Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells A Rezania, JE Bruin, P Arora, A Rubin, I Batushansky, A Asadi, S O'dwyer, ... Nature biotechnology 32 (11), 1121-1133, 2014 | 1692 | 2014 |
Maturation of human embryonic stem cell–derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice A Rezania, JE Bruin, MJ Riedel, M Mojibian, A Asadi, J Xu, R Gauvin, ... Diabetes 61 (8), 2016-2029, 2012 | 720 | 2012 |
Hyperinsulinemia drives diet-induced obesity independently of brain insulin production AE Mehran, NM Templeman, GS Brigidi, GE Lim, KY Chu, X Hu, ... Cell metabolism 16 (6), 723-737, 2012 | 622 | 2012 |
The pancreatic β cell is a key site for mediating the effects of leptin on glucose homeostasis SD Covey, RD Wideman, C McDonald, S Unniappan, F Huynh, A Asadi, ... Cell metabolism 4 (4), 291-302, 2006 | 255 | 2006 |
Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo Y Fujita, RD Wideman, M Speck, A Asadi, DS King, TD Webber, ... American Journal of Physiology-Endocrinology and Metabolism 296 (3), E473-E479, 2009 | 242 | 2009 |
Immunohistochemical characterisation of cells co-producing insulin and glucagon in the developing human pancreas MJ Riedel, A Asadi, R Wang, Z Ao, GL Warnock, TJ Kieffer Diabetologia 55, 372-381, 2012 | 202 | 2012 |
Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet α-cells and promotes insulin secretion Y Fujita, RD Wideman, A Asadi, GK Yang, R Baker, T Webber, T Zhang, ... Gastroenterology 138 (5), 1966-1975. e1, 2010 | 176 | 2010 |
Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells JE Bruin, S Erener, J Vela, X Hu, JD Johnson, HT Kurata, FC Lynn, ... Stem cell research 12 (1), 194-208, 2014 | 174 | 2014 |
Duodenal-jejunal bypass protects GK rats from β-cell loss and aggravation of hyperglycemia and increases enteroendocrine cells coexpressing GIP and GLP-1 M Speck, YM Cho, A Asadi, F Rubino, TJ Kieffer American Journal of Physiology-Endocrinology and Metabolism 300 (5), E923-E932, 2011 | 134 | 2011 |
A GIP receptor agonist exhibits β-cell anti-apoptotic actions in rat models of diabetes resulting in improved β-cell function and glycemic control SB Widenmaier, SJ Kim, GK Yang, T De Los Reyes, C Nian, A Asadi, ... PloS one 5 (3), e9590, 2010 | 125 | 2010 |
Treating diet-induced diabetes and obesity with human embryonic stem cell-derived pancreatic progenitor cells and antidiabetic drugs JE Bruin, N Saber, N Braun, JK Fox, M Mojibian, A Asadi, C Drohan, ... Stem cell reports 4 (4), 605-620, 2015 | 101 | 2015 |
Accelerated maturation of human stem cell-derived pancreatic progenitor cells into insulin-secreting cells in immunodeficient rats relative to mice JE Bruin, A Asadi, JK Fox, S Erener, A Rezania, TJ Kieffer Stem cell reports 5 (6), 1081-1096, 2015 | 88 | 2015 |
Differential processing of pro-glucose-dependent insulinotropic polypeptide in gut Y Fujita, A Asadi, GK Yang, YN Kwok, TJ Kieffer American Journal of Physiology-Gastrointestinal and Liver Physiology 298 (5 …, 2010 | 71 | 2010 |
Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes M Szabat, TB Kalynyak, GE Lim, KY Chu, YH Yang, A Asadi, BK Gage, ... Cell death & disease 2 (11), e232-e232, 2011 | 63 | 2011 |
Revisiting proinsulin processing: evidence that human β-cells process proinsulin with prohormone convertase (PC) 1/3 but not PC2 A Ramzy, A Asadi, TJ Kieffer Diabetes 69 (7), 1451-1462, 2020 | 56 | 2020 |
Implanted islets in the anterior chamber of the eye are prone to autoimmune attack in a mouse model of diabetes M Mojibian, B Harder, A Hurlburt, JE Bruin, A Asadi, TJ Kieffer Diabetologia 56, 2213-2221, 2013 | 51 | 2013 |
The role of ARX in human pancreatic endocrine specification BK Gage, A Asadi, RK Baker, TD Webber, R Wang, M Itoh, M Hayashi, ... PLoS One 10 (12), e0144100, 2015 | 50 | 2015 |
Ontogeny of ghrelin, obestatin, preproghrelin, and prohormone convertases in rat pancreas and stomach P Walia, A Asadi, TJ Kieffer, JD Johnson, JP Chanoine Pediatric Research 65 (1), 39-44, 2009 | 49 | 2009 |
Dual role of interleukin‐1β in islet amyloid formation and its β‐cell toxicity: I mplications for type 2 diabetes and islet transplantation YJ Park, GL Warnock, Z Ao, N Safikhan, M Meloche, A Asadi, TJ Kieffer, ... Diabetes, Obesity and Metabolism 19 (5), 682-694, 2017 | 47 | 2017 |
DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes MJ Riedel, DF Gaddy, A Asadi, PD Robbins, TJ Kieffer Gene Therapy 17 (2), 171-180, 2010 | 40 | 2010 |