| Formation, structure, and reactivity of amino-terminated organic films on silicon substrates J Kim, P Seidler, LS Wan, C Fill Journal of colloid and interface science 329 (1), 114-119, 2009 | 350 | 2009 |
| Structure-based inhibitors of tau aggregation PM Seidler, DR Boyer, JA Rodriguez, MR Sawaya, D Cascio, K Murray, ... Nature chemistry 10 (2), 170-176, 2018 | 276 | 2018 |
| Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2 PD Patel, P Yan, PM Seidler, HJ Patel, W Sun, C Yang, NS Que, ... Nature chemical biology 9 (11), 677-684, 2013 | 207 | 2013 |
| Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED MJ De La Cruz, J Hattne, D Shi, P Seidler, J Rodriguez, FE Reyes, ... Nature methods 14 (4), 399-402, 2017 | 158 | 2017 |
| Investigations of chemical modifications of amino-terminated organic films on silicon substrates and controlled protein immobilization J Kim, J Cho, PM Seidler, NE Kurland, VK Yadavalli Langmuir 26 (4), 2599-2608, 2010 | 153 | 2010 |
| Investigations of the effect of curing conditions on the structure and stability of amino-functionalized organic films on silicon substrates by Fourier transform infrared … J Kim, P Seidler, C Fill, LS Wan Surface Science 602 (21), 3323-3330, 2008 | 98 | 2008 |
| Structure-based inhibitors of amyloid beta core suggest a common interface with tau SL Griner, P Seidler, J Bowler, KA Murray, TP Yang, S Sahay, ... Elife 8, e46924, 2019 | 91 | 2019 |
| Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation WS Shin, J Di, Q Cao, B Li, PM Seidler, KA Murray, G Bitan, L Jiang Alzheimer's research & therapy 11, 1-13, 2019 | 88 | 2019 |
| Structure-based discovery of small molecules that disaggregate Alzheimer’s disease tissue derived tau fibrils in vitro PM Seidler, KA Murray, DR Boyer, P Ge, MR Sawaya, CJ Hu, X Cheng, ... Nature communications 13 (1), 5451, 2022 | 77 | 2022 |
| Structure-based inhibitors halt prion-like seeding by Alzheimer’s disease–and tauopathy–derived brain tissue samples PM Seidler, DR Boyer, KA Murray, TP Yang, M Bentzel, MR Sawaya, ... Journal of Biological Chemistry 294 (44), 16451-16464, 2019 | 59 | 2019 |
| Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors P Krotee, SL Griner, MR Sawaya, D Cascio, JA Rodriguez, D Shi, ... Journal of Biological Chemistry 293 (8), 2888-2902, 2018 | 56 | 2018 |
| De novo designed protein inhibitors of amyloid aggregation and seeding KA Murray, CJ Hu, SL Griner, H Pan, JT Bowler, R Abskharon, ... Proceedings of the National Academy of Sciences 119 (34), e2206240119, 2022 | 31 | 2022 |
| Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease R Abskharon, PM Seidler, MR Sawaya, D Cascio, TP Yang, S Philipp, ... Journal of Biological Chemistry 295 (31), 10662-10676, 2020 | 21 | 2020 |
| Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2 E Tayeb-Fligelman, X Cheng, C Tai, JT Bowler, S Griner, MR Sawaya, ... BioRxiv, 2021.03. 05.434000, 2021 | 19 | 2021 |
| Characterization of the Grp94/OS-9 chaperone–lectin complex PM Seidler, SA Shinsky, F Hong, Z Li, MS Cosgrove, DT Gewirth Journal of molecular biology 426 (21), 3590-3605, 2014 | 19 | 2014 |
| Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils KA Murray, CJ Hu, H Pan, J Lu, R Abskharon, JT Bowler, GM Rosenberg, ... Proceedings of the National Academy of Sciences 120 (7), e2217835120, 2023 | 15 | 2023 |
| Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies KA Murray, MP Hughes, CJ Hu, MR Sawaya, L Salwinski, H Pan, ... Nature structural & molecular biology 29 (6), 529-536, 2022 | 14 | 2022 |
| CryoEM reveals how the small molecule EGCG binds to Alzheimer’s brain-derived tau fibrils and initiates fibril disaggregation PM Seidler, DR Boyer, MR Sawaya, P Ge, WS Shin, MA DeTure, ... bioRxiv, 2020.05. 29.124537, 2020 | 14 | 2020 |
| Three‐repeat and four‐repeat tau isoforms form different oligomers H Shahpasand‐Kroner, J Portillo, C Lantz, PM Seidler, N Sarafian, JA Loo, ... Protein Science 31 (3), 613-627, 2022 | 13 | 2022 |
| Structure-based inhibitors of tau aggregation. Nat Chem 10: 170–176 PM Seidler, DR Boyer, JA Rodriguez, MR Sawaya, D Cascio, K Murray, ... | 12 | 2018 |
