| CMTM3, located at the critical tumor suppressor locus 16q22. 1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis Y Wang, J Li, Y Cui, T Li, KM Ng, H Geng, H Li, X Shu, H Li, W Liu, B Luo, ... Cancer research 69 (12), 5194-5201, 2009 | 131 | 2009 |
| Protocadherin 17 acts as a tumour suppressor inducing tumour cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers X Hu, X Sui, L Li, X Huang, R Rong, X Su, Q Shi, L Mo, X Shu, Y Kuang, ... The Journal of pathology 229 (1), 62-73, 2013 | 125 | 2013 |
| The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas L Li, J Ying, H Li, Y Zhang, X Shu, Y Fan, J Tan, Y Cao, SW Tsao, ... Oncogene 31 (34), 3901-3912, 2012 | 114 | 2012 |
| DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer X Yin, T Xiang, LL Li, X Su, X Shu, X Luo, J Huang, Y Yuan, W Peng, ... Breast cancer research 15, 1-12, 2013 | 103 | 2013 |
| The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors X Shu, H Geng, L Li, J Ying, C Ma, Y Wang, FF Poon, X Wang, Y Ying, ... PloS one 6 (11), e27346, 2011 | 97 | 2011 |
| Phospholipase C delta 1 is a novel 3p22. 3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer XT Hu, FB Zhang, YC Fan, XS Shu, AHY Wong, W Zhou, QL Shi, HM Tang, ... Oncogene 28 (26), 2466-2475, 2009 | 81 | 2009 |
| GSK3β-mediated tau hyperphosphorylation triggers diabetic retinal neurodegeneration by disrupting synaptic and mitochondrial functions H Zhu, W Zhang, Y Zhao, X Shu, W Wang, D Wang, Y Yang, Z He, ... Molecular Neurodegeneration 13, 1-17, 2018 | 70 | 2018 |
| Epigenetic disruption of cell signaling in nasopharyngeal carcinoma LL Li, XS Shu, ZH Wang, Y Cao, Q Tao Chinese journal of cancer 30 (4), 231, 2011 | 67 | 2011 |
| A global survey of bacterial type III secretion systems and their effectors Y Hu, H Huang, X Cheng, X Shu, AP White, J Stavrinides, W Köster, ... Environmental Microbiology 19 (10), 3879-3895, 2017 | 65 | 2017 |
| A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors JSW Low, Q Tao, KM Ng, HK Goh, XS Shu, WL Woo, RF Ambinder, ... Oncogene 30 (16), 1923-1935, 2011 | 62 | 2011 |
| FEZF2 , a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated … X Shu, L Li, M Ji, Y Cheng, J Ying, Y Fan, L Zhong, X Liu, SW Tsao, ... Carcinogenesis 34 (9), 1984-1993, 2013 | 59 | 2013 |
| Epigenetic identification of receptor tyrosine kinase-like orphan receptor 2 as a functional tumor suppressor inhibiting β-catenin and AKT signaling but frequently methylated … L Li, J Ying, X Tong, L Zhong, X Su, T Xiang, X Shu, R Rong, L Xiong, H Li, ... Cellular and molecular life sciences 71, 2179-2192, 2014 | 55 | 2014 |
| Overexpression of a novel candidate oncogene KIF14 correlates with tumor progression and poor prognosis in prostate cancer Y Zhang, Y Yuan, P Liang, Z Zhang, X Guo, L Xia, Y Zhao, XS Shu, S Sun, ... Oncotarget 8 (28), 45459, 2017 | 52 | 2017 |
| Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1 Y Ying, Y Wang, X Huang, Y Sun, J Zhang, M Li, J Zeng, M Wang, W Xiao, ... Oncogene 39 (5), 1004-1017, 2020 | 48 | 2020 |
| The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid‐inducible gene‐I‐like receptor signalling and is a potential … X Shu, Y Zhao, Y Sun, L Zhong, Y Cheng, Y Zhang, K Ning, Q Tao, ... The Journal of pathology 244 (1), 36-48, 2018 | 37 | 2018 |
| Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy KD Rolev, X Shu, Y Ying Neuropharmacology 187, 108498, 2021 | 35 | 2021 |
| Neuroprotective effects of ginsenoside Rg1 against hyperphosphorylated tau-induced diabetic retinal neurodegeneration via activation of IRS-1/Akt/GSK3β signaling Y Ying, Y Zhang, C Ma, M Li, C Tang, Y Yang, J Zeng, X Huang, J Yi, ... Journal of Agricultural and Food Chemistry 67 (30), 8348-8360, 2019 | 33 | 2019 |
| CDCA2 inhibits apoptosis and promotes cell proliferation in prostate cancer and is directly regulated by HIF-1α pathway Y Zhang, Y Cheng, Z Zhang, Z Bai, H Jin, X Guo, X Huang, M Li, M Wang, ... Frontiers in oncology 10, 725, 2020 | 32 | 2020 |
| Topical ocular administration of the GLP-1 receptor agonist liraglutide arrests hyperphosphorylated tau-triggered diabetic retinal neurodegeneration via activation of GLP-1R … X Shu, Y Zhang, M Li, X Huang, Y Yang, J Zeng, Y Zhao, X Wang, ... Neuropharmacology 153, 1-12, 2019 | 31 | 2019 |
| OSR1 is a novel epigenetic silenced tumor suppressor regulating invasion and proliferation in renal cell carcinoma Y Zhang, Y Yuan, P Liang, X Guo, Y Ying, XS Shu, M Gao, Y Cheng Oncotarget 8 (18), 30008, 2017 | 29 | 2017 |
