| Self‐assembled DNA nanoclews for the efficient delivery of CRISPR–Cas9 for genome editing W Sun, W Ji, JM Hall, Q Hu, C Wang, CL Beisel, Z Gu Angewandte Chemie 127 (41), 12197-12201, 2015 | 643 | 2015 |
| Programmable removal of bacterial strains by use of genome-targeting CRISPR-Cas systems AA Gomaa, HE Klumpe, ML Luo, K Selle, R Barrangou, CL Beisel MBio 5 (1), 10.1128/mbio. 00928-13, 2014 | 441 | 2014 |
| Guide RNA functional modules direct Cas9 activity and orthogonality AE Briner, PD Donohoue, AA Gomaa, K Selle, EM Slorach, CH Nye, ... Molecular cell 56 (2), 333-339, 2014 | 373 | 2014 |
| Base pairing small RNAs and their roles in global regulatory networks CL Beisel, G Storz FEMS microbiology reviews 34 (5), 866-882, 2010 | 344 | 2010 |
| Identifying and visualizing functional PAM diversity across CRISPR-Cas systems RT Leenay, KR Maksimchuk, RA Slotkowski, RN Agrawal, AA Gomaa, ... Molecular cell 62 (1), 137-147, 2016 | 332 | 2016 |
| Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression ML Luo, AS Mullis, RT Leenay, CL Beisel Nucleic acids research 43 (1), 674-681, 2015 | 286 | 2015 |
| The base-pairing RNA spot 42 participates in a multioutput feedforward loop to help enact catabolite repression in Escherichia coli CL Beisel, G Storz Molecular cell 41 (3), 286-297, 2011 | 242 | 2011 |
| Rapid and scalable characterization of CRISPR technologies using an E. coli cell-free transcription-translation system R Marshall, CS Maxwell, SP Collins, T Jacobsen, ML Luo, MB Begemann, ... Molecular cell 69 (1), 146-157. e3, 2018 | 210 | 2018 |
| CRISPR technologies and the search for the PAM-free nuclease D Collias, CL Beisel Nature communications 12 (1), 555, 2021 | 195 | 2021 |
| Deciphering, communicating, and engineering the CRISPR PAM RT Leenay, CL Beisel Journal of molecular biology 429 (2), 177-191, 2017 | 183 | 2017 |
| Model‐guided design of ligand‐regulated RNAi for programmable control of gene expression CL Beisel, TS Bayer, KG Hoff, CD Smolke Molecular systems biology 4 (1), 224, 2008 | 151 | 2008 |
| Design principles for riboswitch function CL Beisel, CD Smolke PLoS computational biology 5 (4), e1000363, 2009 | 150 | 2009 |
| Current and future prospects for CRISPR‐based tools in bacteria ML Luo, RT Leenay, CL Beisel Biotechnology and bioengineering 113 (5), 930-943, 2016 | 143 | 2016 |
| CRISPR RNA-dependent binding and cleavage of endogenous RNAs by the Campylobacter jejuni Cas9 G Dugar, RT Leenay, SK Eisenbart, T Bischler, BU Aul, CL Beisel, ... Molecular cell 69 (5), 893-905. e7, 2018 | 137 | 2018 |
| Multiple factors dictate target selection by Hfq‐binding small RNAs CL Beisel, TB Updegrove, BJ Janson, G Storz The EMBO journal 31 (8), 1961-1974, 2012 | 127 | 2012 |
| Bacterial adaptation to the host's diet is a key evolutionary force shaping Drosophila-Lactobacillus symbiosis ME Martino, P Joncour, R Leenay, H Gervais, M Shah, S Hughes, B Gillet, ... Cell host & microbe 24 (1), 109-119. e6, 2018 | 122 | 2018 |
| A CRISPR design for next-generation antimicrobials CL Beisel, AA Gomaa, R Barrangou Genome biology 15 (11), 1-4, 2014 | 122 | 2014 |
| Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing CL Beisel, YY Chen, SJ Culler, KG Hoff, CD Smolke Nucleic acids research 39 (7), 2981-2994, 2011 | 122 | 2011 |
| Synthetic biology approaches to engineer probiotics and members of the human microbiota for biomedical applications JR Bober, CL Beisel, NU Nair Annual review of biomedical engineering 20, 277-300, 2018 | 101 | 2018 |
| Short DNA containing χ sites enhances DNA stability and gene expression in E. coli cell‐free transcription–translation systems R Marshall, CS Maxwell, SP Collins, CL Beisel, V Noireaux Biotechnology and bioengineering 114 (9), 2137-2141, 2017 | 99 | 2017 |
