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Sinéad M Ryan
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Advances in PEGylation of important biotech molecules: delivery aspects
SM Ryan, G Mantovani, X Wang, DM Haddleton, DJ Brayden
Expert opinion on drug delivery 5 (4), 371-383, 2008
3952008
Antibacterial effects of poly (2-(dimethylamino ethyl) methacrylate) against selected gram-positive and gram-negative bacteria
LAB Rawlinson, SM Ryan, G Mantovani, JA Syrett, DM Haddleton, ...
Biomacromolecules 11 (2), 443-453, 2010
2452010
Screening for and identification of starch-, amylopectin-, and pullulan-degrading activities in bifidobacterial strains
SM Ryan, GF Fitzgerald, D van Sinderen
Applied and environmental microbiology 72 (8), 5289-5296, 2006
2212006
Direct peptide bioconjugation/PEGylation at tyrosine with linear and branched polymeric diazonium salts
MW Jones, G Mantovani, CA Blindauer, SM Ryan, X Wang, DJ Brayden, ...
Journal of the American Chemical Society 134 (17), 7406-7413, 2012
1482012
Transcriptional Regulation and Characterization of a Novel β-Fructofuranosidase-Encoding Gene from Bifidobacterium breve UCC2003
SM Ryan, GF Fitzgerald, D van Sinderen
Applied and environmental microbiology 71 (7), 3475-3482, 2005
1242005
Characterization of ApuB, an Extracellular Type II Amylopullulanase from Bifidobacterium breve UCC2003
M O'Connell Motherway, GF Fitzgerald, S Neirynck, S Ryan, L Steidler, ...
Applied and environmental microbiology 74 (20), 6271-6279, 2008
1222008
Oral delivery strategies for nutraceuticals: Delivery vehicles and absorption enhancers
JP Gleeson, SM Ryan, DJ Brayden
Trends in Food Science & Technology 53, 90-101, 2016
1162016
Phosphine-mediated one-pot thiol–ene “click” approach to polymer–protein conjugates
MW Jones, G Mantovani, SM Ryan, X Wang, DJ Brayden, DM Haddleton
Chemical communications, 5272-5274, 2009
1062009
Conjugation of salmon calcitonin to a combed-shaped end functionalized poly (poly (ethylene glycol) methyl ether methacrylate) yields a bioactive stable conjugate
SM Ryan, X Wang, G Mantovani, CT Sayers, DM Haddleton, DJ Brayden
Journal of Controlled Release 135 (1), 51-59, 2009
922009
An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis
SM Ryan, J McMorrow, A Umerska, HB Patel, KN Kornerup, L Tajber, ...
Journal of controlled release 167 (2), 120-129, 2013
822013
Progress in the delivery of nanoparticle constructs: towards clinical translation
SM Ryan, DJ Brayden
Current opinion in pharmacology 18, 120-128, 2014
522014
In vitro and in vivo characterisation of a novel peptide delivery system: amphiphilic polyelectrolyte–salmon calcitonin nanocomplexes
WP Cheng, C Thompson, SM Ryan, T Aguirre, L Tetley, DJ Brayden
Journal of controlled release 147 (2), 289-297, 2010
512010
Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models
JP Gleeson, DJ Brayden, SM Ryan
European Journal of Pharmaceutics and Biopharmaceutics 115, 276-284, 2017
502017
Stability, toxicity and intestinal permeation enhancement of two food-derived antihypertensive tripeptides, Ile-Pro-Pro and Leu-Lys-Pro
JP Gleeson, J Heade, SM Ryan, DJ Brayden
Peptides 71, 1-7, 2015
462015
Dexamethasone–pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers
S Keely, SM Ryan, DM Haddleton, A Limer, G Mantovani, EP Murphy, ...
Journal of controlled release 135 (1), 35-43, 2009
462009
PK/PD modelling of comb-shaped PEGylated salmon calcitonin conjugates of differing molecular weights
SM Ryan, JM Frías, X Wang, CT Sayers, DM Haddleton, DJ Brayden
Journal of controlled release 149 (2), 126-132, 2011
372011
Site-specific N-terminus conjugation of poly (mPEG 1100) methacrylates to salmon calcitonin: synthesis and preliminary biological evaluation
CT Sayers, G Mantovani, SM Ryan, RK Randev, O Keiper, ...
Soft Matter 5 (16), 3038-3046, 2009
332009
Impact of amino acid replacements on in vitro permeation enhancement and cytotoxicity of the intestinal absorption promoter, melittin
S Maher, M Devocelle, S Ryan, S McClean, DJ Brayden
International journal of pharmaceutics 387 (1-2), 154-160, 2010
312010
Application of Box-Behnken experimental design for the formulation and optimisation of selenomethionine-loaded chitosan nanoparticles coated with zein for oral delivery
G Vozza, M Danish, HJ Byrne, JM Frías, SM Ryan
International journal of pharmaceutics 551 (1-2), 257-269, 2018
292018
Sodium caprate enables the blood pressure-lowering effect of Ile-Pro-Pro and Leu-Lys-Pro in spontaneously hypertensive rats by indirectly overcoming PepT1 inhibition
JP Gleeson, JM Frías, SM Ryan, DJ Brayden
European Journal of Pharmaceutics and Biopharmaceutics 128, 179-187, 2018
282018
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