Joaquín Castilla
Joaquín Castilla
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Cited by
Cited by
In vitro generation of infectious scrapie prions
J Castilla, P Saá, C Hetz, C Soto
Cell 121 (2), 195-206, 2005
Caspase‐12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein
C Hetz, M Russelakis‐Carneiro, K Maundrell, J Castilla, C Soto
The EMBO journal, 2003
Production of cattle lacking prion protein
JA Richt, P Kasinathan, AN Hamir, J Castilla, T Sathiyaseelan, F Vargas, ...
Nature biotechnology 25 (1), 132-138, 2007
Detection of prions in blood
J Castilla, P Saá, C Soto
Nature medicine 11 (9), 982-985, 2005
Ultra-efficient replication of infectious prions by automated protein misfolding cyclic amplification
P Saá, J Castilla, C Soto
Journal of Biological Chemistry 281 (46), 35245-35252, 2006
Amyloids, prions and the inherent infectious nature of misfolded protein aggregates
C Soto, L Estrada, J Castilla
Trends in biochemical sciences 31 (3), 150-155, 2006
Presymptomatic detection of prions in blood
P Saá, J Castilla, C Soto
Science 313 (5783), 92-94, 2006
The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity
C Hetz, M Russelakis-Carneiro, S Wälchli, S Carboni, E Vial-Knecht, ...
Journal of Neuroscience 25 (11), 2793-2802, 2005
Prion strain mutation determined by prion protein conformational compatibility and primary structure
RC Angers, HE Kang, D Napier, S Browning, T Seward, C Mathiason, ...
Science 328 (5982), 1154-1158, 2010
Detection of amyloid fibrils in Parkinson’s disease using plasmonic chirality
J Kumar, H Eraña, E López-Martínez, N Claes, VF Martín, DM Solís, ...
Proceedings of the National Academy of Sciences 115 (13), 3225-3230, 2018
De novo induction of amyloid-β deposition in vivo
R Morales, C Duran-Aniotz, J Castilla, LD Estrada, C Soto
Molecular psychiatry 17 (12), 1347-1353, 2012
Crossing the species barrier by PrPSc replication in vitro generates unique infectious prions
J Castilla, D Gonzalez-Romero, P Saá, R Morales, J De Castro, C Soto
Cell 134 (5), 757-768, 2008
Molecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseases
R Morales, LD Estrada, R Diaz-Espinoza, D Morales-Scheihing, MC Jara, ...
Journal of Neuroscience 30 (13), 4528-4535, 2010
Cell‐free propagation of prion strains
J Castilla, R Morales, P Saá, M Barria, P Gambetti, C Soto
The EMBO journal 27 (19), 2557-2566, 2008
Pre-symptomatic detection of prions by cyclic amplification of protein misfolding
C Soto, L Anderes, S Suardi, F Cardone, J Castilla, MJ Frossard, S Peano, ...
FEBS letters 579 (3), 638-642, 2005
Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis
C Hetz, AH Lee, D Gonzalez-Romero, P Thielen, J Castilla, C Soto, ...
Proceedings of the National Academy of Sciences 105 (2), 757-762, 2008
Protein misfolding cyclic amplification for diagnosis and prion propagation studies
J Castilla, P Saá, R Morales, K Abid, K Maundrell, C Soto
Methods in enzymology 412, 3-21, 2006
Isolation and Characterization of a Proteinase K-Sensitive PrPSc Fraction
MA Pastrana, G Sajnani, B Onisko, J Castilla, R Morales, C Soto, ...
Biochemistry 45 (51), 15710-15717, 2006
A molecular switch controls interspecies prion disease transmission in mice
CJ Sigurdson, KPR Nilsson, S Hornemann, G Manco, ...
The Journal of clinical investigation 120 (7), 2590-2599, 2010
The controversial protein-only hypothesis of prion propagation
C Soto, J Castilla
Nature medicine 10 (Suppl 7), S63-S67, 2004
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