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Paul Conroy
Paul Conroy
Associate Manager @ Regeneron
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Cited by
Year
Antibody production, design and use for biosensor-based applications
PJ Conroy, S Hearty, P Leonard, RJ O’Kennedy
Seminars in cell & developmental biology 20 (1), 10-26, 2009
3772009
Aberrant PSA glycosylation—a sweet predictor of prostate cancer
S Gilgunn, PJ Conroy, R Saldova, PM Rudd, RJ O'kennedy
Nature Reviews Urology 10 (2), 99-107, 2013
2502013
A tale of two specificities: bispecific antibodies for therapeutic and diagnostic applications
H Byrne, PJ Conroy, JC Whisstock, RJ O’Kennedy
Trends in biotechnology 31 (11), 621-632, 2013
2032013
Structure of the poly-C9 component of the complement membrane attack complex
NV Dudkina, BA Spicer, CF Reboul, PJ Conroy, N Lukoyanova, ...
Nature communications 7 (1), 10588, 2016
1252016
The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1
SS Pang, C Bayly-Jones, M Radjainia, BA Spicer, RHP Law, AW Hodel, ...
Nature communications 10 (1), 4288, 2019
632019
Homodimerization attenuates the anti-inflammatory activity of interleukin-37
AM Ellisdon, CA Nold-Petry, L D’Andrea, SX Cho, JC Lao, I Rudloff, ...
Science immunology 2 (8), eaaj1548, 2017
612017
Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA
CJ Holland, RM Crean, JM Pentier, B de Wet, A Lloyd, V Srikannathasan, ...
The Journal of clinical investigation 130 (5), 2673-2688, 2020
562020
The first transmembrane region of complement component-9 acts as a brake on its self-assembly
BA Spicer, RHP Law, TT Caradoc-Davies, SM Ekkel, C Bayly-Jones, ...
Nature Communications 9 (1), 3266, 2018
512018
Surface plasmon resonance for vaccine design and efficacy studies: recent applications and future trends
S Hearty, PJ Conroy, BV Ayyar, B Byrne, R O’Kennedy
Expert review of vaccines 9 (6), 645-664, 2010
502010
Tranexamic acid is an active site inhibitor of urokinase plasminogen activator
G Wu, BA Mazzitelli, AJ Quek, MJ Veldman, PJ Conroy, ...
Blood advances 3 (5), 729-733, 2019
382019
X-ray crystal structure of plasmin with tranexamic acid–derived active site inhibitors
RHP Law, G Wu, EWW Leung, K Hidaka, AJ Quek, TT Caradoc-Davies, ...
Blood advances 1 (12), 766-771, 2017
362017
Electrochemiluminescence platform for the detection of C-reactive proteins: application of recombinant antibody technology to cardiac biomarker detection
EJ O'Reilly, PJ Conroy, S Hearty, TE Keyes, R O'Kennedy, RJ Forster, ...
RSC advances 5 (83), 67874-67877, 2015
362015
Perforin—A key (shaped) weapon in the immunological arsenal
BA Spicer, PJ Conroy, RHP Law, I Voskoboinik, JC Whisstock
Seminars in cell & developmental biology 72, 117-123, 2017
342017
Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes
H Yagi, PJ Conroy, EWW Leung, RHP Law, JA Trapani, I Voskoboinik, ...
Journal of Biological Chemistry 290 (42), 25213-25226, 2015
342015
Reconciling the structural attributes of avian antibodies
PJ Conroy, RHP Law, S Gilgunn, S Hearty, TT Caradoc-Davies, G Lloyd, ...
Journal of Biological Chemistry 289 (22), 15384-15392, 2014
342014
Cardiac troponin I: a case study in rational antibody design for human diagnostics
PJ Conroy, RJ O'Kennedy, S Hearty
Protein Engineering, Design & Selection 25 (6), 295-305, 2012
302012
Antibodies: From novel repertoires to defining and refining the structure of biologically important targets
PJ Conroy, RHP Law, TT Caradoc-Davies, JC Whisstock
Methods 116, 12-22, 2017
252017
Comprehensive N-glycan profiling of avian immunoglobulin Y
S Gilgunn, S Millán Martín, MR Wormald, J Zapatero-Rodríguez, ...
PloS one 11 (7), e0159859, 2016
242016
Circumventing the stability-function trade-off in an engineered FN3 domain
BT Porebski, PJ Conroy, N Drinkwater, P Schofield, R Vazquez-Lombardi, ...
Protein Engineering, Design and Selection 29 (11), 541-550, 2016
212016
Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
DAK Traore, JA Wisniewski, SF Flanigan, PJ Conroy, S Panjikar, YF Mok, ...
Nature communications 9 (1), 3732, 2018
202018
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