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Bryan F. Shaw
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How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein?
BF Shaw, JS Valentine
Trends in biochemical sciences 32 (2), 78-85, 2007
2972007
Destabilization of apoprotein is insufficient to explain Cu, Zn-superoxide dismutase-linked ALS pathogenesis
JA Rodriguez, BF Shaw, A Durazo, SH Sohn, PA Doucette, AM Nersissian, ...
Proceedings of the National Academy of Sciences 102 (30), 10516-10521, 2005
2082005
Abnormal SDS‐PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding
Y Shi, RA Mowery, J Ashley, M Hentz, AJ Ramirez, B Bilgicer, ...
Protein Science 21 (8), 1197-1209, 2012
1812012
Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase
ZA Oztug Durer, JA Cohlberg, P Dinh, S Padua, K Ehrenclou, S Downes, ...
PloS one 4 (3), e5004, 2009
1472009
PAI-1 promotes extracellular matrix deposition in the airways of a murine asthma model
CK Oh, B Ariue, RF Alban, B Shaw, SH Cho
Biochemical and biophysical research communications 294 (5), 1155-1160, 2002
1452002
Binding of a single zinc ion to one subunit of copper− zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein
SZ Potter, H Zhu, BF Shaw, JA Rodriguez, PA Doucette, SH Sohn, ...
Journal of the American Chemical Society 129 (15), 4575-4583, 2007
1332007
Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1
BF Shaw, HL Lelie, A Durazo, AM Nersissian, G Xu, PK Chan, EB Gralla, ...
Journal of Biological Chemistry 283 (13), 8340-8350, 2008
1032008
Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation
BF Shaw, GF Schneider, B Bilgiçer, GK Kaufman, JM Neveu, WS Lane, ...
Protein science 17 (8), 1446-1455, 2008
892008
Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase
K Sea, SH Sohn, A Durazo, Y Sheng, BF Shaw, X Cao, AB Taylor, ...
Journal of Biological Chemistry 290 (4), 2405-2418, 2015
882015
Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry
BF Shaw, A Durazo, AM Nersissian, JP Whitelegge, KF Faull, ...
Journal of Biological Chemistry 281 (26), 18167-18176, 2006
832006
Deamidation of asparagine to aspartate destabilizes Cu, Zn superoxide dismutase, accelerates fibrillization, and mirrors ALS-linked mutations
Y Shi, NR Rhodes, A Abdolvahabi, T Kohn, NP Cook, AA Marti, BF Shaw
Journal of the American Chemical Society 135 (42), 15897-15908, 2013
622013
Pathway for unfolding of ubiquitin in sodium dodecyl sulfate, studied by capillary electrophoresis
GF Schneider, BF Shaw, A Lee, E Carillho, GM Whitesides
Journal of the American Chemical Society 130 (51), 17384-17393, 2008
572008
Arresting amyloid with coulomb’s law: acetylation of ALS-linked SOD1 by aspirin impedes aggregation
A Abdolvahabi, Y Shi, NR Rhodes, NP Cook, AA Martí, BF Shaw
Biophysical journal 108 (5), 1199-1212, 2015
542015
Complexes of native ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants
BF Shaw, GF Schneider, H Arthanari, M Narovlyansky, D Moustakas, ...
Journal of the American Chemical Society 133 (44), 17681-17695, 2011
542011
A non-chromatographic method for the purification of a bivalently active monoclonal IgG antibody from biological fluids
B Bilgiçer, SW Thomas III, BF Shaw, GK Kaufman, VM Krishnamurthy, ...
Journal of the American Chemical Society 131 (26), 9361-9367, 2009
512009
Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded β-barrel at physiological temperature
A Durazo, BF Shaw, M Chattopadhyay, KF Faull, AM Nersissian, ...
Journal of biological chemistry 284 (49), 34382-34389, 2009
482009
Stochastic formation of fibrillar and amorphous superoxide dismutase oligomers linked to amyotrophic lateral sclerosis
A Abdolvahabi, Y Shi, A Chuprin, S Rasouli, BF Shaw
ACS chemical neuroscience 7 (6), 799-810, 2016
462016
Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site
NJ Alves, MM Champion, JF Stefanick, MW Handlogten, DT Moustakas, ...
Biomaterials 34 (22), 5700-5710, 2013
452013
Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability
BF Shaw, H Arthanari, M Narovlyansky, A Durazo, DP Frueh, MP Pollastri, ...
Journal of the American Chemical Society 132 (49), 17411-17425, 2010
412010
Effect of metal loading and subcellular pH on net charge of superoxide dismutase-1
Y Shi, RA Mowery, BF Shaw
Journal of molecular biology 425 (22), 4388-4404, 2013
352013
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