| Kv1. 3 channels are a therapeutic target for T cell-mediated autoimmune diseases C Beeton, H Wulff, NE Standifer, P Azam, KM Mullen, MW Pennington, ... Proceedings of the National Academy of Sciences 103 (46), 17414-17419, 2006 | 608 | 2006 |
| K+ channels as targets for specific immunomodulation KG Chandy, H Wulff, C Beeton, M Pennington, GA Gutman, MD Cahalan Trends in pharmacological sciences 25 (5), 280-289, 2004 | 556 | 2004 |
| The voltage-gated Kv1. 3 K+ channel in effector memory T cells as new target for MS H Wulff, PA Calabresi, R Allie, S Yun, M Pennington, C Beeton, ... Journal of Clinical Investigation 111 (11), 1703-1713, 2003 | 549 | 2003 |
| Enhanced cardiomyocyte NLRP3 inflammasome signaling promotes atrial fibrillation C Yao, T Veleva, L Scott Jr, S Cao, L Li, G Chen, P Jeyabal, X Pan, ... Circulation 138 (20), 2227-2242, 2018 | 444 | 2018 |
| Selective blockade of T lymphocyte K+ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis C Beeton, H Wulff, J Barbaria, O Clot-Faybesse, M Pennington, D Bernard, ... Proceedings of the national academy of sciences 98 (24), 13942-13947, 2001 | 442 | 2001 |
| Targeting effector memory T cells with a selective peptide inhibitor of Kv1. 3 channels for therapy of autoimmune diseases C Beeton, MW Pennington, H Wulff, S Singh, D Nugent, G Crossley, ... Molecular pharmacology 67 (4), 1369-1381, 2005 | 341 | 2005 |
| Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases V Chi, MW Pennington, RS Norton, EJ Tarcha, LM Londono, ... Toxicon 59 (4), 529-546, 2012 | 257 | 2012 |
| Selective blocking of voltage-gated K+ channels improves experimental autoimmune encephalomyelitis and inhibits T cell activation C Beeton, J Barbaria, P Giraud, J Devaux, AM Benoliel, M Gola, ... The Journal of Immunology 166 (2), 936-944, 2001 | 253 | 2001 |
| Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1. 3 channel block MP Matheu, C Beeton, A Garcia, V Chi, S Rangaraju, O Safrina, ... Immunity 29 (4), 602-614, 2008 | 244 | 2008 |
| The voltage-gated potassium channel Kv1. 3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain H Rus, CA Pardo, L Hu, E Darrah, C Cudrici, T Niculescu, F Niculescu, ... Proceedings of the National Academy of Sciences 102 (31), 11094-11099, 2005 | 228 | 2005 |
| Kv1. 3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators J Vennekamp, H Wulff, C Beeton, PA Calabresi, S Grissmer, W Hänsel, ... Molecular pharmacology 65 (6), 1364-1374, 2004 | 195 | 2004 |
| Potassium channels as therapeutic targets for autoimmune disorders. H Wulff, C Beeton, KG Chandy Current opinion in drug discovery & development 6 (5), 640-647, 2003 | 190 | 2003 |
| Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis H Mkhikian, A Grigorian, CF Li, HL Chen, B Newton, RW Zhou, C Beeton, ... Nature communications 2 (1), 334, 2011 | 185 | 2011 |
| Detection of functional matrix metalloproteinases by zymography X Hu, C Beeton JoVE (Journal of Visualized Experiments), e2445, 2010 | 178 | 2010 |
| AAV-CRISPR gene editing is negated by pre-existing immunity to Cas9 A Li, MR Tanner, CM Lee, AE Hurley, M De Giorgi, KE Jarrett, TH Davis, ... Molecular Therapy 28 (6), 1432-1441, 2020 | 170 | 2020 |
| Engineering a stable and selective peptide blocker of the Kv1. 3 channel in T lymphocytes MW Pennington, C Beeton, CA Galea, BJ Smith, V Chi, KP Monaghan, ... Molecular pharmacology 75 (4), 762-773, 2009 | 159 | 2009 |
| Potassium channels, memory T cells, and multiple sclerosis C Beeton, KG Chandy The Neuroscientist 11 (6), 550-562, 2005 | 145 | 2005 |
| Durable pharmacological responses from the peptide ShK-186, a specific Kv1. 3 channel inhibitor that suppresses T cell mediators of autoimmune disease EJ Tarcha, V Chi, EJ Muñoz-Elías, D Bailey, LM Londono, SK Upadhyay, ... Journal of Pharmacology and Experimental Therapeutics 342 (3), 642-653, 2012 | 142 | 2012 |
| A novel fluorescent toxin to detect and investigate Kv1. 3 channel up-regulation in chronically activated T lymphocytes C Beeton, H Wulff, S Singh, S Botsko, G Crossley, GA Gutman, ... Journal of Biological Chemistry 278 (11), 9928-9937, 2003 | 139 | 2003 |
| Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases C Beeton, M W Pennington, R S Norton Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets …, 2011 | 121 | 2011 |
Mike PenningtonVice President and C.S.OVerified email at ambiopharm.com
