Karunesh Arora
Karunesh Arora
Data Science Manager at Ford Motor Company
Verified email at - Homepage
Cited by
Cited by
Large-scale allosteric conformational transitions of adenylate kinase appear to involve a population-shift mechanism
K Arora, CL Brooks III
Proceedings of the National Academy of Sciences 104 (47), 18496-18501, 2007
Critical role of magnesium ions in DNA polymerase β's closing and active site assembly
L Yang, K Arora, WA Beard, SH Wilson, T Schlick
Journal of the american chemical society 126 (27), 8441-8453, 2004
Regulation of DNA repair fidelity by molecular checkpoints:“gates” in DNA polymerase β's substrate selection
R Radhakrishnan, K Arora, Y Wang, WA Beard, SH Wilson, T Schlick
Biochemistry 45 (51), 15142-15156, 2006
Mismatch-induced conformational distortions in polymerase β support an induced-fit mechanism for fidelity
K Arora, WA Beard, SH Wilson, T Schlick
Biochemistry 44 (40), 13328-13341, 2005
Functionally important conformations of the Met20 loop in dihydrofolate reductase are populated by rapid thermal fluctuations
K Arora, CL Brooks Iii
Journal of the American Chemical Society 131 (15), 5642-5647, 2009
In Silico Evidence for DNA Polymerase- β’s Substrate-Induced Conformational Change
K Arora, T Schlick
Biophysical journal 87 (5), 3088-3099, 2004
Harmonic Fourier beads method for studying rare events on rugged energy surfaces
IV Khavrutskii, K Arora, CL Brooks
The Journal of chemical physics 125 (17), 2006
Deoxyadenosine sugar puckering pathway simulated by the stochastic difference equation algorithm
K Arora, T Schlick
Chemical physics letters 378 (1-2), 1-8, 2003
Perspective: pre-chemistry conformational changes in DNA polymerase mechanisms
T Schlick, K Arora, WA Beard, SH Wilson
Theoretical chemistry accounts 131, 1-8, 2012
Conformational transition pathway of polymerase β/DNA upon binding correct incoming substrate
K Arora, T Schlick
The Journal of Physical Chemistry B 109 (11), 5358-5367, 2005
Multiple intermediates, diverse conformations, and cooperative conformational changes underlie the catalytic hydride transfer reaction of dihydrofolate reductase
K Arora, CL Brooks
Dynamics in enzyme catalysis, 165-187, 2013
Modulation of frustration in folding by sequence permutation
RP Nobrega, K Arora, SV Kathuria, R Graceffa, RA Barrea, L Guo, ...
Proceedings of the National Academy of Sciences 111 (29), 10562-10567, 2014
Subtle but variable conformational rearrangements in the replication cycle of Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) may accommodate lesion bypass
Y Wang, K Arora, T Schlick
Protein science 15 (1), 135-151, 2006
Conformational dynamics in human purine nucleoside phosphorylase with reactants and transition-state analogues
JS Hirschi, K Arora, CL Brooks III, VL Schramm
The Journal of Physical Chemistry B 114 (49), 16263-16272, 2010
K+/Na+ Selectivity in Toy Cation Binding Site Models Is Determined by the ‘Host’
DL Bostick, K Arora, CL Brooks III
Biophysical journal 96 (10), 3887-3896, 2009
Mismatched base-pair simulations for ASFV pol X/DNA complexes help interpret frequent G• G misincorporation
BAS Benítez, K Arora, L Balistreri, T Schlick
Journal of molecular biology 384 (5), 1086-1097, 2008
Hexameric helicase deconstructed: interplay of conformational changes and substrate coupling
K Yoshimoto, K Arora, CL Brooks
Biophysical journal 98 (8), 1449-1457, 2010
pH-induced stability switching of the bacteriophage HK97 maturation pathway
ER May, K Arora, CL Brooks III
Journal of the American Chemical Society 136 (8), 3097-3107, 2014
Frustration and folding of a TIM barrel protein
KT Halloran, Y Wang, K Arora, S Chakravarthy, TC Irving, O Bilsel, ...
Proceedings of the National Academy of Sciences 116 (33), 16378-16383, 2019
Regulation of calreticulin–major histocompatibility complex (MHC) class I interactions by ATP
SJ Wijeyesakere, JK Gagnon, K Arora, CL Brooks III, M Raghavan
Proceedings of the National Academy of Sciences 112 (41), E5608-E5617, 2015
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