|The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease|
A Kadioglu, JN Weiser, JC Paton, PW Andrew
Nature Reviews Microbiology 6 (4), 288-301, 2008
|Alternatives to antibiotics—a pipeline portfolio review|
L Czaplewski, R Bax, M Clokie, M Dawson, H Fairhead, VA Fischetti, ...
The Lancet infectious diseases 16 (2), 239-251, 2016
|Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4|
EA McNeela, A Burke, DR Neill, C Baxter, VE Fernandes, D Ferreira, ...
PLoS pathogens 6 (11), e1001191, 2010
|Switch from planktonic to sessile life: a major event in pneumococcal pathogenesis|
MR Oggioni, C Trappetti, A Kadioglu, M Cassone, F Iannelli, S Ricci, ...
Molecular microbiology 61 (5), 1196-1210, 2006
|The role of pneumolysin in pneumococcal pneumonia and meningitis|
RA Hirst, A Kadioglu, C O'callaghan, PW Andrew
Clinical & Experimental Immunology 138 (2), 195-201, 2004
|Host cellular immune response to pneumococcal lung infection in mice|
A Kadioglu, NA Gingles, K Grattan, A Kerr, TJ Mitchell, PW Andrew
Infection and immunity 68 (2), 492-501, 2000
|Pneumococcal neuraminidases A and B both have essential roles during infection of the respiratory tract and sepsis|
S Manco, F Hernon, H Yesilkaya, JC Paton, PW Andrew, A Kadioglu
Infection and immunity 74 (7), 4014-4020, 2006
|Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux|
M Karmakar, M Katsnelson, HA Malak, NG Greene, SJ Howell, AG Hise, ...
The Journal of Immunology 194 (4), 1763-1775, 2015
|Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice|
BD Henry, DR Neill, KA Becker, S Gore, L Bricio-Moreno, R Ziobro, ...
Nature biotechnology 33 (1), 81-88, 2015
|The innate immune response to pneumococcal lung infection: the untold story|
A Kadioglu, PW Andrew
Trends in immunology 25 (3), 143-149, 2004
|Role of Manganese-Containing Superoxide Dismutase in Oxidative Stress and Virulence of Streptococcus pneumoniae|
H Yesilkaya, A Kadioglu, N Gingles, JE Alexander, TJ Mitchell, ...
Infection and immunity 68 (5), 2819-2826, 2000
|The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection|
YM Ali, NJ Lynch, KS Haleem, T Fujita, Y Endo, S Hansen, U Holmskov, ...
PLoS pathogens 8 (7), e1002793, 2012
|Sialic acid: a preventable signal for pneumococcal biofilm formation, colonization, and invasion of the host|
C Trappetti, A Kadioglu, M Carter, J Hayre, F Iannelli, G Pozzi, ...
The Journal of infectious diseases 199 (10), 1497-1505, 2009
|Upper and Lower Respiratory Tract Infection by Streptococcus pneumoniae Is Affected by Pneumolysin Deficiency and Differences in Capsule Type|
A Kadioglu, S Taylor, F Iannelli, G Pozzi, TJ Mitchell, PW Andrew
Infection and immunity 70 (6), 2886-2890, 2002
|Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults|
DM Ferreira, DR Neill, M Bangert, JF Gritzfeld, N Green, AKA Wright, ...
American journal of respiratory and critical care medicine 187 (8), 855-864, 2013
|CD4-T-lymphocyte interactions with pneumolysin and pneumococci suggest a crucial protective role in the host response to pneumococcal infection|
A Kadioglu, W Coward, MJ Colston, CRA Hewitt, PW Andrew
Infection and immunity 72 (5), 2689-2697, 2004
|Phage therapy is highly effective against chronic lung infections with Pseudomonas aeruginosa|
EM Waters, DR Neill, B Kaman, JS Sahota, MRJ Clokie, C Winstanley, ...
Thorax 72 (7), 666-667, 2017
|Protein Serine/Threonine Kinase StkP Positively Controls Virulence and Competence in Streptococcus pneumoniae|
J Echenique, A Kadioglu, S Romao, PW Andrew, MC Trombe
Infection and immunity 72 (4), 2434-2437, 2004
|Role of genetic resistance in invasive pneumococcal infection: identification and study of susceptibility and resistance in inbred mouse strains|
NA Gingles, JE Alexander, A Kadioglu, PW Andrew, A Kerr, TJ Mitchell, ...
Infection and immunity 69 (1), 426-434, 2001
|Capsule Type of Streptococcus pneumoniae Determines Growth Phenotype|
LJ Hathaway, SD Brugger, B Morand, M Bangert, JU Rotzetter, C Hauser, ...
PLoS pathogens 8 (3), e1002574, 2012