Siah-1 mediates a novel β-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein J Liu, J Stevens, CA Rote, HJ Yost, Y Hu, KL Neufeld, RL White, ... Molecular cell 7 (5), 927-936, 2001 | 537 | 2001 |
Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development R Smits, MF Kielman, C Breukel, C Zurcher, K Neufeld, ... Genes & development 13 (10), 1309-1321, 1999 | 298 | 1999 |
APC-mediated downregulation of β-catenin activity involves nuclear sequestration and nuclear export KL Neufeld, F Zhang, BR Cullen, RL White EMBO reports 1 (6), 519-523, 2000 | 241 | 2000 |
Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm KL Neufeld, DA Nix, H Bogerd, Y Kang, MC Beckerle, BR Cullen, ... Proceedings of the National Academy of Sciences 97 (22), 12085-12090, 2000 | 199 | 2000 |
Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling GH Ashton, JP Morton, K Myant, TJ Phesse, RA Ridgway, V Marsh, ... Developmental cell 19 (2), 259-269, 2010 | 197 | 2010 |
Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein KL Neufeld, RL White Proceedings of the National Academy of Sciences 94 (7), 3034-3039, 1997 | 153 | 1997 |
Phosphorylation near nuclear localization signal regulates nuclear import of adenomatous polyposis coli protein F Zhang, RL White, KL Neufeld Proceedings of the National Academy of Sciences 97 (23), 12577-12582, 2000 | 149 | 2000 |
Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon CB Anderson, KL Neufeld, RL White Proceedings of the National Academy of Sciences 99 (13), 8683-8688, 2002 | 135 | 2002 |
Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1 L Lan, C Appelman, AR Smith, J Yu, S Larsen, RT Marquez, H Liu, X Wu, ... Molecular oncology 9 (7), 1406-1420, 2015 | 130 | 2015 |
Purification, characterization, and comparison of poliovirus RNA polymerase from native and recombinant sources. KL Neufeld, OC Richards, E Ehrenfeld Journal of Biological Chemistry 266 (35), 24212-24219, 1991 | 91 | 1991 |
Cell density and phosphorylation control the subcellular localization of adenomatous polyposis coli protein F Zhang, RL White, KL Neufeld Molecular and cellular biology 21 (23), 8143-8156, 2001 | 89 | 2001 |
Identification of terminal adenylyl transferase activity of the poliovirus polymerase 3Dpol KL Neufeld, JM Galarza, OC Richards, DF Summers, E Ehrenfeld Journal of virology 68 (9), 5811-5818, 1994 | 88 | 1994 |
Tumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression AR Smith, RT Marquez, WC Tsao, S Pathak, A Roy, J Ping, B Wilkerson, ... Oncotarget 6 (14), 12558, 2015 | 79 | 2015 |
APC controls Wnt-induced β-catenin destruction complex recruitment in human colonocytes TW Parker, KL Neufeld Scientific reports 10 (1), 2957, 2020 | 76 | 2020 |
Nuclear APC KL Neufeld APC Proteins, 13-29, 2009 | 60 | 2009 |
More than two decades of Apc modeling in rodents M Zeineldin, KL Neufeld Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1836 (1), 80-89, 2013 | 59 | 2013 |
Novel double-negative feedback loop between adenomatous polyposis coli and Musashi1 in colon epithelia E Spears, KL Neufeld Journal of Biological Chemistry 286 (7), 4946-4950, 2011 | 53 | 2011 |
Interaction between tumor suppressor adenomatous polyposis coli and topoisomerase IIα: implication for the G2/M transition Y Wang, Y Azuma, D Moore, N Osheroff, KL Neufeld Molecular biology of the cell 19 (10), 4076-4085, 2008 | 46 | 2008 |
Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins L Lan, H Liu, AR Smith, C Appelman, J Yu, S Larsen, RT Marquez, X Wu, ... BMC cancer 18, 1-14, 2018 | 42 | 2018 |
Understanding phenotypic variation in rodent models with germline Apc mutations M Zeineldin, KL Neufeld Cancer research 73 (8), 2389-2399, 2013 | 42 | 2013 |