Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Cancer discovery 5 (12), 1282-1295, 2015 | 1201 | 2015 |
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity E Jacoby, SM Nguyen, TJ Fountaine, K Welp, B Gryder, H Qin, Y Yang, ... Nature communications 7 (1), 12320, 2016 | 409 | 2016 |
Early and late hematologic toxicity following CD19 CAR-T cells S Fried, A Avigdor, B Bielorai, A Meir, MJ Besser, J Schachter, A Shimoni, ... Bone marrow transplantation 54 (10), 1643-1650, 2019 | 330 | 2019 |
MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1 A Bier, N Giladi, N Kronfeld, HK Lee, S Cazacu, S Finniss, C Xiang, ... Oncotarget 4 (5), 665, 2013 | 215 | 2013 |
Clinical utilization of chimeric antigen receptor T cells in B cell acute lymphoblastic leukemia: an expert opinion from the European Society for Blood and Marrow … AJ Kansagra, NV Frey, M Bar, TW Laetsch, PA Carpenter, BN Savani, ... Biology of blood and marrow transplantation 25 (3), e76-e85, 2019 | 202* | 2019 |
TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance Y Yang, ME Kohler, CD Chien, CT Sauter, E Jacoby, C Yan, Y Hu, ... Science translational medicine 9 (417), eaag1209, 2017 | 186 | 2017 |
MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth Y Nemlich, E Greenberg, R Ortenberg, MJ Besser, I Barshack, ... The Journal of clinical investigation 123 (6), 2703-2718, 2013 | 176 | 2013 |
Gamma-delta CAR-T cells show CAR-directed and independent activity against leukemia M Rozenbaum, A Meir, Y Aharony, O Itzhaki, J Schachter, I Bank, ... Frontiers in immunology 11, 1347, 2020 | 168 | 2020 |
Use of chimeric antigen receptor T cell therapy in clinical practice for relapsed/refractory aggressive B cell non-Hodgkin lymphoma: an expert panel opinion from the American … T Jain, M Bar, AJ Kansagra, EA Chong, SK Hashmi, SS Neelapu, M Byrne, ... Biology of Blood and Marrow Transplantation 25 (12), 2305-2321, 2019 | 164 | 2019 |
MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor HK Lee, A Bier, S Cazacu, S Finniss, C Xiang, H Twito, LM Poisson, ... PloS one 8 (2), e54652, 2013 | 129 | 2013 |
Murine allogeneic CD19 CAR T cells harbor potent antileukemic activity but have the potential to mediate lethal GVHD E Jacoby, Y Yang, H Qin, CD Chien, JN Kochenderfer, TJ Fry Blood, The Journal of the American Society of Hematology 127 (10), 1361-1370, 2016 | 114 | 2016 |
Challenges and opportunities of allogeneic donor-derived CAR T cells Y Yang, E Jacoby, TJ Fry Current opinion in hematology 22 (6), 509-515, 2015 | 114 | 2015 |
Locally produced CD19 CAR T cells leading to clinical remissions in medullary and extramedullary relapsed acute lymphoblastic leukemia E Jacoby, B Bielorai, A Avigdor, O Itzhaki, D Hutt, V Nussboim, A Meir, ... American journal of hematology 93 (12), 1485-1492, 2018 | 103 | 2018 |
Updates on CAR T‐cell therapy in B‐cell malignancies E Jacoby, SA Shahani, NN Shah Immunological reviews 290 (1), 39-59, 2019 | 74 | 2019 |
Murine models of acute leukemia: important tools in current pediatric leukemia research E Jacoby, CD Chien, TJ Fry Frontiers in oncology 4, 95, 2014 | 62 | 2014 |
Single-agent post-transplantation cyclophosphamide as graft-versus-host disease prophylaxis after human leukocyte antigen–matched related bone marrow transplantation for … E Jacoby, A Chen, DM Loeb, CJ Gamper, E Zambidis, NJ Llosa, J Huo, ... Biology of Blood and Marrow Transplantation 22 (1), 112-118, 2016 | 50 | 2016 |
Head-to-head comparison of in-house produced CD19 CAR-T cell in ALL and NHL patients O Itzhaki, E Jacoby, A Nissani, M Levi, A Nagler, A Kubi, K Brezinger, ... Journal for immunotherapy of cancer 8 (1), 2020 | 49 | 2020 |
The role of allogeneic HSCT after CAR T cells for acute lymphoblastic leukemia E Jacoby Bone Marrow Transplantation 54 (Suppl 2), 810-814, 2019 | 40 | 2019 |
Epigenetic profiling and response to CD19 chimeric antigen receptor T-cell therapy in B-cell malignancies CA Garcia-Prieto, L Villanueva, A Bueno-Costa, V Davalos, ... JNCI: Journal of the National Cancer Institute 114 (3), 436-445, 2022 | 34 | 2022 |
CD19 CAR T-cells for pediatric relapsed acute lymphoblastic leukemia with active CNS involvement: a retrospective international study E Jacoby, S Ghorashian, B Vormoor, B De Moerloose, N Bodmer, ... Leukemia 36 (6), 1525-1532, 2022 | 33 | 2022 |