| Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3484 | 2010 |
| The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B Gene P Honkakoski, I Zelko, T Sueyoshi, M Negishi Molecular and cellular biology 18 (10), 5652-5658, 1998 | 894 | 1998 |
| The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene T Sueyoshi, T Kawamoto, I Zelko, P Honkakoski, M Negishi Journal of Biological Chemistry 274 (10), 6043-6046, 1999 | 842 | 1999 |
| Phenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the CYP2B Gene T Kawamoto, T Sueyoshi, I Zelko, R Moore, K Washburn, M Negishi Molecular and cellular biology 19 (9), 6318-6322, 1999 | 693 | 1999 |
| Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital A Ueda, HK Hamadeh, HK Webb, Y Yamamoto, T Sueyoshi, CA Afshari, ... Molecular pharmacology 61 (1), 1-6, 2002 | 535 | 2002 |
| Phenobarbital response elements of cytochrome P450 genes and nuclear receptors T Sueyoshi, M Negishi Annual review of pharmacology and toxicology 41 (1), 123-143, 2001 | 491 | 2001 |
| The phenobarbital response enhancer module in the human bilirubin UDP‐glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR J Sugatani, H Kojima, A Ueda, S Kakizaki, K Yoshinari, QH Gong, ... Hepatology 33 (5), 1232-1238, 2001 | 460 | 2001 |
| Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers SR Faucette, TC Zhang, R Moore, T Sueyoshi, CJ Omiecinski, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 72-80, 2007 | 337 | 2007 |
| Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia J Sugatani, K Yamakawa, K Yoshinari, T Machida, H Takagi, M Mori, ... Biochemical and biophysical research communications 292 (2), 492-497, 2002 | 271 | 2002 |
| A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression H Wang, S Faucette, T Sueyoshi, R Moore, S Ferguson, M Negishi, ... Journal of Biological Chemistry 278 (16), 14146-14152, 2003 | 257 | 2003 |
| Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver EJ Squires, T Sueyoshi, M Negishi Journal of Biological Chemistry 279 (47), 49307-49314, 2004 | 239 | 2004 |
| Drug-activated nuclear receptors CAR and PXR P Honkakoski, T Sueyoshi, M Negishi Annals of medicine 35 (3), 172-182, 2003 | 229 | 2003 |
| Cytoplasmic accumulation of the nuclear receptor CAR by a tetratricopeptide repeat protein in HepG2 cells K Kobayashi, T Sueyoshi, K Inoue, R Moore, M Negishi Molecular pharmacology 64 (5), 1069-1075, 2003 | 228 | 2003 |
| Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP … J Sugatani, S Nishitani, K Yamakawa, K Yoshinari, T Sueyoshi, M Negishi, ... Molecular pharmacology 67 (3), 845-855, 2005 | 225 | 2005 |
| Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor SR Faucette, T Sueyoshi, CM Smith, M Negishi, EL LeCluyse, H Wang Journal of Pharmacology and Experimental Therapeutics 317 (3), 1200-1209, 2006 | 221 | 2006 |
| Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling S Mutoh, M Sobhany, R Moore, L Perera, L Pedersen, T Sueyoshi, ... Science signaling 6 (274), ra31-ra31, 2013 | 212 | 2013 |
| Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver K Nakamura, R Moore, M Negishi, T Sueyoshi Journal of Biological Chemistry 282 (13), 9768-9776, 2007 | 202 | 2007 |
| The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver I Zelko, T Sueyoshi, T Kawamoto, R Moore, M Negishi Molecular and cellular biology 21 (8), 2838-2846, 2001 | 189 | 2001 |
| Crystal Structure of the Sulfotransferase Domain of Human Heparan SulfateN-Deacetylase/N-Sulfotransferase 1 Y Kakuta, T Sueyoshi, M Negishi, LC Pedersen Journal of Biological Chemistry 274 (16), 10673-10676, 1999 | 186 | 1999 |
| Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin H Wang, S Faucette, R Moore, T Sueyoshi, M Negishi, E LeCluyse Journal of Biological Chemistry 279 (28), 29295-29301, 2004 | 184 | 2004 |
