Thomas Westbrook
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A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
J Luo, MJ Emanuele, D Li, CJ Creighton, MR Schlabach, TF Westbrook, ...
Cell 137 (5), 835-848, 2009
A resource for large-scale RNA-interference-based screens in mammals
PJ Paddison, JM Silva, DS Conklin, M Schlabach, M Li, S Aruleba, ...
Nature 428 (6981), 427-431, 2004
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo
KL Meerbrey, G Hu, JD Kessler, K Roarty, MZ Li, JE Fang, JI Herschkowitz, ...
Proceedings of the National Academy of Sciences 108 (9), 3665-3670, 2011
Energy-stress-mediated AMPK activation inhibits ferroptosis
H Lee, F Zandkarimi, Y Zhang, JK Meena, J Kim, L Zhuang, S Tyagi, L Ma, ...
Nature cell biology 22 (2), 225-234, 2020
A genetic screen for candidate tumor suppressors identifies REST
TF Westbrook, ES Martin, MR Schlabach, Y Leng, AC Liang, B Feng, ...
Cell 121 (6), 837-848, 2005
A pan-cancer proteogenomic atlas of PI3K/AKT/mTOR pathway alterations
Y Zhang, PKS Ng, M Kucherlapati, F Chen, Y Liu, YH Tsang, ...
Cancer cell 31 (6), 820-832. e3, 2017
Integrated proteogenomic characterization of clear cell renal cell carcinoma
DJ Clark, SM Dhanasekaran, F Petralia, J Pan, X Song, Y Hu, ...
Cell 179 (4), 964-983. e31, 2019
The spliceosome is a therapeutic vulnerability in MYC-driven cancer
TYT Hsu, LM Simon, NJ Neill, R Marcotte, A Sayad, CS Bland, ...
Nature 525 (7569), 384-388, 2015
Cancer proliferation gene discovery through functional genomics
MR Schlabach, J Luo, NL Solimini, G Hu, Q Xu, MZ Li, Z Zhao, ...
Science 319 (5863), 620-624, 2008
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
JD Kessler, KT Kahle, T Sun, KL Meerbrey, MR Schlabach, EM Schmitt, ...
Science 335 (6066), 348-353, 2012
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
A Terunuma, N Putluri, P Mishra, EA Mathé, TH Dorsey, M Yi, TA Wallace, ...
The Journal of clinical investigation 124 (1), 398-412, 2014
Biology of human papillomaviruses
HR McMurray, D Nguyen, TF Westbrook, DJ McAnce
International journal of experimental pathology 82 (1), 15-33, 2001
An animal model of MYC-driven medulloblastoma
Y Pei, CE Moore, J Wang, AK Tewari, A Eroshkin, YJ Cho, H Witt, ...
Cancer cell 21 (2), 155-167, 2012
SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation
TF Westbrook, G Hu, XL Ang, P Mulligan, NN Pavlova, A Liang, Y Leng, ...
Nature 452 (7185), 370-374, 2008
The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells
H Wang, C Yu, X Gao, T Welte, AM Muscarella, L Tian, H Zhao, Z Zhao, ...
Cancer cell 27 (2), 193-210, 2015
Proteogenomic characterization of endometrial carcinoma
Y Dou, EA Kawaler, DC Zhou, MA Gritsenko, C Huang, L Blumenberg, ...
Cell 180 (4), 729-748. e26, 2020
Proteogenomic landscape of breast cancer tumorigenesis and targeted therapy
K Krug, EJ Jaehnig, S Satpathy, L Blumenberg, A Karpova, M Anurag, ...
Cell 183 (5), 1436-1456. e31, 2020
Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase
T Sun, N Aceto, KL Meerbrey, JD Kessler, C Zhou, I Migliaccio, ...
Cell 144 (5), 703-718, 2011
Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms
IS Kim, Y Gao, T Welte, H Wang, J Liu, M Janghorban, K Sheng, Y Niu, ...
Nature cell biology 21 (9), 1113-1126, 2019
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
C Huang, L Chen, SR Savage, RV Eguez, Y Dou, Y Li, ...
Cancer cell 39 (3), 361-379. e16, 2021
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