Lacramioara Bintu
Lacramioara Bintu
Assistant Professor of Bioengineering
Verified email at - Homepage
Cited by
Cited by
Transcriptional regulation by the numbers: models
L Bintu, NE Buchler, HG Garcia, U Gerland, T Hwa, J Kondev, R Phillips
Current opinion in genetics & development 15 (2), 116-124, 2005
Transcriptional regulation by the numbers: applications
L Bintu, NE Buchler, HG Garcia, U Gerland, T Hwa, J Kondev, T Kuhlman, ...
Current opinion in genetics & development 15 (2), 125-135, 2005
Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II
C Hodges, L Bintu, L Lubkowska, M Kashlev, C Bustamante
Science 325 (5940), 626-628, 2009
Dynamics of epigenetic regulation at the single-cell level
L Bintu
Science 351 (6274), 720-724, 2016
Nucleosomal elements that control the topography of the barrier to transcription
L Bintu, T Ishibashi, M Dangkulwanich, YY Wu, L Lubkowska, M Kashlev, ...
Cell 151 (4), 738-749, 2012
The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes
L Bintu, M Kopaczynska, C Hodges, L Lubkowska, M Kashlev, ...
Nature structural & molecular biology 18 (12), 1394-1399, 2011
Nascent RNA structure modulates the transcriptional dynamics of RNA polymerases
B Zamft, L Bintu, T Ishibashi, C Bustamante
Proceedings of the National Academy of Sciences 109 (23), 8948-8953, 2012
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements
J Tycko, M Wainberg, GK Marinov, O Ursu, GT Hess, BK Ego, Aradhana, ...
Nature communications 10 (1), 4063, 2019
Molecular mechanisms of transcription through single-molecule experiments
M Dangkulwanich, T Ishibashi, L Bintu, C Bustamante
Chemical reviews 114 (6), 3203-3223, 2014
High-throughput discovery and characterization of human transcriptional effectors
J Tycko, N DelRosso, GT Hess, A Banerjee, A Mukund, MV Van, BK Ego, ...
Cell 183 (7), 2020
Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
MG Durrant, A Fanton, J Tycko, M Hinks, SS Chandrasekaran, NT Perry, ...
Nature biotechnology 41 (4), 488-499, 2023
Mapping chromatin modifications at the single cell level
CH Ludwig, L Bintu
Development 146 (12), dev170217, 2019
Large-scale mapping and mutagenesis of human transcriptional effector domains
N DelRosso, J Tycko, P Suzuki, C Andrews, Aradhana, A Mukund, ...
Nature 616 (7956), 365-372, 2023
The sound of silence: Transgene silencing in mammalian cell engineering
A Cabrera, HI Edelstein, F Glykofrydis, KS Love, S Palacios, J Tycko, ...
Cell systems 13 (12), 950-973, 2022
Nanobody-mediated control of gene expression and epigenetic memory
MV Van, T Fujimori, L Bintu
Nature Communications 12 (1), 537, 2021
Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells
S Lensch, MH Herschl, CH Ludwig, J Sinha, MM Hinks, A Mukund, ...
Elife 11, e75115, 2022
Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project
J Dekker, F Alber, S Aufmkolk, BJ Beliveau, BG Bruneau, AS Belmont, ...
Molecular cell, 2023
Large-scale discovery of recombinases for integrating DNA into the human genome
MG Durrant, A Fanton, J Tycko, M Hinks, SS Chandrasekaran, NT Perry, ...
BioRxiv, 2021.11. 05.467528, 2021
Advancing towards a global mammalian gene regulation model through single-cell analysis and synthetic biology
J Tycko, MV Van, MB Elowitz, L Bintu
Current Opinion in Biomedical Engineering 4, 174-193, 2017
High-throughput functional characterization of combinations of transcriptional activators and repressors
AX Mukund, J Tycko, SJ Allen, SA Robinson, C Andrews, J Sinha, ...
Cell Systems 14 (9), 746-763. e5, 2023
The system can't perform the operation now. Try again later.
Articles 1–20