adenocarcinomas: expression of the transforming BARF1 gene
A zur Hausen, AATP Brink, ME Craanen, JM Middeldorp, CJLM Meijer, ...
Cancer Research 60 (10), 2745-2748, 2000
2592000
Nasopharyngeal carcinoma in Indonesia: epidemiology, incidence, signs, and symptoms at presentation
M Adham, AN Kurniawan, AI Muhtadi, A Roezin, B Hermani, ...
Chinese journal of cancer 31 (4), 185, 2012
2502012
Differential immunogenicity of Epstein-Barr virus latent-cycle proteins for human CD4+ T-helper 1 responses
ANN Leen, P Meij, I Redchenko, J Middeldorp, E Bloemena, A Rickinson, ...
Journal of virology 75 (18), 8649-8659, 2001
2472001
Pathogenic roles for Epstein–Barr virus (EBV) gene products in EBV-associated proliferative disorders
JM Middeldorp, AATP Brink, AJC Van den Brule, CJLM Meijer
Critical reviews in oncology/hematology 45 (1), 1-36, 2003
2382003
Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral latent membrane protein 1 and the immunomodulatory protein galectin 9
C Keryer-Bibens, C Pioche-Durieu, C Villemant, S Souquère, N Nishi, ...
BMC cancer 6 (1), 283, 2006
2112006
EBV-positive gastric adenocarcinomas: a distinct clinicopathologic entity with a low frequency of lymph node involvement
J van Beek, A Zur Hausen, E Klein Kranenbarg, CJH van de Velde, ...
Journal of clinical oncology 22 (4), 664-670, 2004
2102004
Direct immunosuppressive effects of EBV-encoded latent membrane protein 1
DF Dukers, P Meij, MBHJ Vervoort, W Vos, RJ Scheper, CJLM Meijer, ...
The Journal of Immunology 165 (2), 663-670, 2000
2062000
Host shutoff during productive Epstein–Barr virus infection is mediated by BGLF5 and may contribute to immune evasion
M Rowe, B Glaunsinger, D van Leeuwen, J Zuo, D Sweetman, D Ganem, ...
Proceedings of the National Academy of Sciences 104 (9), 3366-3371, 2007
2052007
Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo
EHA Spaeny-Dekking, WL Hanna, AM Wolbink, PC Wever, AJ Kummer, ...
The Journal of Immunology 160 (7), 3610-3616, 1998
2031998
Cytomegalovirus (CMV) inactivation in breast milk: reassessment of pasteurization and freeze-thawing
K Hamprecht, J Maschmann, D Müller, K Dietz, I Besenthal, R Goelz, ...
Pediatric research 56 (4), 529-535, 2004
1982004
Comprehensive profiling of Epstein-Barr virus microRNAs in nasopharyngeal carcinoma
K Cosmopoulos, M Pegtel, J Hawkins, H Moffett, C Novina, J Middeldorp, ...
Journal of virology 83 (5), 2357-2367, 2009
1952009
P32/TAP, a cellular protein that interacts with EBNA-1 of Epstein–Barr virus
Y Wang, JE Finan, JM Middeldorp, SD Hayward
Virology 236 (1), 18-29, 1997
1801997
LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF‐κB activation
FJ Verweij, MAJ Van Eijndhoven, ES Hopmans, T Vendrig, T Wurdinger, ...
The EMBO journal 30 (11), 2115-2129, 2011
1662011
Epstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene Bim
K Paschos, P Smith, E Anderton, JM Middeldorp, RE White, MJ Allday
PLoS pathogens 5 (6), 2009
1642009
The amino terminus of Epstein-Barr Virus (EBV) nuclear antigen 1 contains AT hooks that facilitate the replication and partitioning of latent EBV genomes by tethering them to …
J Sears, M Ujihara, S Wong, C Ott, J Middeldorp, A Aiyar
Journal of virology 78 (21), 11487-11505, 2004
1642004
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