| New developments in RiPP discovery, enzymology and engineering M Montalbán-López, TA Scott, S Ramesh, IR Rahman, AJ Van Heel, ... Natural product reports 38 (1), 130-239, 2021 | 475 | 2021 |
| Demonstration That the Radical S-Adenosylmethionine (SAM) Enzyme PqqE Catalyzes de Novo Carbon-Carbon Cross-linking within a Peptide Substrate PqqA in the Presence of the … I Barr, JA Latham, AT Iavarone, T Chantarojsiri, JD Hwang, JP Klinman Journal of Biological Chemistry 291 (17), 8877-8884, 2016 | 114 | 2016 |
| PqqD is a novel peptide chaperone that forms a ternary complex with the radical S-adenosylmethionine protein PqqE in the pyrroloquinoline quinone biosynthetic pathway JA Latham, AT Iavarone, I Barr, PV Juthani, JP Klinman Journal of Biological Chemistry 290 (20), 12908-12918, 2015 | 88 | 2015 |
| Mechanistic elucidation of the mycofactocin-biosynthetic radical S-adenosylmethionine protein, MftC B Khaliullin, R Ayikpoe, M Tuttle, JA Latham Journal of Biological Chemistry 292 (31), 13022-13033, 2017 | 61 | 2017 |
| Mycofactocin biosynthesis: modification of the peptide MftA by the radical S‐adenosylmethionine protein MftC B Khaliullin, P Aggarwal, M Bubas, GR Eaton, SS Eaton, JA Latham FEBS letters 590 (16), 2538-2548, 2016 | 54 | 2016 |
| Effects of alkoxy groups on arene rings of lignin β-O-4 model compounds on the efficiencies of single electron transfer-promoted photochemical and enzymatic C–C bond cleavage … SH Lim, K Nahm, CS Ra, DW Cho, UC Yoon, JA Latham, ... The Journal of organic chemistry 78 (18), 9431-9443, 2013 | 48 | 2013 |
| Nuclear magnetic resonance structure and binding studies of PqqD, a chaperone required in the biosynthesis of the bacterial dehydrogenase cofactor pyrroloquinoline quinone RL Evans III, JA Latham, Y Xia, JP Klinman, CM Wilmot Biochemistry 56 (21), 2735-2746, 2017 | 44 | 2017 |
| Regioselectivity of enzymatic and photochemical single electron transfer promoted carbon− carbon bond fragmentation reactions of tetrameric lignin model compounds DW Cho, JA Latham, HJ Park, UC Yoon, P Langan, D Dunaway-Mariano, ... The Journal of Organic Chemistry 76 (8), 2840-2852, 2011 | 42 | 2011 |
| X-ray and EPR characterization of the auxiliary Fe–S clusters in the radical SAM enzyme PqqE I Barr, TA Stich, AS Gizzi, TL Grove, JB Bonanno, JA Latham, T Chung, ... Biochemistry 57 (8), 1306-1315, 2018 | 37 | 2018 |
| Discovery of hydroxylase activity for PqqB provides a missing link in the pyrroloquinoline quinone biosynthetic pathway EM Koehn, JA Latham, T Armand, RL Evans III, X Tu, CM Wilmot, ... Journal of the American Chemical Society 141 (10), 4398-4405, 2019 | 33 | 2019 |
| Spectroscopic and electrochemical characterization of the mycofactocin biosynthetic protein, MftC, provides insight into its redox flipping mechanism R Ayikpoe, T Ngendahimana, M Langton, S Bonitatibus, LM Walker, ... Biochemistry 58 (7), 940-950, 2019 | 32 | 2019 |
| Occurrence, function, and biosynthesis of mycofactocin R Ayikpoe, V Govindarajan, JA Latham Applied microbiology and biotechnology 103, 2903-2912, 2019 | 29 | 2019 |
| Divergence of Substrate Specificity and Function in the Escherichia coli Hotdog-fold Thioesterase Paralogs YdiI and YbdB JA Latham, D Chen, KN Allen, D Dunaway-Mariano Biochemistry 53 (29), 4775-4787, 2014 | 28 | 2014 |
| The Catalytic Mechanism of the Hotdog-fold Enzyme Superfamily 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. Strain SU F Song, JB Thoden, Z Zhuang, J Latham, M Trujillo, HM Holden, ... Biochemistry 51 (35), 7000-7016, 2012 | 28 | 2012 |
| MftD catalyzes the formation of a biologically active redox center in the biosynthesis of the ribosomally synthesized and post-translationally modified redox cofactor mycofactocin RS Ayikpoe, JA Latham Journal of the American Chemical Society 141 (34), 13582-13591, 2019 | 26 | 2019 |
| A two-component protease in Methylorubrum extorquens with high activity toward the peptide precursor of the redox cofactor pyrroloquinoline quinone AM Martins, JA Latham, PJ Martel, I Barr, AT Iavarone, JP Klinman Journal of Biological Chemistry 294 (41), 15025-15036, 2019 | 25 | 2019 |
| At the confluence of ribosomally synthesized peptide modification and radical S-adenosylmethionine (SAM) enzymology JA Latham, I Barr, JP Klinman Journal of Biological Chemistry 292 (40), 16397-16405, 2017 | 24 | 2017 |
| Human brown fat inducible thioesterase variant 2 cellular localization and catalytic function D Chen, J Latham, H Zhao, M Bisoffi, J Farelli, D Dunaway-Mariano Biochemistry 51 (35), 6990-6999, 2012 | 22 | 2012 |
| Mycofactocin Biosynthesis Proceeds through 3-Amino-5-[(p-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone (AHDP); Direct Observation of MftE Specificity … R Ayikpoe, J Salazar, B Majestic, JA Latham Biochemistry 57 (37), 5379-5383, 2018 | 21 | 2018 |
| Photochemical and enzymatic SET promoted C–C bond cleavage reactions of lignin β-1 model compounds containing varying number of methoxy substituents on their arene rings SH Lim, WS Lee, YI Kim, Y Sohn, DW Cho, C Kim, E Kim, JA Latham, ... Tetrahedron 71 (24), 4236-4247, 2015 | 17 | 2015 |
