| Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts H Takayanagi, S Kim, T Koga, H Nishina, M Isshiki, H Yoshida, A Saiura, ... Developmental cell 3 (6), 889-901, 2002 | 2778 | 2002 |
| TAK1 is a ubiquitin-dependent kinase of MKK and IKK C Wang, L Deng, M Hong, GR Akkaraju, J Inoue, ZJ Chen Nature 412 (6844), 346-351, 2001 | 2659 | 2001 |
| The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway J Ninomiya-Tsuji, K Kishimoto, A Hiyama, J Inoue, Z Cao, K Matsumoto Nature 398 (6724), 252-256, 1999 | 1483 | 1999 |
| Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible … T Kawai, O Takeuchi, T Fujita, J Inoue, PF Mühlradt, S Sato, K Hoshino, ... The Journal of Immunology 167 (10), 5887-5894, 2001 | 1439 | 2001 |
| Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 T Kawai, S Sato, KJ Ishii, C Coban, H Hemmi, M Yamamoto, K Terai, ... Nature immunology 5 (10), 1061-1068, 2004 | 1306 | 2004 |
| Severe osteopetrosis, defective interleukin‐1 signalling and lymph node organogenesis in TRAF6‐deficient mice A Naito, S Azuma, S Tanaka, T Miyazaki, S Takaki, K Takatsu, K Nakao, ... Genes to Cells 4 (6), 353-362, 1999 | 788 | 1999 |
| Induction of interleukin-2 receptor gene expression by p40x protein encoded by human T cell leukemia virus type I J INOUE EMBO J 5, 2883-2888, 1992 | 595* | 1992 |
| Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1. J Inoue, M Seiki, T Taniguchi, S Tsuru, M Yoshida The EMBO Journal 5 (11), 2883, 1986 | 595 | 1986 |
| Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region T Ishida, S Mizushima, S Azuma, N Kobayashi, T Tojo, K Suzuki, ... Journal of Biological Chemistry 271 (46), 28745-28748, 1996 | 588 | 1996 |
| The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance T Akiyama, Y Shimo, H Yanai, J Qin, D Ohshima, Y Maruyama, Y Asaumi, ... Immunity 29 (3), 423-437, 2008 | 564 | 2008 |
| Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling J Inoue, T Ishida, N Tsukamoto, N Kobayashi, A Naito, S Azuma, ... Experimental cell research 254 (1), 14-24, 2000 | 551 | 2000 |
| Segregation of TRAF6‐mediated signaling pathways clarifies its role in osteoclastogenesis N Kobayashi, Y Kadono, A Naito, K Matsumoto, T Yamamoto, S Tanaka, ... The EMBO journal 20 (6), 1271-1280, 2001 | 537 | 2001 |
| Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation F Ikeda, R Nishimura, T Matsubara, S Tanaka, J Inoue, SV Reddy, K Hata, ... Journal of Clinical Investigation 114 (4), 475, 2004 | 524 | 2004 |
| Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering M Maruyama, H Shibuya, H Harada, M Hatakeyama, M Seiki, T Fujita, ... Cell 48 (2), 343-350, 1987 | 501 | 1987 |
| The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator Y Hikosaka, T Nitta, I Ohigashi, K Yano, N Ishimaru, Y Hayashi, ... Immunity 29 (3), 438-450, 2008 | 465 | 2008 |
| IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinases T Shimada, T Kawai, K Takeda, M Matsumoto, J Inoue, Y Tatsumi, ... International immunology 11 (8), 1357-1362, 1999 | 465 | 1999 |
| Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not Toll/IL-1 receptor domain-containing adaptor-inducing IFN-β (TRIF)-dependent … J Gohda, T Matsumura, J Inoue The Journal of Immunology 173 (5), 2913-2917, 2004 | 420 | 2004 |
| Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell … M Yamamoto, S Matsuyama, X Li, M Takeda, Y Kawaguchi, J Inoue, ... Antimicrobial agents and chemotherapy 60 (11), 6532-6539, 2016 | 381 | 2016 |
| Post-transcriptional regulator (rex) of HTLV-1 initiates expression of viral structural proteins but suppresses expression of regulatory proteins. M Hidaka, J Inoue, M Yoshida, M Seiki The EMBO journal 7 (2), 519, 1988 | 357 | 1988 |
| Dependence of self-tolerance on TRAF6-directed development of thymic stroma T Akiyama, S Maeda, S Yamane, K Ogino, M Kasai, F Kajiura, ... Science 308 (5719), 248-251, 2005 | 349 | 2005 |
