| Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia M Fabbri, A Bottoni, M Shimizu, R Spizzo, MS Nicoloso, S Rossi, ... Jama 305 (1), 59-67, 2011 | 380 | 2011 |
| microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival S Rossi, M Shimizu, E Barbarotto, MS Nicoloso, F Dimitri, D Sampath, ... Blood, The Journal of the American Society of Hematology 116 (6), 945-952, 2010 | 307 | 2010 |
| Nucleoside analogs: molecular mechanisms signaling cell death B Ewald, D Sampath, W Plunkett Oncogene 27 (50), 6522-6537, 2008 | 298 | 2008 |
| Mechanisms of apoptosis induction by nucleoside analogs D Sampath, VA Rao, W Plunkett Oncogene 22 (56), 9063-9074, 2003 | 268 | 2003 |
| Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia D Sampath, C Liu, K Vasan, M Sulda, VK Puduvalli, WG Wierda, ... Blood, The Journal of the American Society of Hematology 119 (5), 1162-1172, 2012 | 254 | 2012 |
| H2AX phosphorylation marks gemcitabine-induced stalled replication forks and their collapse upon S-phase checkpoint abrogation B Ewald, D Sampath, W Plunkett Molecular cancer therapeutics 6 (4), 1239-1248, 2007 | 232 | 2007 |
| Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial D Sampath, J Cortes, Z Estrov, M Du, Z Shi, M Andreeff, V Gandhi, ... Blood 107 (6), 2517-2524, 2006 | 180 | 2006 |
| S-Phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine Z Shi, A Azuma, D Sampath, YX Li, P Huang, W Plunkett Cancer research 61 (3), 1065-1072, 2001 | 180 | 2001 |
| The BTK inhibitor ARQ 531 targets ibrutinib-resistant CLL and Richter transformation SD Reiff, R Mantel, LL Smith, JT Greene, EM Muhowski, CA Fabian, ... Cancer discovery 8 (10), 1300-1315, 2018 | 158 | 2018 |
| Effects of nerve growth factor on glutathione peroxidase and catalase in PC 12 cells D Sampath, GR Jackson, K Werrbach‐Perez, JR Perez‐Polo Journal of neurochemistry 62 (6), 2476-2479, 1994 | 156 | 1994 |
| miRNAs and their potential for use against cancer and other diseases E Tili, JJ Michaille, V Gandhi, W Plunkett, D Sampath, GA Calin Future oncology 3 (5), 521-537, 2007 | 126 | 2007 |
| BRD4 profiling identifies critical chronic lymphocytic leukemia oncogenic circuits and reveals sensitivity to PLX51107, a novel structurally distinct BET inhibitor HG Ozer, D El-Gamal, B Powell, ZA Hing, JS Blachly, B Harrington, ... Cancer discovery 8 (4), 458-477, 2018 | 124 | 2018 |
| Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation D Sampath, GA Calin, VK Puduvalli, G Gopisetty, C Taccioli, CG Liu, ... Blood, The Journal of the American Society of Hematology 113 (16), 3744-3753, 2009 | 107 | 2009 |
| TRAIL-induced apoptosis in gliomas is enhanced by Akt-inhibition and is independent of JNK activation VK Puduvalli, D Sampath, JM Bruner, J Nangia, R Xu, AP Kyritsis Apoptosis 10, 233-243, 2005 | 92 | 2005 |
| XPO1 inhibition using selinexor synergizes with chemotherapy in acute myeloid leukemia by targeting DNA repair and restoring topoisomerase IIα to the nucleus P Ranganathan, T Kashyap, X Yu, X Meng, TH Lai, B McNeil, ... Clinical Cancer Research 22 (24), 6142-6152, 2016 | 90 | 2016 |
| Epigenetic regulation of CD133/PROM1 expression in glioma stem cells by Sp1/myc and promoter methylation G Gopisetty, J Xu, D Sampath, H Colman, VK Puduvalli Oncogene 32 (26), 3119-3129, 2013 | 88 | 2013 |
| Inhibition of cyclin-dependent kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: dysregulation by 7-hydroxystaurosporine D Sampath, Z Shi, W Plunkett Molecular pharmacology 62 (3), 680-688, 2002 | 84 | 2002 |
| Efficacy of onalespib, a long-acting second-generation HSP90 inhibitor, as a single agent and in combination with temozolomide against malignant gliomas A Canella, AM Welker, JY Yoo, J Xu, FS Abas, D Kesanakurti, ... Clinical Cancer Research 23 (20), 6215-6226, 2017 | 70 | 2017 |
| HDAC inhibition induces microRNA-182, which targets RAD51 and impairs HR repair to sensitize cells to sapacitabine in acute myelogenous leukemia TH Lai, B Ewald, A Zecevic, C Liu, M Sulda, D Papaioannou, R Garzon, ... Clinical cancer research 22 (14), 3537-3549, 2016 | 66 | 2016 |
| ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue–Induced stalled replication forks and contribute to drug resistance B Ewald, D Sampath, W Plunkett Cancer research 68 (19), 7947-7955, 2008 | 63 | 2008 |
john C. ByrdDistinguished University Professor, The Ohio State UniversityVerified email at osumc.edu
